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Heart and lung transplantation remain the primary treatments for end-stage organ failure; yet organ shortages and ischemia-reperfusion injury (IRI) limit their success. Extended criteria donors (ECDs) have expanded the donor pool; however, prolonged cold ischemia times increase the risk of primary graft dysfunction (PGD). Static cold storage (SCS), the standard organ preservation method, is subopt
Embodiment has slowly been integrated as a category of analysis in (critical) military studies. In this article, we argue that embodiment–and related concepts such as body, affects and emotions–has become prevalent concerns over the 10-year consolidation of the intellectual project of the journal CMS. We propose an inquiry organized around three axes: situating current debates in the broader field
Cyanobacteria are bioactive compounds that produce toxins known as harmful algal blooms, posing serious threats to humans and marine life. Consequently, developing a robust monitoring framework to track and forecast the growth of such blooms is critical. The present work aims to understand the key environmental drivers influencing cyanobacterial bloom dynamics along the Southeast coast of India us
This letter addresses loss of packets in a wireless fronthaul link being interpreted as channel errors for the service link. This may occur if, for instance, User Equipment (UE) is served by a radio unit in an Uncrewed Aerial Vehicle (UAV) via a wireless fronthaul link to a baseband unit (BU) on the ground. The fronthaul packet loss leads to a mismatch between the real and estimated channel state,
This study investigates properties of mastics produced with 70/100 neat bitumen, three mineral fillers (granite, quartz-granite, and diorite), and a lime-based active filler at filler-to-bitumen (F/B) ratios of 40%, 50%, and 60%. The physical, geometrical, and mineralogical properties of the fillers were assessed. Their influence on mastics' behaviour was evaluated using conventional penetration a
This study aims to explore the mechanism through which Yishen Jiangtang Decoction (YSJTD) regulates endoplasmic reticulum stress (ERS)-mediated NOD-like receptor thermal protein domain associated protein 3 (NLRP3) inflammasome to improve diabetic nephropathy (DN) in db/ db mice. Thirty db/ db mice were randomly divided into the model group, YSJTD group, ERS inhibitor 4-phenylbutyric acid (4-PBA) g
Background: Pancreatic cancer continues to retain the highest mortality rate among all major organ cancers. New strategies for early detection are being proposed to increase long-term survival. A plethora of molecular markers are discovered yearly, but so far none have demonstrated screening utility. Summary: Promising discovery technologies include affinity-based proteomics and ddPCR. In the vali
We present a genome assembly from an individual female Podarcis tiliguerta (Tyrrhenian Wall Lizard; Chordata; Lepidosauria; Squamata; Lacertidae). The assembly contains two haplotypes with total lengths of 1 462.31 megabases and 1 394.94 megabases. Most of haplotype 1 (99.26%) is scaffolded into 20 chromosomal pseudomolecules, including the W and Z sex chromosomes. Most of haplotype 2 (99.2%) is s
Neuromuscular disorders (NMDs) are disorders of the motor unit (motor neuron diseases, diseases of the peripheral nerves, neuromuscular junction diseases, and diseases affecting the muscle fibers). A common denominator of these diseases is muscle atrophy and progressive weakness. Quantitative assessments of muscle function are therefore essential to follow disease progression, to understand the as
This article examines the production of climate-related loss, specifically loss of access to land, among Indigenous and ethnic minority farming communities in northeastern Cambodia. We analyse how rapid socio-environmental and political-economic changes are eroding smallholder farmers' capacities to cope with climate impacts and can lead to what we call climate-related loss. We show how climate ch
The Lepidoptera, butterflies and moths, display an astonishing diversity of spatial orientation strategies essential for survival, reproduction, and ecological success. These spatial orientation strategies range from basic taxes to light, wind, gravity, and chemical cues, to more advanced strategies such as straight-line dispersal, multigenerational migration across continents, and complex trap-li
Droplets are sophisticated micro-compartments crucial for lab-on-a-chip and bio-medical applications. There have been significant efforts towards generating monodisperse droplets as the uniformity of droplets affects performance. Recently, we introduced a new method to continuously reform existing emulsions improving monodispersity in an ultrasound-actuated microcavity via a trap-coalesce-split me
Gamification is an increasingly popular topic in manufacturing research, since it can enhance workers’ engagement and reduce their errors. Manufacturing is a traditionally male-dominated industry, however females face greater risks compared to their male counterparts, and the number of highly skilled female workers is increasing. This contribution presents the results from the pre-test of a gamifi
Background: Systemic lupus erythematosus (SLE) is an autoimmune disease with a heterogenous clinical picture. This study aimed to link genetic SLE predisposition with relevant clinical manifestations. Method: Datasets best corresponding to the 11 American College of Rheumatology 1982 (ACR-82) classification criteria for SLE in a large, public database (FinnGen consortium, >218,000 individuals) wer
Background: Creatinine-based estimated glomerular filtration rate (eGFR) equations are widely used in clinical practice but exhibit inherent limitations. On the other side, measuring GFR is time consuming and not available in routine clinical practice. We developed and validated machine learning models to assess the trustworthiness (i.e. the ability of equations to estimate measured GFR (mGFR) wit
Background: Minimising time from injury to hospital admission is considered a key factor in trauma. Trauma care is often centralised to hospitals, which, because of their urban location, make treatment more accessible to patients in densely populated areas. If prehospital time increases with declining population density, an effect on mortality could hence be present. The primary aim of this study
Background: Individuals with diabetes (DM) are often treated with statins, which have a rare side effect: peripheral neuropathy. We aimed to study whether statin treatment affects the risk of carpal tunnel syndrome (CTS) and ulnar nerve entrapment (UNE) in type 2 DM (T2DM). Methods: We combined multiple national registers in Sweden to identify individuals diagnosed with CTS or UNE in specialized c
Synthetic Data Generation (SDG) based on Artificial Intelligence (AI) can transform the way clinical medicine is delivered by overcoming privacy barriers that currently render clinical data sharing difficult. This is the key to accelerating the development of digital tools contributing to enhanced patient safety. Such tools include robust data-driven clinical decision support systems, and example-
Glycophospholipids combine the structural versatility of phospholipids and carbohydrates, but their potential as excipients and performance in other related applications remains largely unexplored due to their low natural abundance. We have synthesized four novel phosphatidyl saccharide conjugates with different carbohydrate head groups; glucose, galactose, fructose and xylose by using a Phospholi
This response to Alister McGrath’s The Nature of Christian Doctrine examines the interplay between Scripture, the Rule of Faith, and evolving Christian doctrine and tradition. Focusing on McGrath’s critique of Lindbeck’s presentation of doctrinal modalities, the article explores how doctrinal formation involves primarily synchronic (canonical), but also diachronic (historical), approaches to scrip
