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Recombinant adeno-associated viral vectors (rAAVs) have become an industry-standard technology in the field of gene therapy, but there are still challenges to be addressed in their biomanufacturing. One of the biggest challenges is the removal of capsid species other than that which contains the gene of interest. In this work, we develop a mechanistic model for the removal of empty capsids—those t

Here we present geomorphological evidence of a previously unrecognised ∼50 km long, ice-marginal moraine complex in southwestern Skåne, southernmost Sweden, which we name the “Lund Moraine”. This lobate moraine marks a sharp boundary between heavily streamlined and gently undulating landscapes, and closely outlines the extent of the “Lund till/diamicton”. We interpret that the moraine was formed b

Pd possesses attractive catalytic properties and nano-structuring is an obvious way to enhance catalytic activity. Alloying Pd with Pb has been shown to enhance the catalytic effect of alcohol oxidation. Further optimization of the catalytic effect can be accomplished by controlling the particle size and key to this is understanding the formation mechanism. By monitoring solvothermal syntheses usi

Next generation of high-NA extreme ultraviolet (EUV) photolithography introduces higher power levels and faster reticle accelerations, enabling breakthrough in scanner efficiency. This results in higher temperatures and mechanical stresses on the EUV pellicles. Here we demonstrate scalable carbon nanotube (CNT) membrane mass production from a floating catalyst chemical vapor deposition (FC-CVD) re

Metal halide perovskites (MHPs) have become a widely studied class of semiconductors for various optoelectronic devices. The possibility to tune their bandgap (Eg) over a broad spectral range from 1.2 eV to 3 eV by compositional engineering makes them particularly attractive for light emitting devices and multi-junction solar cells. In this metadata study, data from Peer-reviewed publications avai

Optimizing processes and materials for the valorization of CO2 to hydrogen carriers or platform chemicals is a key step for mitigating global warming and for the sustainable use of renewables. We report here on the hydrogenation of CO2 in water on ZnO-supported CuAu nanoalloys, based on ≤7 mol % Au. CuxAuy/ZnO catalysts were characterized using 197Au Mössbauer, in situ X-ray absorption (Au LIII- a

Sociology of philosophy is the name of a theory-based, empirical sociological subdivision, whose basic approach is praxeological: doing philosophy involves a variety of socially situated practices that in some cases result in philosophical arguments and doctrines fixed in text. Constellation research is an approach developed by the German philosopher Dieter Henrich (1927–2022) for investigations i

Background: Antibody-mediated complement fixation has previously been associated with protection against malaria in naturally acquired immunity. However, the process of early-life development of complement-fixing antibodies in infants, both in comparison to their respective mothers and to other immune parameters, remains less clear. Results: We measured complement-fixing antibodies in newborns and

Background: The aim was to investigate to what extent the quantification of myocardial blood flow (MBF) from dynamic 13N-NH3 positron emission tomography (PET) images is affected by time frame schemes, time-of-flight (ToF), reconstruction algorithms, blood pool volume of interest (VOI) locations and compartment models in patients with suspected chronic coronary syndrome. Methods: A standard MBF va

Robots and autonomous systems are being developed at an ever-increasing rate. Autonomous systems are already prolific in many households around the world, and their adoption is only expected to increase over the coming decades. Even so, many of the systems that are deployed today are still prone to small operational errors such as struggling to navigate complex environments. While the argument ove

The generalized asymmetric Laplace (GAL) distributions, also known as the variance/mean-gamma models, constitute a popular flexible class of distributions that can account for peakedness, skewness, and heavier-than-normal tails, often observed in financial or other empirical data. We consider extensions of the GAL distribution to the matrix variate case, which arise as covariance mixtures of matri

This chapter is an attempt to provide an interdisciplinary approach and appraisal. Methodologically, the chapter combines law with several disciplines in cultural studies, namely, history, ethics, and philosophy. The overarching objective is to provide a succinct overview of the development of China's Belt and Road Initiative (BRI) while, at the same time, homing in on some of the main themes and

Background: Dietary carbohydrates are a major source of energy in the Nordic and Baltic countries. The health effects of different types of carbohydrates vary and there is a need to update the evidence regarding specific carbohydrates and their effects on health-related outcomes. Objective: The aim of this scoping review was to describe the evidence for the role of total carbohydrates (fiber exclu

The purpose of this study was to describe experiences of pain among students at upper secondary schools (adolescents aged 16–19 years) in Sweden. Focus group (n = 9) interviews with 41 adolescents were conducted in southern Sweden in 2021. The interviews were analyzed by qualitative content analysis, which identified four categories encompassing the theme how pain expressed itself: (1) a warning b

This paper explores how the Helsinki process altered practices within the Swedish Pentecostal community. In order to understand this process of change, we need to take two fundamental, and slightly contradictory, traits related to the East-West conflict found among this religious grouping into account. First, post-WWII Swedish Pentecostals were in general vehemently opposed to Communism and to the

In this paper, we investigate the effects of different augmentation strategies in self-supervised representation learning from electrocardiograms. Our study examines the impact of random resized crop and time out on downstream performance. We also consider the importance of the signal length. Furthermore, instead of using two augmented copies of the sample as a positive pair, we suggest augmenting

We introduce a model description of a diatomic molecule in an optical cavity, with pump and fluorescent fields, and electron and nuclear motion are treated on equal footing and exactly. The model accounts for several optical response temporal scenarios: A Mollow spectrum hindered by electron correlations, a competition of harmonic generation and molecular dissociation, a dependence of fluorescence

Background: Primary hyperparathyroidism (PHPT) is a common endocrine disorder. Definitive treatment is surgical. Preoperative localization of diseased glands increases the chance of successful treatment. The aim of this study is to investigate the diagnostic performance of 18F-fluoromethylcholine-positron emission tomography-computed tomography (18F-FCh-PET-CT) in preoperative localization of dise

Scientific uncertainty is clearly a prominent hurdle in public health policy and the policy choices made to tackle this uncertainty are largely left to the Member States. Indeed, the Court of Justice of the EU has long since held that the health and the life of humans rank first among the interests that Member States can legitimately pursue - even if they restrict the market freedoms in doing so -