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Fresh frozen plasma reduces thrombin formation in newborn infants

BACKGROUND: Newborn infants undergoing intensive care are at risk of bleeding and thrombotic complications. Fresh frozen plasma (FFP) is used in hope of preventing these complications, despite poorly defined effects on the coagulation system and lack of proven clinical efficacy. OBJECTIVES AND METHODS: We prospectively evaluated coagulopathy and the effect of standardized amount of FFP transfusion

Lunds-universitets-magasin-6-2009

Genterapi mot Parkinsons LUM Lunds universitets magasin | Nr 6 | 2009 det gLobaLa kLassrUMMet Insektsforskare kämpar för stubbarna 2 LUM nr 6 | 2009 PUss På dig doktorn! LUM nr 6 | 2009 3 Solen svek inte doktorspromotionen i år hel- ler. Den lyste över 233 nya doktorer, 18 he- dersdoktorer och 14 jubeldoktorer. Till dessa kom kransflickor, fanbärare, musiker, an- höriga och intresserade lundabor.

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-6-2009.pdf - 2026-06-07

Decreased plasma concentrations of apolipoprotein M in sepsis and systemic inflammatory response syndromes

Introduction: Apolipoprotein M (apoM) is present in 5% of high-density lipoprotein (HDL) particles in plasma. It is a carrier of sphingosine-1-phosphate (S1P), which is important for vascular barrier protection. The aim was to determine the plasma concentrations of apoM during sepsis and systemic inflammatory response syndrome (SIRS) and correlate them to levels of apolipoprotein A-I (apoA1), apol

Verksamhetsberättelse CASE 2025

Nationella forskarskolan om åldrande och hälsa Verksamhetsberättelse 2025 CASE - Centre for Ageing and Supportive Environments Foto: Kennet Ruona Centre for Ageing and Supportive Environments Verksamhetsberättelse 2025 2 Förord Med denna verksamhetsrapport ger vi en kortfattad sammanfattning av den verksamhet som bedrivits inom Centre for Ageing and Supportive Environments (CASE) under 2025. CASE

https://www.case.lu.se/sites/case.lu.se/files/2026-03/Verksamhetsber%C3%A4ttelse%20CASE%202025.pdf - 2026-06-07

Evaluation of wire-line well logs from the borehole Kyrkheddinge-4 by comparison to measured core data

Populärvetenskaplig sammanfattning: Utvärdering av borrhålsloggar. Syftet med detta examensarbete var att göra en utvärdering av wireline borrhålsloggar från borrhålet Kyrkheddinge-4, 3 km öster om Staffanstorp i Skåne. Den undersökta delen av borrhålet Kyrkheddinge-4 befinner sig inom den potentiella reservoarsandstenen, Lundasandstenen. Wireline borrhålsloggar är geofysiska verktyg som används This study is an evaluation of formation characteristics, as derived from wire-line well logs, of the Lund Member in the borehole Kyrkheddinge-4, 3 km east of Staffanstorp, Skåne, Sweden, through the comparison to measured core data. The purpose is to assess the feasibility of using some of the porosity and permeability equations and cross-plots derived for the investigated section and applying th

Improved In Vitro Culture of Plasmodium falciparum Permits Establishment of Clinical Isolates with Preserved Multiplication, Invasion and Rosetting Phenotypes

To be able to robustly propagate P. falciparum at optimal conditions in vitro is of fundamental importance for genotypic and phenotypic studies of both established and fresh clinical isolates. Cryo-preserved P. falciparum isolates from Ugandan children with severe or uncomplicated malaria were investigated for parasite phenotypes under different in vitro growth conditions or studied directly from

The Relative Importance of Fecal and Urinary Excretion of Perfluorooctane Sulfonic Acid and Perfluorooctanoic Acid after High Exposure - An Observational Study in Ronneby, Sweden

BACKGROUND: Many poly- and perfluoroalkyl substances (PFAS) are persistent and have long half-lives in the human body. However, there are limited data on the different routes of elimination. Most pharmacokinetic models assume that the urinary route dominates.OBJECTIVES: Our aim was to investigate the relative importance of fecal and urinary elimination for linear perfluorooctane sulfonic acid (L-P

CAG repeat number is not inversely associated with androgen receptor activity in vitro.

A negative linear association between androgen receptor (AR) function and the CAG repeat numbers is generally assumed. However, in vivo data concerning the association between CAG number and androgenic effects have been conflicting. Since former in vitro studies mostly have been based on extreme CAG lengths and reporter-systems containing viral promoters, the objective of this study was to investi

Intraoperative Cytology for Video-Assisted Thoracic Surgery : A Quality Improvement Analysis

Background: Frozen section is a standard of care procedure during thoracic surgery when an immediate diagnosis is needed. An alternative procedure is intraoperative cytology. Video-assisted thoracic surgery is currently widely used for thoracic surgical procedures. The aim of this study was to assess intraoperative cytology together with frozen section for accuracy, turnaround time, and total resp

Consumption of fruits, vegetables and fruit juices and differentiated thyroid carcinoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Fruit and vegetable (F&V) intake is considered as probably protective against overall cancer risk, but results in previous studies are not consistent for thyroid cancer (TC). The purpose of this study is to examine the association between the consumption of fruits, vegetables, fruit juices and differentiated thyroid cancer risk within the European Prospective Investigation into Cancer and Nutr

Patient satisfaction after unilateral oncoplastic volume displacement surgery for breast cancer, evaluated with the BREAST-Q™

Background: Oncoplastic breast-conserving surgery allows larger resections in unfavorable locations, with an improved chance of preserving esthetics. Indications and timing for potential contralateral surgery to obtain symmetry are not clear. The aim of this study was to evaluate patient satisfaction after unilateral oncoplastic volume displacement surgery, to investigate potential risk factors fo

Primary screening for increased fracture risk by the FRAX® questionnaire—uptake rates in relation to invitation method

Summary: The aim of the study was to evaluate the feasibility and most efficient way of offering middle-aged Swedish women a primary fracture screening program via a questionnaire. Two out of five invited women returned the FRAX questionnaire and those contacted directly by mail were most prone to respond. Purpose: Osteoporosis and its associated fractures are increasing, and this study aims to ex

Responsiveness of the patient-specific Canadian occupational performance measure and a fixed-items activity limitations measure in patients with dupuytren disease

Background: Patients with Dupuytren disease experience various activity limitations. Treatment aims to reduce finger joint contractures to improve hand function and activity performance. For assessing improvement different patient-centered measures have been used. The Canadian Occupational Performance Measure (COPM) was developed as an interview-based outcome measure to detect changes over time in

Factors important for health-related quality of life in men and women: The population based SCAPIS study

IntroductionHealth-related quality of life (HRQoL) is essential for human wellbeing, influenced by a complex interplay of factors, and is reported lower in women than men. We aimed to evaluate which factors were the most important for HRQoL in a middle-aged general population.MethodsThis was a cross-sectional, multi-centre study of 29,212 men (48%) and women (52%) aged 50–64 in the general populat

Implementation and applications of robotic surgery within gynecologic oncology and gynecology; Analysis of the first thousand cases

Objective. To describe the effects of implementing a robotic surgical program within gynecologic oncology and gynecology at a tertiary referral hospital. Design: Prospective study. Setting: University Hospital, Lund and Lund University, Sweden. Methods. Based on prospective data retrieved for all patients, we evaluated intraoperative times, estimated blood loss, rate of conversion and rate of intr

No excess harms from sustained-release morphine : A randomised placebo-controlled trial in chronic breathlessness

Objectives: We aimed to identify and evaluate: (1) treatment-emergent adverse events (TEAE (worse or new since baseline)) and the subgroup of severe TEAEs in a placebo-controlled 7-day randomised trial of regular, low-dose, sustained-release oral morphine for chronic breathlessness and (2) clinical characteristics associated with TEAE. Methods: Safety analysis of trial data. Adults with chronic br

Antimicrobial use at the end of life : a retrospective cohort study

Antibiotic resistance poses a global threat. Antibiotics are administered to 80-90% of terminally ill patients but evidence of their effectiveness in improving survival or symptom relief at the end of life (EOL) is scarce. To determine the proportion of deceased patients that continue antibiotic treatment after documented EOL discussion and the decision to prioritise symptom relief over active tre

On the Hausdorff measure and the Kakeya Conjecture in R^2

Fraktaler är mängder som har detaljer på varje skala. För många sådana mängder är mått som area och längd inte tillräckligt som en beskrivning av storlek. Ta exempelvis den inverterade Koch-kurvan. Kurvan skapas genom att vi tar bort mittdelen av varje sidlängd i omkretesen av en triangel och byter ut den med de andra två sidorna av en liksidig triangel baserat på denna mittdel. Upprepar vi dennaThe purpose of this thesis is to cover the definition and basic properties of the Hausdorff measure and treat the proofs of Davies and Cordoba of the Kakeya conjecture in R^2. The conjecture states that any compact set in R^2 containing a line in every direction has Hausdorff dimension 2. Using mainly basic measure theory we construct the Hausdorff measure and develop relevant theorems, such as Ma