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Background Calcium imaging is based on the detection of minute signal changes in an image time-series encompassing pre- and post-stimuli. Depending on the function of the elicited response, change may be pronounced, as in the case of a genetically encoded calcium-reporter protein, or subtle, as is the case in a bath-applied dye system. Large datasets are thus often acquired and appraised only duri

This paper describes a heterogeneous competitive flow immunoassay with a high sample throughput which can be used for the screening of smaller analytes in various samples. The method is based on off-line incubation of the analyte (Ag), a fluorescent labelled tracer (Ag*) and the corresponding antibody (Ab). The separation of bound (Ab-Ag*) and free tracer (Ag*) is based on a size exclusion and rev

This paper proposes an IV-based panel unit root test that is general enough to accommodate general error serial and cross-section dependence, and a potentially nonlinear deterministic trend function. These allowances make the new test one of the most general around. It is also very simple to implement. Indeed, the IV statistic is asymptotically invariant to not only to all nuisance parameters char

The regulatory credit value adjustment (CVA) for an outstanding over-the-counter (OTC) derivative portfolio is computed based on the portfolio exposure over its lifetime. Usually, the future portfolio exposure is approximated using the Monte Carlo simulation, as the portfolio value can be driven by several market risk-factors. For derivatives, such as Bermudan swaptions, that do not have an analyt

This paper presents a computationally efficient technique for the computation of exposure distributions at any future time under the risk-neutral and some observed real-world probability measures; these are needed for the computation of credit valuation adjustment (CVA) and potential future exposure (PFE). In particular,we present a valuation framework for Bermudan swaptions. The essential idea is

The review presented in this paper aims to describe the state-of-the art concerning methods for measuring societal resilience. A literature search is conducted where 36 recently published methods are selected. Then, various questions are explored concerning the methods, such as how resilience is operationalized, how data is collected, and about their normative foundation. Several methods exist wit

Theoretical and empirical studies prove the strong relationship between social factors and the individual linguistic attitudes. Different social categories, such as gender, age, education, profession and social status, are strongly related with the linguistic diversity of people’s everyday spoken and written interaction. In this paper, sociolinguistic studies addressed to gender differentiation ar

Developing an ability to independently formulate research questions is an important goal in doctoral education. During a seminar in the “Docent course”, accredited by Genombrottet at Lund University, the authors behind this paper ended up in a discussion on the actual conditions for developing such ability. During the discussions, the authors, based on their own experiences, identified several con

In this study steady-state natural convection for Al2O3 and CuO nanofluids inside different enclosures are numerically investigated. Natural convection is concerned due to a temperature difference between hot and cold surfaces. Rectangular and curved enclosures are investigated. The Boussinesq approximation is used to form the governing equations and the commercial software package ANSYS Fluent ve

Migratory songbirds carry an inherited capacity to migrate several thousand kilometers each year crossing continental landmasses and barriers between distant breeding sites and wintering areas. How individual songbirds manage with extreme precision to find their way is still largely unknown. The functional characteristics of biological compasses used by songbird migrants has mainly been investigat

Background While effective vocational methods for gaining employment exist for people with schizophrenia and similar conditions, no evidence exists with regard to people with affective disorders. We aimed to study the effectiveness of a newly developed Individual Enabling and Support (IES) model adapted for the target group and compared to traditional vocational rehabilitation (TVR). Methods An as

Ion beam analysis has for decades been used as a tool for geochemical analysis of trace elements using both X-rays (particle induced X-ray emission) and nuclear reaction analysis. With the geoanalytical setup at the Lund Ion Beam Analysis Facility, the boron content in geological samples with a spatial resolution of 1 µm is determined through nuclear reaction analysis. In the newly upgraded setup,

Fires in enclosures equipped with mechanical ventilation remain one of the key issues for fire safety assessment in multifamily homes and industries. Therefore, a wide variation of methods for preventing smoke spread through the ventilation system exist and are applied, in performance-based designs. Through the use of the heating, ventilation and air conditioning (HVAC) model in the fire dynamics

Background: High amounts of alkali in the fuel, such as potassium and sodium in combination with high amounts of chlorine increase the chances of high-temperature corrosion, deposit growth and slagging and fouling. These risks need to be reduced to avoid losses in revenue due to unplanned stops and costs related to increased maintenance. Aims:This research targets the development of a new cell to

Empiriska inventeringar över kollektivtrafikens roll i den regionala- och kommunala praktiken är ovanliga eller så vitt vi känner till obefintliga. Med denna rapport vill vi ge en överblick och beskrivning av vilken roll och vilka värden som beslutsfattare i regioner och kommuner tillmäter kollektivtrafiken i Sverige och vad denna förväntas att bidra med på den lokala samhällsnivån. Ambitionen är