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Rat models are useful for studies of the pathogenesis of rheumatoid arthritis (RA) since rats are extraordinarily sensitive to induction of arthritis with adjuvants. Injection of not only the classical complete Freund's adjuvant but also mineral oil without mycobacteria and pure adjuvants such as pristane and squalene, induce severe arthritis in many rat strains. Models like pristane-induced arthr
Adolphson has grown up in the shadows (and light) of Evert Taube litterarily since he from childhood been a friend of Evert Taubes son Sven Bertil. He has gone deep into the songs and poetry of Evert Taube. This study focuses on the phychological impact Adolphson inherited from Taube as well as the darker sides of the personality
Popular Abstract in Swedish Bränder utgör en risk för människor p.g.a. värmen samt de utsläpp som produceras från en brand. Man kan tydligt se från brandstatistik, att det faktiskt är brandgaserna som dödar och skadar många människor. Vidare produceras från bränder ämnen som inte har en direkt effekt, men som i stället kan ge indirekta skador. Vissa av dessa ämnen är kända för att ha en långsiktigAccidental fires represent a risk for people from the heat and fire effluents produced. It is clear from fire statistics that it is, in fact, the toxic gases that kill and injure many fire victims. Further, there are a number of compounds that are readily produced in fires, which have important sublethal effects on humans. Some of those compounds are known to have a long-term effect on people, and
Voltage and dephasing probes introduce incoherent inelastic and incoherent quasielastic scattering into a coherent mesoscopic conductor. We discuss in detail the concepts of voltage and dephasing probes and develop a full-counting statistics approach to investigate their effect on the transport statistics. The formalism is applied to several experimentally relevant examples. A comparison of differ
The article explores the relation between monotheism and intolerance: are monotheistic religions more "intolerant" than are non-monotheistic religions? Is monothesim per definitionem exclusive and intolerant? The article seeks to indicate some of the ways in which monotheistic belief can both hinder and further improved interreligious relations. To what extent do monotheists today take responsibil
The Swedish auxiliary "lär" may have been established at the end of the 15th century in Swedish. Its two possible origins are discussed from phonological, morphological and semantic aspects. Possible stages in its develpment are identified and discussed as cases of grammaticalization.
Essä om filosofiska idéer i Éric Rohmers Tre män och en kärlek.
The object of this paper is to develop a discussion of territoriality in the built environment as a way of dealing with issues of accessibility and the public nature of urban space. A discussion of territoriality makes it possible to deal with issues of spatial control and access in detail, as well as to maintain some of the complexity in the discussion by refraining from solely analysing these is
Software architecture, the underlying structure to a software system, is an asset which can be invested in. Such investments can later be capitalized on in the form of e.g. increased flexibility and enhanced maintainability. These benefits may be gained in a system developed in one project, but are much more visible in a strategic perspective when several projects share resources. Architectural de
Being a caregiver with responsibility for someone with reduced health compared with not being a caregiver may mean different views of life satisfaction. Knowledge of what leads to reduced life satisfaction in caregivers may be helpful in interventions. Informal caregivers gainfully employed or not, aged 50–89 years, were studied with regard to life satisfaction depending on the extent of caregivin
The heterogeneity of the components of proteoglycan aggregates, their stoichiometry within the aggregate and the aggregates' stability was investigated in normal human articular cartilage specimens (age-range newborn to 63 years). Proteoglycans were extracted from tissue by sequentially extracting them with PBS alone, PBS containing oligosaccharides of hyaluronan, and PBS containing solutions of i
The evolution of human immunodeficiency virus type 1 (HIV-1) coreceptor use has been described as the acquisition of CXCR4 use linked to accelerated disease progression. However, CXCR4-using virus can be isolated only from approximately one-half of individuals with progressive HIV-1 disease. The other half continue to yield only CCR5-using viruses (R5 phenotype) throughout the course of disease. I
1. We measured the abundance and biomass of filter-feeding microcrustacean zooplankton and calculated their grazing impact on phytoplankton biomass during summer in five shallow, mesotrophic to eutrophic lakes. For three of the lakes data exist both from years with dense submerged vegetation and low turbidity (the clearwater state), as well as from years characterised by sparse vegetation and high
Purpose of review To examine the development of recombinant FVIIa (rFVIIa); a new concept of inducing hemostasis. It was developed for use in hemophilia patients with inhibitors against FVIII or FIX with the vision to provide these patients with a therapeutical option to be used instead of FVIII or FIX. For the first time it was shown that pharmacological doses of FVIIa induced hemostasis. Recent
