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Chronic musculoskeletal pain predicted hospitalisation due to serious medical conditions in a 10 year follow up study

BACKGROUND: The aim was to examine if self reported chronic regional pain (CRP) and chronic widespread pain (CWP) predicted inpatient care due to serious medical conditions such as cerebrovascular diseases, ischemic heart diseases, neoplasms and infectious diseases in a general population cohort over a ten year follow-up period.METHODS: A ten-year follow up of a cohort from the general adult popul

Left ventricular remodelling changes without concomitant loss of myocardial fat after long-term dietary intervention

BACKGROUND: Accumulation of myocardial triglycerides (MTG) is associated with impaired left ventricular (LV) remodelling and function in obese and diabetic subjects. The role of MTG accumulation in development of heart failure in this group of patients is unknown. Short-term studies suggest that diets that lead to weight loss could mobilize MTG, with a favourable effect on cardiac remodelling. In

Destination employment? : Contradictions and ambiguities in Swedish labour market policy for newly arrived migrants

Sweden’s “establishment reform” was introduced in 2010 with the ambition to increase the labour market participation of newly arrived migrants. It was in line with other labour market policies of the centre-right Alliance government, elected in 2006, which aimed to increase work incentives particularly for groups seen as “vulnerable” in, or excluded from, the labour market.By considering the histo

The use and diagnostic yield of radiology in subjects with longstanding musculoskeletal pain : an eight year follow up

BACKGROUND: Longstanding musculoskeletal pain is common in the general population and associated with frequent use of health care. Plain radiography is a common diagnostic approach in these patients despite knowledge that the use in the investigation of musculoskeletal pain is associated with low diagnostic yield, substantial costs and high radiation exposure. The aim of this study was to assess t

International Trade and Energy Intensity during European Industrialization, 1870-1935

Previous research suggests that there is an inverted U-shape curve for energy intensity in the long-run for Western Europewith a peak in the early 20th century. This paper tests the hypothesis that the increase of German and British energy intensity was an effect from the concentration of heavy industrial production to these countries, although the consumption of a significant share of these goods

Valentinianernas evangelium : Gnosticismen och den antika kristna idévärlden i ljuset av texterna från Nag Hammadi

Valentinus av Alexandria var en teolog och predikant vars verksamhet under det andra århundradet fick stort genomslag. Valentinianernas evangelium – den världsbild och teologi som kan knytas till Valentinus och hans efterföljare – var intimt förknippat med fenomenet gnosticism. Men vad är egentligen gnosticism och hur hänger den ihop med kristendom? Den här boken är en introduktion till antik gnos

Maximizing level of confidence for non-equidistant Checkpointing

Employing fault tolerance often introduces a time overhead, which may cause a deadline violation in real-time systems (RTS). Therefore, for RTS it is important to optimize the fault tolerance techniques such that the probability to meet the deadlines, i.e. The Level of Confidence (LoC), is maximized. Previous studies have focused on evaluating the LoC for equidistant checkpointing. However, no stu

The Russian daily press, 1978-2003 : political argumentation and the problematic public sphere

The language of newspapers in the public sphere has a crucial impact on how the public perceives and participates in society. It can serve to encourage or counteract active and informed citizens; in fact, it is a crucial element in democratisation processes. The purposes of the present study are to elucidate what means of persuasion are used to support theses on politics in newspaper discours

Rheumatoid arthritis as underlying cause of death in 31 countries, 1987-2011: Trend analysis of WHO mortality database

Objective To examine trends in rheumatoid arthritis (RA) as an underlying cause of death (UCD) in 31 countries across the globe during 1987-2011. Methods Data on mortality and population were collected from the World Health Organization mortality database and the United Nations. Age-standardized mortality rates (ASMR) were calculated by means of direct standardization. We applied joinpoint regress

Galactose-amidine derivatives as selective antagonists of galectin-9

The family of galectin proteins involved in adhesion, growth regulation, immunity, and inflammatory events are important targets for development of small molecule antagonists. Here, N-sulfonyl amidine galactopyranoside derivatives obtained via a multicomponent reaction between galactose alkyne derivatives, sulfonyl azides, and amines were evaluated as antagonists of galectin-1,-2,-3,-4N (N-termina

Lock-in of mature innovation systems : The transformation toward clean concrete in the Netherlands

Energy-intensive processing industries like the concrete industry form the base of the economy and account for a large part of global greenhouse gas emissions. Sectoral transformation to cleaner basic materials is therefore crucial, and institutional pressure to do so is increasing. However, socio-technical studies have not sufficiently addressed these sectors. This paper therefore sets out to ana

English : One Tongue, Many Voices

'If you read only one book on the English language-read this one. English - One Tongue, Many Voices covers all aspects of the English language: its global spread, international and local varieties, history from obscurity to primacy, usage and uses, standards and creoles, style and change in progress, politics and controversy. The scope of the book is vast, its depth impressive, and its balance adm

Molecular characterization of protein kinase C delta (PKCδ)-Smac interactions

Background: Protein kinase C o (PKCo) is known to be an important regulator of apoptosis, having mainly pro-but also anti-Apoptotic effects depending on context. In a previous study, we found that PKCo interacts with the pro-Apoptotic protein Smac. Smac facilitates apoptosis by suppressing inhibitor of apoptosis proteins (IAPs). We previously established that the PKCo-Smac complex dissociates duri

Intensity interferometry : Optical imaging with kilometer baselines

Optical imaging with microarcsecond resolution will reveal details across and outside stellar surfaces but requires kilometer-scale interferometers, challenging to realize either on the ground or in space. Intensity interferometry, electronically connecting independent telescopes, has a noise budget that relates to the electronic time resolution, circumventing issues of atmospheric turbulence. Ext