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Background. Several studies have investigated associations between the -174GC single nucleotide polymorphism (rs1800795) of the IL6 gene and phenotypes related to type 2 diabetes mellitus (T2DM) but presented inconsistent results. Aims. This joint analysis aimed to clarify whether IL6 -174GC was associated with glucose and circulating interleukin-6 concentrations as well as body mass index (BMI).

One of the most important trends in contemporary tourism is the increase in urban tourism, both in absolute and in relative terms. An increasing number of cities have become significant tourism destinations. Cities also attract an increasingly diverse set of visitors, some of which could be called alternative tourists. The development of alternative tourism is related to decreasing relative costs One of the most important trends in contemporary tourism is the increase in urban tourism, both in absolute and in relative terms. An increasing number of cities have become significant tourism destinations. Cities also attract an increasingly diverse set of visitors, some of which could be called alternative tourists. The development of alternative tourism is related to decreasing relative costs

In a controlled and randomised double-blind study, 26 healthy adult volunteers consumed, for 21 d, 400 ml of a rose-hip drink containing oats (0.7 g/100ml) fermented with Lactobacillus plantarum DSM 9843 (RHL; containing 5 x 10(7) cfu ml(-1)), and 22 volunteers in a second group the same amount of a pure rose-hip drink (RH). Significant increases in the total faecal concentration of carboxylic aci

AbstractThe purpose of this study was to document historical trends and socioeconomic inequalities in ill health outcomes related to alcohol consumption, narcotics use and tobacco smoking over the seventeen years prior to the implementation of the Swedish government’s first strategy for alcohol, narcotics, doping and tobacco (ANDT) in 2011. We also sought to explain the changes over time in terms The purpose of this study was to document historical trends and socioeconomic inequalities in ill health outcomes related to alcohol consumption, narcotics use and tobacco smoking over the seventeen years prior to the implementation of the Swedish government’s first strategy for alcohol, narcotics, doping and tobacco (ANDT) in 2011. We also sought to explain the changes over time in terms of chang

Brewer's spent grain (BSG) accounts for around 85% of the solid by-products from beer production. BSG was first extracted to obtain water-soluble arabinoxylan (AX). Using subsequent alkali extraction (0.5 M KOH) it was possible to dissolve additional AX. In total, about 57% of the AX in BSG was extracted with the purity of 45–55%. After comparison of nine xylanases, Pentopan mono BG, a GH11 enzyme

Background: It has been demonstrated that weight loss improves symptoms in obese subjects with knee osteoarthritis (KOA). A parallel change in cartilage morphology remains to be demonstrated. Purpose: To demonstrate a parallel change in cartilage morphology. Material and Methods: Obese patients with KOA were examined before and after weight loss over 16 weeks. Target knee joints were radiographica

Summary Alternative treatments for seborrhoeic dermatitis are needed because of the increasing risk of anti-fungal resistance to existing therapies. To investigate the efficacy, safety and tolerability of topical scalp treatment with K301 solution. Two multi-centre, randomised, double-blind studies were conducted. Study I: 4 weeks of once-daily treatment with either one form of K301 (a or b) or pl

OBJECTIVE: To identify factors predicting response to first TNF blocking treatment course in patients with established RA with a special focus on gender differences. METHODS: Patients with active RA initiating their first treatment course of TNF-blocking therapy were enrolled. The study period was March 1999 through September 2006. The prospective protocol included information on demographics, cli

Mexico City’s water system is not sustainable. There is an unfair inequality gap in the quantity and quality of water access for its residents. Moreover, the groundwater aquifers in the city are being over-exploited and polluted. This has resulted in the sinking of the city, damage to the ecosystems, and the reduction of water access to Mexico City’s residents. As the policies are a direct instrum

Popular science Biogenic volatile organic compounds (BVOCs) are a versatile group of non-methane hydrocarbons (chemical compounds made of carbon and hydrogen) emitted by vegetation. The most common BVOCs from plants are some chemical compounds like isoprene, monoterpenes and sesquiterpenes. BVOCs are involved in plant growth, reproduction and defense mechanisms. Besides, BVOC play an important rol

This essay provides an analysis of the relation between the value added tax (VAT) and the size of the informal sector in Africa. The proposed hypothesis is that due to incentive mechanisms provided by VAT, tax evasion, and hence the size of the informal sector, should decrease when VAT replaces other standard consumption taxes, primarily the retail sales tax (RST) and the turnover tax (TOT). The

Popular Abstract in English Antonie van Leeuwenhoek is known as the father of microbiology, because he made the first microscopic observation of bacteria in human history, published in 1683. For the naked human eyes, bacterial cells are too small to observe, and the development of microscopy techniques has since then been fundamental for examining bacterial cells. Recent advances in visualizing toCoiled coil proteins emerge as important determinants of bacterial cellular organization. Several such proteins display properties characteristic to metazoan intermediate filament (IF) proteins, and are therefore designated bacterial IF-like proteins. The best studied examples of the latter are crescentin in Caulobacter crescentus that determines the curved cell shape, and FilP (filament forming-p

Popular Abstract in Swedish Avhandlingen utgörs av studier av smärtupplevelse i olika befolkningsgrupper. I fokus för analyserna står smärtans totala utbredning. Ett beteendepsykolo-giskt perspektiv har applicerats på psykosociala aspekter av betydelse för att hantera den kroniska smärtan. Alla studier har genomförts på urval av Malmöbefolkningen. Bakgrund. Smärtrelaterad arbetsoförmåga är ett foMusculoskeletal pain-related vocational dysfunction is a major public health problem. The solution is beyond the scope of biomedicine, but the problem could well be analyzed in the complementary, cognitive-behavior psychological frame of reference. In order to better prevent the development of pain-related dysfunction: The sociodemographic milieu of dysfunctional chronic pain patients was examined

Patients with chronic heart failure (CHF) show impaired health-related quality of life (HRQoL), an important target for therapeutic intervention. Impaired iron homeostasis may be one mechanism underlying the poor physical condition of CHF patients. This detailed subanalysis of the previously published FAIR-HF study evaluated baseline HRQoL in iron-deficient patients with CHF and the effect of intr

Two searches for supersymmetric particles in final states containing a same-flavour opposite-sign lepton pair, jets and large missing transverse momentum are presented. The proton-proton collision data used in these searches were collected at a centre-of-mass energy root s = 8TeV by the ATLAS detector at the Large Hadron Collider and corresponds to an integrated luminosity of 20.3 fb(-1). Two lept

This paper presents the models, analytical equations and results of analysis for determination of major cutting edge, orthogonal and normal clearance and rake angles, and cutting edge inclination angle. The analysis is carried for variable side and back rake angles used by the tool manufacturers and a corresponding variation of the geometry along the edge line for the case of round tools. The infl

Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) associated with waist circumference (WC) and waist-to-hip ratio (WHR) adjusted for BMI (WCadjBMI and WHRadjBMI), but it remains unclear whether these SNPs relate to change in WCadjBMI or WHRadjBMI with lifestyle intervention for weight loss. We hypothesized that polygenic scores (PS) comprised of 59 SNPs previou