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Glutamate receptors are well-known actors in the central and peripheral nervous systems, and altered glutamate signaling is implicated in several neurological and psychiatric disorders. It is increasingly recognized that such receptors may also have a role in tumor growth. Here we provide direct evidence of aberrant glutamate signaling in the development of a locally aggressive bone tumor, chondro
Background: The purpose of this study was to examine whether a multidisciplinary intervention targeting drug-related problems, cognitive impairment, and discharge miscommunication could reduce readmissions in a general hospital population. Methods: This prospective, non-randomized intervention study was carried out at the department of general internal medicine at a tertiary university hospital. T
Orthostatic hypotension (OH) is a common cardiovascular disorder, with or without signs of underlying neurodegenerative disease. OH is diagnosed on the basis of an orthostatic challenge and implies a persistent systolic/diastolic blood pressure decrease of at least 20/10 mm Hg upon standing. Its prevalence is age dependent, ranging from 5% in patients <50 years of age to 30% in those >70 years of
Birds have remained the dominant model for studying the mechanisms of animal navigation for decades, with much of what has been discovered coming from laboratory studies or model systems. The miniaturisation of tracking technology in recent years now promises opportunities for studying navigation during migration itself (migratory navigation) on an unprecedented scale. Even if migration tracking s
The land-atmosphere exchange of methane (CH4) and carbon dioxide (CO2) in a high-Arctic wet tundra ecosystem (Rylek ae rene) in Zackenberg, north-eastern Greenland, was studied over the full growing season and until early winter in 2008 and from before snow melt until early winter in 2009. The eddy covariance technique was used to estimate CO2 fluxes and a combination of the gradient and eddy cova
Pressure drop and convective heat transfer characteristics of water and five alumina/water nanofluids of weight concentrations from 0.78% wt. to 7.04% wt. were experimentally investigated for both laminar flow and turbulent flow inside a double-pipe helically coiled heat exchanger. Effect of nanoparticles on the critical Reynolds number is negligible. A new correlation was developed for laminar fl
This study focused on older patients participating in a team meeting (TM) in a hospital ward in Sweden. A process had taken place on the ward, in which the traditional round had developed into a TM and understanding what participating in a TM means for the older patient is necessary for the development of care that facilitates older patient's participation. The aim of this study was to describe th
Next-generation sequencing of the V1-V2 and V3 variable regions of the 16S rRNA gene generated a total of 674,116 reads that described six distinct bacterial biofilm communities from both water meters and pipes. A high degree of reproducibility was demonstrated for the experimental and analytical work-flow by analyzing the communities present in parallel water meters, the rare occurrence of biolog
Particles, climate change, and health have thought-provoking interactions. Air pollution is one of the largest environmental problems concerning human health. On the other hand, aerosol particles can have a cooling effect on climate and a reduction of those emissions may result in an increased temperature globally, which in turn may have negative health effects. The objective of this work was to i
Network theory can be employed in two ways in archaeology: it can be used to analyse archaeological data, or it can be used to model a historical process for the purpose of simulating the data. This paper focuses on the first approach. In such analyses, similar archaeological contexts are often connected to form a similarity network. Similarity is treated as a proxy for social or causal relationsh
Is the cohomology of the classifying space of a p-compact group, with Noetherian twisted coefficients, a Noetherian module? In this paper we provide, over the ring of p-adic integers, such a generalization to p-compact groups of the Evens-Venkov theorem. We consider the cohomology of a space with coefficients in a module, and we compare Noetherianity over the p-adic integers, in the case when the
Increased anthropogenic pressures on coastal marine ecosystems in the last century are threatening their biodiversity and functioning. Global warming and increases in nutrient loadings are two major stressors affecting these systems. Global warming is expected to increase both atmospheric and water temperatures and increase precipitation and terrestrial runoff, further increasing organic matter an
To explore the possible influence of pre-eclampsia on cognitive outcome in children born very preterm after intrauterine growth restriction (IUGR) and abnormal umbilical artery blood flow.
OBJECTIVE: The aim of this research was to study the discomfort experienced by adolescents when answering questions in a survey about sexuality and sexual abuse and to investigate factors that may determine possible experience of discomfort. The research focused particularly on vulnerable adolescents-sexually abused and sexually inexperienced. METHOD: Adolescents in their final year of high school
Organic enrichment may deeply affect benthic nitrogen (N) cycling in macrophyte meadows, either promoting N loss or its recycling. This depends upon the plasticity of plants and of the associated microbial communities, as those surrounding the rhizosphere. Rates of denitrification, dissolved inorganic N fluxes and N uptake were measured in sediments vegetated by the submerged macrophyte Vallisneri
Polanyi’s concept of the ‘double movement’ is frequently interpreted as the opposition between the problematic and unsustainable dynamics of the market and the benign and normatively desirable reaction against this by ‘society’. This paper questions this dualistic interpretation of the double movement and undertakes a problematization of the Polanyian idea of social and environmental protection. I
Nanoconfined 2LiBH(4)-MgH2 is prepared by direct melt infiltration of bulk 2LiBH(4)-MgH2 into an inert nanoporous resorcinol-formaldehyde carbon aerogel scaffold material. Scanning electron microscopy (SEM) micrographs and energy dispersive X-ray spectroscopy (EDS) mapping reveal homogeneous dispersion of Mg (from MgH2) and B (from LiBH4) inside the carbon aerogel scaffold. Moreover, nanoconfineme
Physical exercise is a cornerstone in the management of many neurodegenerative disorders, such as Parkinson's disease, dementia, and stroke. However, much of its beneficial effects on improving motor functions and cognition as well as decreasing neurodegeneration and neuroinflammation are not yet well understood. The obvious limitations of studying the protective mechanisms behind exercise, for ex
