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Comprehensive ecosystem model-data synthesis using multiple data sets at two temperate forest free-air CO2 enrichment experiments: Model performance at ambient CO2 concentration

Free-air CO2 enrichment (FACE) experiments provide a remarkable wealth of data which can be used to evaluate and improve terrestrial ecosystem models (TEMs). In the FACE model-data synthesis project, 11 TEMs were applied to two decadelong FACE experiments in temperate forests of the southeastern U.S.the evergreen Duke Forest and the deciduous Oak Ridge Forest. In this baseline paper, we demonstrat

A Benign Vascular Tumor With a New Fusion Gene: EWSR1-NFATC1 in Hemangioma of the Bone.

The EWSR1 gene in chromosome band 22q12 is a promiscuous fusion partner involved in a vast array of tumors characterized by gene fusions. In this study, we report the finding of a new fusion gene, EWSR1-NFATC1, in a hemangioma of the bone; genetic rearrangements have not previously been described in this tumor type. Chromosome banding analysis showed a t(18;22)(q23;q12) translocation as the sole c

Humic substances cause fluorescence inhibition in real-time PCR.

Real-time PCR (qPCR) is the cornerstone of DNA analysis, enabling detection and quantification of minute nucleic acid amounts. However, PCR-based analysis is limited, in part, by the presence of inhibitors in the samples. PCR inhibition has been viewed solely as failure to efficiently generate amplicons, i.e. amplification inhibition. Humic substances (HS) are well known inhibitors of PCR amplific

Novel High-Performing Single-Pressure Combined Cycle With CO2 Capture

The European electric power industry has undergone considerable changes over the past two decades as a result of more stringent laws concerning environmental protection along with the deregulation and liberalization of the electric power market. However, the pressure to deliver solutions in regard to the issue of climate change has increased dramatically in the last few years and has given rise to

Relative Quantification of Membrane Proteins in Wild-Type and Prion Protein (PrP)-Knockout Cerebellar Granule Neurons

Approximately 25% of eukaryotic proteins possessing homology to at least two trans membrane domains are predicted to be embedded in biological membranes. Nevertheless, this group of proteins is not usually well represented in proteome-wide experiments due to their refractory nature. Here we present a quantitative mass spectrometry-based comparison of membrane protein expression in cerebellar granu

Recombinant Tissue Plasminogen Activator in the Treatment of Neonates with Intracardiac and Great Vessels Thrombosis

Life-threatening intracardiac and great vessels thrombi are rare in neonates. Recombinant tissue plasminogen activator (rTPA) is used in adults to stimulate fibrinolysis and facilitate thrombus resolution. Its use in neonates, along with heparin, remains controversial because of potential risk of serious bleeding. We aim to present our experience with the use of thrombolytic agents in seven neonat

Legitimacy and reputation in the institutional field of food safety: A public relations case study.

The overall objective of this study is to examine how the institutional context of food safety affects and is affected by concerns for legitimacy and reputation. The paper employs a neo-institutional approach to analyzing the institutional field of food safety in a case study of a multinational food service provider where a tension between conflicting institutional logics implied a reputational ch

Use of tramadol in early pregnancy and congenital malformation risk.

Only few studies exist regarding the risk of a teratogenic effect of tramadol when used in early pregnancy. Using the Swedish Medical Birth Register, women (deliveries in 1997-2013) who had reported the use of tramadol in early pregnancy were identified. Maternal characteristics and concomitant drug use were analyzed. Among 1 682 846 women (1 797 678 infants), 1751 (1776 infants) had used tramadol

J/psi production and nuclear effects in p-Pb collisions at=5.02 TeV

Inclusive J/psi production has been studied with the ALICE detector in p-Pb collisions at the nucleon-nucleon center of mass energy = 5.02 TeV at the CERN LHC. The measurement is performed in the center of mass rapidity domains 2.03 < y (cms) < 3.53 and -4.46 < y (cms) < -2.96, down to zero transverse momentum, studying the mu (+) mu (-) decay mode. In this paper, the J/psi production cross sectio

Dimethylglycine Deficiency and the Development of Diabetes mellitus.

Experimental studies have suggested possible protective effects of dimethylglycine (DMG) on glucose metabolism. DMG is degraded to glycine through a DMG-dehydrogenase (DMGDH)-catalyzed reaction and this is the only known pathway for the breakdown of DMG in mammals. In this study we aimed to identify the strongest genetic determinant of circulating DMG concentration and to investigate its associati

Impact of optimized mixing heights on simulated regional atmospheric transport of CO2

The mixing height (MH) is a crucial parameter in commonly used transport models that proportionally affects air concentrations of trace gases with sources/sinks near the ground and on diurnal scales. Past synthetic data experiments indicated the possibility to improve tracer transport by minimizing errors of simulated MHs. In this paper we evaluate a method to constrain the Lagrangian particle dis

"Cittáslow". Eco-gastronomic heritage as a tool for destination development

In gastronomic tourism, Slow Food has gained considerable attention. Cittáslow, a network of towns, are working with qualitative local urban development, based on similar principles as Slow Food. This article studies how destination development and destination marketing is conducted in a cittáslow context. A study was conducted in three cittáslow towns in Northern Italy. All three towns worked amb

Time-dependent angular analysis of the decay B-s(0) -> J/psi phi and extraction of Delta Gamma(s) and the CP-violating weak phase phi(s) by ATLAS

A measurement of B-s(0) -> J/psi phi decay parameters, including the CP-violating weak phase phi(s) and the decay width difference Delta Gamma(s) is reported, using 4.9 fb(-1) of integrated luminosity collected in 2011 by the ATLAS detector from LHC pp collisions at a centre-of-mass energy root s = 7 TeV. The mean decay width Gamma(s) and the transversity amplitudes vertical bar A(0)(0)vertical ba

Spectral heterogeneity of QuickBird satellite data is related to fine-scale plant species spatial turnover in semi-natural grasslands

Abstract Question: Can satellite data be related to fine-scale species diversity and does the integrated use of field and satellite data provide information that can be used in the estimation of fine-scale species diversity in semi-natural grassland sites? Location: The Baltic Island of Oland (Sweden). Methods: Field work including the on-site description of 62 semi-natural grassland sites (repres

Supporting ‘future research leaders’ in Sweden: Institutional isomorphism and inadvertent funding agglomeration

The most recent fashion in the policy-level promotion of excellence in academic research seems to be the launching of funding programs directed to young and promising (postdoc level) researchers with the purpose of assisting them in establishing their own research profile at this allegedly crucial and fragile career stage. In the Swedish public research funding system, which is rather diversified

Trophic level changes of fishery catches in Lake Chaohu, Anhui Province, China: Trends and causes

Fishing activity has been suggested to affect food web structure and functioning of aquatic ecosystems. Based on changes of the mean trophic level index of fishery catch, the present study demonstrates long-term ecosystem impacts of fisheries in Lake Chaohu, a freshwater lake in Anhui Province, China. The decline of mean trophic level (MTL) in the last five decades, coupled with a dramatic increas

Randomized, Double-Blind, Dose-Finding Study for Tiotropium when Added to Olodaterol, Administered via the Respimat(®) Inhaler in Patients with Chronic Obstructive Pulmonary Disease.

Combining long-acting muscarinic antagonists (LAMAs) and long-acting β2-agonists (LABAs) is beneficial in chronic obstructive pulmonary disease (COPD), as the two classes of bronchodilator have complementary modes of action. The optimal dose for the fixed-dose combination of the LAMA tiotropium and the LABA olodaterol needed to be determined. In this phase II trial, the dose response of tiotropium

Structural and Biochemical Analyses of Glycoside Hydrolase Families 5 and 26 beta-(1,4)-Mannanases from Podospora anserina Reveal Differences upon Manno-oligosaccharide Catalysis

The microbial deconstruction of the plant cell wall is a key biological process that is of increasing importance with the development of a sustainable biofuel industry. The glycoside hydrolase families GH5 (PaMan5A) and GH26 (PaMan26A) endo-beta-1,4-mannanases from the coprophilic ascomycete Podospora anserina contribute to the enzymatic degradation of lignocellulosic biomass. In this study, P. an

Einstein@Home all-sky search for periodic gravitational waves in LIGO S5 data

This paper presents results of an all-sky search for periodic gravitational waves in the frequency range [50, 1190] Hz and with frequency derivative range of similar to[-20, 1.1] x 10(-10) Hz s(-1) for the fifth LIGO science run (S5). The search uses a noncoherent Hough-transform method to combine the information from coherent searches on time scales of about one day. Because these searches are ve