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Contrast-enhanced MRI and synovial fluid molecule markers, new means to monitor joint diseases.

Emerging knowledge of cartilage metabolism and structure has stimulated efforts to develop new cartilage-monitoring techniques in health and disease. This article gives an overview of cartilage matrix structure, cartilage metabolism, and significant exogenous factors to show how such knowledge can guide the development of new means to monitor cartilage. Delayed contrast enhanced MRI of cartilage

Histamine and chromogranin A-derived peptides in rat stomach ECL cells

Popular Abstract in Swedish ECL-cellen är en hormonproducerande cell i magslemhinnan. Den utsöndrar histamin vilken i sin tur reglerar magsäckens saltsyrautsöndring. I avhandlingen utvecklades en metod som möjliggör mätningar av histaminutsöndringen från ECL-celler i vakna råttor. Metoden bygger på att ett semipermeabelt membran opereras in i magslemhinnan varpå histamin och andra substanser som fThe ECL cells constitute the predominant endocrine cell population of the stomach. They secrete histamine which is a major stimulator of acid secretion. Chormogranin A (CgA)-derived peptides, such as pancreastatin, are co-secreted with histamine. In this thesis it was demonstrated that pancreastatin may serve as a reliable marker for ECL cell secretory activity in the rat. The function of pancreas