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Inflammatory bowel disease (IBD) is a chronic inflammatory condition affecting the gastrointestinal tract, with a remitting and relapsing course. There are two main forms of IBD: Crohn’s disease (CD) and ulcerative colitis (UC). The etiology of IBD is not fully understood, however both CD and UC thought to be closely associated with dysregulated innate and adaptive immune responses. The aim of thi
Introduction: Information on follow-up practices after stroke in clinical routine are sparse. We studied the probability of doctor’s follow-up within 90, 120, 180, and 365 days after hospital discharge, and how patient characteristics were associated with the probability of follow-up, in a large unselected stroke cohort. Patients and methods: Data on patients living in southern Sweden, hospitalize
Mitochondrial dysfunction may result in a variety of diseases. The objectives here were to examine possible differences in mtDNA copy number between healthy controls and patients with depression, anxiety or stress- and adjustment disorders; the association between mtDNA copy number and disease severity at baseline; and the association between mtDNA copy number and response after an 8-week treatmen
In Swedish today, du (‘you’) is sometimes used with generic reference. This use of generic du is often claimed to be a new invention, triggered by English influence in the late 20th century. However, in this article an analysis of occurrences of du from the period 1225–2013 is presented that demonstrates that generic du was used even as early as the Old Swedish period (1225–1526), i.e. long beforeIn Swedish today, du (‘you’) is sometimes used with generic reference. This use of generic du is often claimed to be a new invention, triggered by English influence in the late 20th century. However, in this article an analysis of occurrences of du from the period 1225–2013 is presented that demonstrates that generic du was used even as early as the Old Swedish period (1225–1526), i.e. long befor
Objectives: To investigate the association between cognitive decline and cortical atrophy in individuals with mild cognitive impairment (MCI) and chronic subsyndromal symptoms of depression (SSD) over a 4-year period. Design: Prospective cohort study. Setting: Multicenter, clinic-based. Participants: Within the Alzheimer's Disease Neuroimaging Initiative repository, the Neuropsychiatric Inventory
Objectives: To systematically review measurement properties of visual assessment and rating of Postural Orientation Errors (POEs) in participants with or without lower extremity musculoskeletal disorders. Methods: A systematic review according to the PRISMA guidelines was conducted. The search was performed in Medline (Pubmed), CINAHL and EMBASE (OVID) databases until August 2016. Studies reportin
Precision medicine aims to predict a patient's disease risk and best therapeutic options by using that individual's genetic sequencing data. The Critical Assessment of Genome Interpretation (CAGI) is a community experiment consisting of genotype-phenotype prediction challenges; participants build models, undergo assessment, and share key findings. For CAGI 4, three challenges involved using exome-
Den föreslagna omregleringen av den svenska spelmarknaden väcker flera EU-rättsliga frågor som berörs i denna analys. En viktig fråga är om det är problematiskt att marknaden delas upp i olika delar där endast en del är konkurrensutsatt. En annan är om den föreslagna svenska spelpolitiken är trovärdig i ett EU-rättsligt perspektiv, dvs. systematisk och sammanhängande. Spellicensutredningen föreslå
Summer music festivals that involve a few days of camping have often been linked to sustainability agendas. Yet relevant studies have so far overlooked how these events can themselves serve as experiments in less resource consumptive living. Building on a wider interest in the cultural evolution of cleanliness norms, this paper explores how attendees come to use water in personal washing at two UK
A large number of mathematical models have been proposed to describe the measured signal in diffusion-weighted (DW) magnetic resonance imaging (MRI). However, model comparison to date focuses only on specific subclasses, e.g. compartment models or signal models, and little or no information is available in the literature on how performance varies among the different types of models. To address thi
Objectives: To explore associations between carer burden and characteristics of (1) the informal carer, (2) the person with dementia, and (3) the care support network in 8 European countries. Design: Cross-sectional study. Setting: People with dementia judged at risk of admission to long-term care (LTC) facilities in 8 European countries (Estonia, Finland, France, Germany, Netherlands, Spain, Swed
This thesis studies the complicated relationship between postwar social governance and neoliberalism. It looks at urban planning in particular because this is a key field of postwar social regulation as well as a strategic site of neoliberal reforms. The thesis examines urban planning paperwork from the Swedish city Malmö dating from the mid-1980s until 2015 with a particular focus on Folkets park
Phenotypic variance heterogeneity across genotypes at a single nucleotide polymorphism (SNP) may reflect underlying gene-environment (G×E) or gene-gene interactions. We modeled variance heterogeneity for blood lipids and BMI in up to 44,211 participants and investigated relationships between variance effects (Pv), G×E interaction effects (with smoking and physical activity), and marginal genetic e
There is a strong industrial drive to use cloud computing technologies and concepts for providing timing sensitive services in the networking domain since it would provide the means to share the physical resources among multiple users and thus increase the elasticity and reduce the costs. In this work, we develop a mathematical model for user-stateless virtual network functions forming a forwardin
