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pnas201006568 11602..11607 Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors Rohit Sachdevaa, Marie E. Jönssona, Jenny Nelandera, Agnete Kirkebya, Carolina Guibentifa, Bernhard Gentnerb, Luigi Naldinib, Anders Björklunda, Malin Parmara, and Johan Jakobssona,1 aDepartment of Experimental Medical Sciences, Wallenberg Neuroscience Center,

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/11602.full_.pdf - 2026-07-20

Background. Neutrophils from patients with chronic kidney disease (CKD) are dysfunctional and thus a contributing factor to the risk of infections. The mechanisms for leucocyte dysfunction in CKD are not fully understood. It is known that lipopolysaccharide (LPS) activates transcription of several genes encoding proinflammatory cytokines. We therefore aimed to study the effect of LPS on neutrophil

Background: Staff who plan and organize day center activities may need to observe the attendees’ performance and progression. This led us to develop a tool for that purpose, termed General Occupational Engagement in people with Severe mental illness (GOES). The aim was to investigate its psychometric properties in terms of factor structure, internal consistency, corrected item-total correlations (

Mother tongue tuition (MTT) has been part of the Swedish educational system since 1977, with now almost 30 per cent of elementary school students eligible for the subject. With an increasingly globalized world, as well as expectations from the EU of all their member states’ citizens learning at least three languages, MTT could work as a means to meet the goal of a more linguistically knowledgeable

pnas201006568 1..6 Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors Rohit Sachdevaa, Marie E. Jönssona, Jenny Nelandera, Agnete Kirkebya, Carolina Guibentifa, Bernhard Gentnerb, Luigi Naldinib, Anders Björklunda, Malin Parmara, and Johan Jakobssona,1 aDepartment of Experimental Medical Sciences, Wallenberg Neuroscience Center, Lund Uni

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/sachdeva_et_al_pnas_2010.pdf - 2026-07-20

Numerous Neoproterozoic mafic dykes, referred to as the Dashigou swarm, are identified in the central and southeastern parts of the North China craton (NCC). They are 305-010 degrees trending dykes, with widths of similar to 10-100 m and exposed lengths of several to >10 km. Precise U-Pb isotope dilution thermal ionization mass spectrometry (ID-TIMS) measurements on baddeleyite grains separated fr

untitled Factors associated with longitudinal food record compliance in a paediatric cohort study Jimin Yang1,*, Kristian F Lynch1, Ulla M Uusitalo1, Kristina Foterek2, Sandra Hummel3, Katherine Silvis4, Carin Andrén Aronsson5, Anne Riikonen6, Marian Rewers7, Jin-Xiong She4, Anette G Ziegler3, Olli G Simell8, Jorma Toppari9, William A Hagopian10, Åke Lernmark5, Beena Akolkar11, Jeffrey P Krischer1

https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_47_yang_phn_2015.pdf - 2026-07-20

PURPOSE: Proactive management of type 2 diabetes is important for restoring beta-cell function and improving sustained blood glucose control. Evidence on quality of diabetes care in Ethiopia is inadequate.METHOD: Facility-based cross-sectional study was conducted to assess level of quality of care provided to adult type 2 diabetes patients at three public hospitals in Gamo Gofa Zone, Southern Ethi

Purpose: Hematoma volume is the strongest predictor of patient outcome after intracerebral hemorrhage (ICH). The aim of this study was to validate novel fully automated software for quantification of ICH volume on non-contrast computed tomography (CT). Methods: The population was defined from the Swedish Stroke Register (RS) and included all patients with an ICH diagnosis during 2016–2019 in Regio

Objectives: To assess if improvement of working conditions related to heat stress was associated with improved kidney health outcomes among sugarcane harvest workers in Chichigalpa, Nicaragua, a region heavily affected by the epidemic of chronic kidney disease of non-traditional origin. Methods: Based on our findings during the 2017-2018 harvest (harvest 1), recommendations that enhanced the rest

Technological and policy solutions for transitioning to a fossil-free society exist, many countries could afford the transition, and rational arguments for rapid climate action abound. Yet effective action is still lacking. Dominant policy approaches have failed to generate action at anywhere near the rate, scale or depth needed to avoid potentially catastrophic futures. This is despite 30 years o

Introduction: After extensive pelvic surgery for cancer two flap types are used at Skåne University Hospital (SUS), Sweden for perineal reconstruction: vertical rectus abdominis myocutaneous flap and gluteal flap with or without vaginal reconstruction. The objective was to study the long-term outcomes in patients treated for advanced pelvic cancer receiving a flap. Method: Patients with pelvic can

The Cretaceous–Palaeogene (K–Pg) mass extinction about 66 Ma ago was one of Earth’s largest mass extinction events. The demise of calcifiers, among others, influenced biogeochemical cycles and changed the conditions for carbonate depo sition in the global ocean. This study addresses the sedimentology and carbonate microfacies of the Cerithium Limestone Member of the Rødvig Formation within the ren

Background: Young adults with autism often have problems with body awareness, also acknowledged by physiotherapists. This may interfere with various physiological and psychological responses, expressed in reduced movement quality. Basic Body Awareness Therapy (BBAT) may be suitable to address these difficulties, to enhance body awareness and movement quality to manage everyday life. Body Awareness

Magnetomotive ultrasound is an emerging technique that enables detection of magnetic nanoparticles. This has implications for ultrasound molecular imaging, and potentially addresses clinical needs regarding determination of metastatic infiltration of the lymphatic system. Contrast is achieved by a time-varying magnetic field that sets nanoparticle-laden regions in motion. This motion is governed b

INTRODUCTION: Intracranial haemorrhage (ICH) is the most serious complication in infants and children with severe congenital bleeding disorders causing substantial mortality and long-term neurological morbidity. The neonatal period carries the highest risk, particularly in severe haemophilia and rare factor deficiencies. We review the epidemiology, risk factors, prevention, recognition, management

Background Colorectal cancer (CRC) remains a major global health challenge with high morbidity and mortality despite advances in detection and treatment. Dietary polyphenols are secondary metabolites widely found in plant-derived foods and beverages, and have gained attention for their potential in CRC prevention and therapy due to their diverse biological activities. Methods This review synthesiz

Objective: To evaluate the influence of implant and prosthetic components on peri-implant tissue health. A further aim was to evaluate peri-implant soft-tissue changes following surgical peri-implantitis treatment. Materials and methods: Group discussions based on two systematic reviews (SR) and one critical review (CR) addressed (i) the influence of implant material and surface characteristics on

Despite the anticipated benefits of smart home technology (SHT) to support older adults' engagement in meaningful activities, barriers to the adoption of SHT have been identified. While research in the field of technology is surging, research on older adults playing an active role in designing and developing SHT to enhance usability is lacking. It is important to co-develop solutions to place olde

This study investigates strategies for igniting hydrogen in compression ignition engines, a process traditionally hindered by hydrogen’s high ignition temperature. In conventional dual-fuel engines, a small diesel pilot is often used to ignite hydrogen, taking advantage of diesel’s lower ignition temperature to initiate combustion. While effective, this approach introduces carbon emissions, limiti