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Background and aims: Heart transplantation is the preferred treatment for selected patients with end stage heart failure. Kidney function often declines after heart transplantation. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) slow the decline in eGFR in different populations. However, the effect of SGLT2i on kidney function in heart transplant recipients is unknown. Methods: The Dapaglifloz

Molecular subtyping has been a major focus of bladder cancer research over the past decade. Despite many promising associations with clinical outcomes and treatment response, its clinical impact has yet to be defined. As part of the 2022 International Society of Urological Pathology Conference on Bladder Cancer, we reviewed the current state of the science for bladder cancer molecular subtyping. O

Brazil’s electricity system remains profoundly shaped by its historical reliance on hydropower, which has repeatedly exposed the country to crises during periods of drought. This thesis examines the water–energy nexus in Brazil from a temporal perspective, showing how past legacies, present vulnerabilities, and future pathways are interconnected. A review of the literature reveals that nexus studi

Background and objective: Prostate cancer (PC) is the second most common cancer and a leading cause of death among males. In this systematic review we evaluated cohort studies and randomized controlled trials (RCTs) on the relationship between dietary patterns and PC risk, progression, mortality, and biomarkers. Methods: A systematic search of MEDLINE, Embase, and Cochrane Central was conducted th

BACKGROUND: Child abuse continues to pose a significant threat to children's health. The repercussions of abuse are profound, impacting the child's physical, social, and emotional well-being, with potential long-term effects that may extend into adulthood. To assist in identifying health concerns in children associated with exposure to physical abuse, a health questionnaire was developed to be use

This thesis takes its departure in the critical marketing scholarship where the scholars diverge into conflicting perspectives—the Market either being un-politicizing or de-politicizing. The aim of the research, therefore, was to contribute to the critical marketing stream of literature by reconciling these theoretical tensions. We conducted this research with an empirical case of a contemporary c

Global rising temperatures is impacting species interactions worldwide including those between host and parasites. A long-term study on a population of blue tits (Cyanistes caeruleus) linked increases in avian malaria parasites to rising temperatures. Understanding the consequences that these increases in avian malaria parasites are causing is vital. Therefore, data from the past 28 years on this

Efforts to regulate transnational corporations in the context of human rights are not new. They traced back to the early 1970s, when the United Nations first initiated attempts to study the impact of transnational corporations on the international development process and proposed a United Nations Code of Conduct on Transnational Corporations, an initiative that ultimately stalled. A renewed attemp

This thesis analyses the structural limitations of the prevailing entitlement-based framework of international human rights law (IHRL), particularly in pluralistic and multicultural societies, and evaluates whether integrating duties alongside existing rights, a duty-infused reconceptualization, can address those limitations or not? The study draws its primary motivation from a structural crisis i

Industrial pasteurisation is a heat-intensive process with significant potential for decarbonisation. This study investigates how open-source Modelica libraries can be adapted for industry, especially for food industry, and integrated to replace fossil-based thermal systems. Investigations are done to evaluate models of heat pumps, thermal energy storage, specifically the stratified tank, and sol

The effects of subthalamic nucleus deep brain stimulation (STN-DBS) on anxiety in Parkinson’s disease (PD) are understudied. We identified clinical predictors of STN-DBS effects on anxiety in this study. In this prospective, open-label, multicentre study, we assessed patients with anxiety undergoing STN-DBS for PD preoperatively and at 6-month follow-up postoperatively. We assessed the Hospital An

Context. Gravitational waves from black-hole (BH) merging events have revealed a population of extra-galactic BHs residing in short-period binaries with masses that are higher than expected based on most stellar evolution models-And also higher than known stellar-origin black holes in our Galaxy. It has been proposed that those high-mass BHs are the remnants of massive metal-poor stars. Aims. Gaia

OBJECTIVE: The objective of this study was to provide novel comparative insights on the contributions of injury deaths to the changes in sex gaps in life expectancy (SGLE) and sex gaps in life disparity (SGLD) across Nordic countries.STUDY DESIGN: Retrospective demographic analysis of aggregated mortality data.METHODS: To compute life expectancy (LE)/life disparity (LD), annual data on age- and se