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Bacterial modulation of host glycosylation - in infection, biotechnology, and therapy

Popular Abstract in Swedish Hur gör bakterier för att komma undan immunförsvaret? Vi har studerat hur en vanligt förekommande bakterie, grupp A streptokocker, gör för att undvika kroppens immunförsvar vid infektion. Vi har upptäckt enzymer som bidrar till bakteriens förmåga att undvika immunförsvaret genom att avväpna antikroppar. De bakteriella enzymerna kan användas i bioteknisk industri och eveA majority of the proteins of the immune system are glycosylated and the glycans of IgG are essential for its functionality. Bacteria display enzymes that modulate the glycans of the immune system to weaken the host defense and favor bacterial survival. In this thesis we aimed at exploring bacterial modulation of host glycosylation in infection and to evaluate the usefulness of bacterial enzymes i

BspK, a serine protease from the predatory bacterium Bdellovibrio bacteriovorus with utility for analysis of therapeutic antibodies

The development of therapeutic and diagnostic antibodies is a rapidly growing field of research, being the fastest expanding group of products on the pharmaceutical market, and appropriate quality controls are crucial for their application. We have identified and characterized the serine protease termed BspK (Bdellovibrio serine protease K) from Bdellovibrio bacteriovorus and here show its activit

Two major classes in the M protein family in group A streptococci

The M protein family of molecules in the group A streptococcus comprises a number of cell surface proteins that interact with the immune system of the host. One of the proteins in this family is the IgA receptor Arp4, which has C repeats similar to those that characterize the known M proteins. The streptococcal strain expressing Arp4 also expresses a second immunoglobulin-binding protein, Mrp4, wh

Investigation on the effects of fly ash particles on the thermal radiation in biomass fired boilers

Ash is produced in combustion of biomass. Sonic part of this matter is called fly ash and is carried by the flow and causes not only air pollution and erosion, but also call affect the thermal radiation. The effects of fly ash particles oil the thermal radiation are considered ill this investigation. By analyzing sampled data in all electrostatic filter, a realistic particle size distribution is f

New perspectives on complement mediated immunotherapy

Tumor-specific monoclonal antibodies (mAbs) offer several modes of tumor cell killing, from direct cytotoxic activity to indirect mechanisms employing the host immune system, particularly its innate branch. The latter effector functions seem to dominate among clinically approved anti-cancer mAbs and major efforts are being undertaken by both academia and the pharmaceutical industry with the aim to

Jacobæus symposium

21 oktober 2024 12:00 till 17:15 | Seminarium The Jacobæus Prize is the oldest prize of the Novo Nordisk Foundation. It was established in 1939 to commemorate the Swedish professor Hans Christian Jacobæus. The purpose of the prize is to promote medical research and is awarded annually to a distinguished international researcher who is invited to give a lecture on his or her research on a topic wit

https://www.lu.se/evenemang/jacobaeus-symposium - 2025-11-06

Full Program

Conference and seminars: Peer support and Experiential knowledge in higher education Below you'll find the full program for the conference Peer Support and Experiential Knowledge, 13-15 May 2024. Monday 13 May, Conference Day9.00 – 10.00 Coffee and registration, Room: Entrence hall, School of Social Work, Allhelgona kyrkogata 8 (Gamla Köket).10.00 – 10.30 Welcome, Room: Edens Aula.10.30 – 11.00 Ke

https://www.soch.lu.se/full-program - 2025-11-05

Hösttermin 2024

Practical information for students an employees of Malmö Art Academy. Below you find important dates and documents for the semester ahead. Duration of the FALL semester 2024-09-02 - 2025-01-19  Duration of the SPRING semester 2025-01-20 - 2025-06-08  Midterm review week 36-45 (10 weeks = 50% of fall semester)  Deadline course suggestions for spring 2025: TBD    NSE= New Student Exhibition    Week

https://www.khm.lu.se/hosttermin-2024 - 2025-11-05

Verksamhetsberattelse 2019 for ebsco systems nordic user group

Verksamhetsberättelse 2019 för EBSCO Systems Nordic User Group Vid EBSCO Systems Nordic User Groups årsmöte 2019-04-04 i Göteborg valdes följande styrelsemedlemmar: ordförande Cilla Öhnfeldt, Stockholms universitetsbibliotek (omval), Ellen Åberg, Chalmers bibliotek (nyval), Eva Sejmyr, Linköpings universitetsbibliotek (omval), Stellan Klint, Skånes universitetssjukhus bibliotek (omval), Linda Tryg

https://www.ub.lu.se/sites/ub.lu.se/files/verksamhetsberattelse_2019_for_ebsco_systems_nordic_user_group.pdf - 2025-11-06

Mven15 schema 0

Prel.Schema MVEN015 - Klimatförändringen - vetenskap och samhälle Höstterminen 2014 OBS Alla starttider med kvart utom tentamen! Kurstid: - Kurschef: Niklas Vareman Lärare: JS Johannes Stripple LB Lars Bärring MLL Maj-Lena Linderson NV Niklas Vareman KL Karl Ljung EA Elina Andersson TG Terese Göransson JAO Johanna Alkan Olsson WD Wilhelm Dubber DH David Harnesk SB Sara Brogaard LN Lars J Nilsson J

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven15_schema_0.pdf - 2025-11-06

06032016 679 23 aronsson phn 2013

untitled Public Health Nutrition: 16(8), 1390–1402 doi:10.1017/S1368980013000293 Use of dietary supplements in pregnant women in relation to sociodemographic factors – a report from The Environmental Determinants of Diabetes in the Young (TEDDY) study Carin Andrén Aronsson1,*, Kendra Vehik2, Jimin Yang2, Ulla Uusitalo2, Kristen Hay3, Gesa Joslowski4, Anne Riikonen5, Lori Ballard2, Suvi M Virtanen

https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_23_aronsson_phn_2013.pdf - 2025-11-06

Verksamhetsberattelse 2018 for ebsco systems nordic user group

Verksamhetsberättelse 2018 för EBSCO Systems Nordic User Group Vid EDS Nordic User Groups årsmöte 2018-03-15 i Malmö bestämdes det att föreningen skulle byta namn till EBSCO Systems Nordic User Group. Det nya namnet beskriver bättre föreningens syfte och att medlemmarna ska kunna lyfta frågor kring fler EBSCO-system än enbart EDS. Vid årsmötet valdes också följande styrelsemedlemmar: ordförande Ci

https://www.ub.lu.se/sites/ub.lu.se/files/verksamhetsberattelse_2018_for_ebsco_systems_nordic_user_group.pdf - 2025-11-06

Publication In EMBO Journal

Activation of endogenous retroviruses during brain development causes an inflammatory response Article Activation of endogenous retroviruses during brain development causes an inflammatory response Marie E Jönsson1 , Raquel Garza1 , Yogita Sharma1, Rebecca Petri1 , Erik Södersten2, Jenny G Johansson1, Pia A Johansson1 , Diahann AM Atacho1, Karolina Pircs1 , Sofia Madsen1, David Yudovich3, Ramprasa

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/2021-03/publication%20in%20EMBO%20journal.pdf - 2025-11-06

The 5 ' Region of the MSH2 gene involved in hereditary non-polyposis colorectal cancer contains a high density of recombinogenic sequences

MSH2 rearrangements are involved in approximately 10% of hereditary non,polyposis colorectal cancer (HNPCC) families, and in most of the rearrangements, exon I is deleted. We scanned by quantitative multiplex polymerase chain reaction (PCR) of short fluorescent fragments (QMPSF) 200 kb of genomic sequences upstream of the MSH2 transcription initiation site in 21 HNPCC families with exon I deletion