BACKGROUND: Inflammation and immune responses are considered to be very important in the pathogenesis of atherosclerosis. Lipid accumulation in macrophages of the arterial intima is a characteristic feature of atherosclerosis which can influence the inflammatory potential of macrophages. We studied the effects of lipid loading on the regulation of TNF expression in human monocyte-derived macrophag

Over the last two decades there has been a striking and continuous increase in the prevalence of obesity both in industrialized and developing countries. Despite this global consistency there is a variation within countries with a higher prevalence of obesity within rural areas. The overall aim was to explore the prevalence of obesity and factors that influence the development of obesity in a rura

When water is coadsorbed with oxygen at coverages above 0.25ML an intact water species is observed in high resolution X-ray photoelectron spectroscopy up to 220 K, which is significantly more stable than intact water on the clean surface. The presence of this species causes a shift in the O 1s binding energy of the pre-adsorbed oxygen, which indicates the formation of hydrogen bonds between the tw

Polyamine analogues have demonstrated anti-tumour activity in a number of solid tumour models. In the present study we compared the cytotoxicities of three polyamine analogues against four breast cancer cell lines. All cell lines are derived from tumours of women with breast cancer and, although we are sampling just a small number of tumours, they represent a spectrum of the genetic plethora of br

A terminating rotational band has been identified in Mn-51 following the Si-28(S-32,2alpha1p)Mn-51 fusion-evaporation reaction at 130 MeV beam energy. Spins and tentative positive parities of the band members are assigned based on angular distribution and correlation measurements of transitions, which connect the rotational structure with previously known yrast states. Configuration-dependent cran

The longitudinal spread zone was investigated for 30 arctic shorebird populations from 10 different wintering communities in widely different regions of both the Northern and Southern Hemispheres. Information about total breeding and wintering ranges, migratory connectivity and subspecies was compiled from literature sources. The spread of the distributions was analysed in relation to the mean dis

Endotoxin was measured in air and dust samples collected during four commercial aircraft flights. Samples were analyzed for endotoxin biological activity using the Limulus assay. 3-hydroxy fatty acids (3-OH FA) of carbon chain lengths C10:0-C18:0 were determined in dust by gas chromatography-ion trap tandem mass spectrometry. The geometric mean (geometric standard deviation) endotoxin air level wa

The pineal organ is the only differentiated photoreceptor organ present in embryos and early larvae of the Atlantic halibut (Hippoglossus hippoglossus). We investigated the molecular identity of opsins in the pineal organ, and their expression during different life stages. Using RT-PCR we identified two 681-bp gene sequences, named HPO1 and HPO4, in cDNA from adult pineal and whole embryos. The pr

Extraction of lignin by ultrafiltration of black liquor from two Swedish pulp mills has been studied. One of the mills employs batch digestion and the other continuous digestion. At both mills softwood was used as raw material. The black liquor was withdrawn before the evaporator unit. A ceramic membrane with a cut-off of 15 000 g mol(-1) was used in the experiments. The average flux during concen

Neuroblastoma is a childhood tumor derived from precursor or immature cells of the sympathetic nervous system. Neuroblastomas show a tremendous clinical heterogeneity, encompassing truly benign as well as extremely aggressive forms. In vivo as well as in vitro data have shown that the degree of sympathetic neuronal tumor cell differentiation influences patient outcome. Unraveling mechanisms govern

Popular Abstract in Swedish Psykiatriska vårdares erfarenheter av omvårdnad, grupphandledning och individuellt planerad omvårdnad på en avdelning för vård av gravt dementa personer och på en allmänpsykiatrisk avdelning. Avhandlingens övergripande syfte var att undersöka vårdarnas upplevelse av omvårdnadsarbetet samt betydelsen och effekterna av införandet av systematisk klinisk grupphandledning oThe aim of this thesis was to investigate nurses’ lived experience of daily nursing care and the impact and lived experiences of one years intervention with systematic clinical group supervision and supervised individually planned nur-sing care. This was carried out at an experimental ward (EW) (n=19) housing patients with dementia in comparison with a similar control ward (CW) (n=20) using a quas

Rapporten innehåller en detaljerad manual till PC-programmet RISK1 samt två exempel som presenteras uförligt. Programmet är det första allmänt tillgängliga för att bedöma risken eller sannolikheten för att kondens skall uppkomma i en konstruktion

Hydration of hen egg white lysozyme was studied by using the method of sorption calorimetry at 25, 40, and 50degreesC. Desorption calorimetric measurements were performed at 25 and 40degreesC. The activity of water and partial molar enthalpy of mixing of water were determined as functions of water content. Hydration of lysozyme occurs in four steps: slow penetration of water into the protein-prote