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Aortic aneurysms are rare manifestations in children with tuberous sclerosis complex (TSC) with life threating implications. Although an association between TSC, aortic and other aneurysms has been recognized, mechanistic insights explaining the pathophysiology behind aneurysm development and genetic aberrations in TSC have so far been lacking. Here, we summarize existing knowledge on aneurysms in
Spermatozoa motility in freshwater and marine fish is mainly controlled by the difference in osmotic pressure. Specifically, zebrafish (Danio rerio) spermatozoa undergo hypoosmotic shock due to the decrease in extracellular potassium, which leads to membrane hyperpolarization and activation of flagellar motility. Previous studies have concluded that motility activation has a negative effect on the
Objective:To assess cardiovascular effects of in-utero HIV and antiretroviral treatment (ART) exposure on offspring of HIV-positive mothers in Ethiopia.Design:HIV-positive and HIV-negative pregnancies were identified from a prospective cohort of women recruited at their first antenatal care visit in Ethiopia, using a nested case-control design.Methods:Fetal standard ultrasound and echocardiography
Background: The majority of individuals with dementia will suffer from behavioral and psychological symptoms of dementia (BPSD). These symptoms contribute to functional impairment and caregiver burden. Objective: To characterize BPSD in Alzheimer's disease (AD), vascular dementia (VaD), mixed (Mixed) dementia, Parkinson's disease dementia (PDD), dementia with Lewy bodies (DLB), frontotemporal deme
Background: Asthma and chronic obstructive pulmonary disease (COPD) are chronic conditions where relational continuity of care, as in regularly meeting the same health care provider, creates opportunities for monitoring and adjustment of treatment based on an individual's changing needs, potentially affecting quality of delivered care. The aim of this systematic review was to investigate the effec
BACKGROUND: To identify factors related to reproductive history and weight change associated with first incident fracture in middle-aged women.METHODS: In total, 18,326 women from the Malmö Diet and Cancer study were included in this prospective population-based cohort study. Participants were included 1991-1996 and followed to 2016. Using data from the National Patient Registry, linked with every
Heart failure (HF) affects 64 million people worldwide. Despite advancements in prevention and therapy, quality of life remains poor for many HF patients due to associated target organ damage. Pulmonary manifestations of HF are well-established. However, difficulties in the treatment of HF patients with chronic lung phenotypes remain as the underlying patho-mechanistic links are still incompletely
Different aspects of the novel have changed at a different pace. If one compares modernist novels with those of a 100 years previously, not only is an inward turn noticeable but also an outward turn: the sky, for example, is much more present. This change does not, however, coincide with the Victorian-modernist divide but rather comes when the influence of romantic poetry reaches the novel. This c
Every EU country must adapt its national regulations to the common EU and ECHR standards. There is, however, a certain discretion to apply the EU standards into national legislation. For those in need of protection, is Sweden more or less generous in comparison to the EU’s minimum rules?This study examines Swedish asylum legislation from a European perspective. Although EU Member States are bound
BackgroundThe knowledge about striatal hand deformities (SHD) in Parkinson’s disease (PD), has recently increased but need more attention due to their early impact on dexterity. The focus of clinical studies has been on the staging of SHD severity and neurological features. However, a hand surgical perspective has not been considered.ObjectivesOur purpose was to examine SHD in patients with PD usi
The particular properties of argumental compounds in Italian pose interesting theoretical challenges, and investigations of possible syntactic operations within this type of complex words have resulted in conflicting conclusions. Regarding compoundinternal anaphora, some researchers exclude the possibility that pronouns can refer to the non-head, while others do not. However, these findings have b
Inledning till översättningsvolymen "The Forbidden Door" som innehåller dikter av den svenske poeten Lasse Söderberg (f. 1931), översatta till engelska av Lars Gustaf Andersson och Carolyn Forché.
The dramatic improvements in Boolean satisfiability (SAT) solving since the turn of the millennium have made it possible to leverage state-of-the-art conflict-driven clause learning (CDCL) solvers for many combinatorial problems in academia and industry, and the use of proof logging has played a crucial role in increasing the confidence that the results these solvers produce are correct. However,
