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Nonsense-mediated mRNA decay (NMD) is a post-transcriptional surveillance process that eliminates mRNAs containing premature termination codons (PTCs). NMD has been hypothesized to impact on several aspects of cellular function; however, its importance in the context of a mammalian organism has not been addressed in detail. Here we use mouse genetics to demonstrate that hematopoietic-specific dele
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Economic Growth is often cited as a driving force behind electricity consumption. Pakistan has an under-developed Electricity Sector, and this restrains the economic activities in the country. Load-shedding, which are power outages scheduled by the government, are a frequent occurrence, and these outages affect all sectors of the Pakistani economy. The Energy Crisis (based on electricity shortage)