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Pancreatic steatosis is a risk factor for pancreatic cysts among patients with diabetes

Objectives: To investigate whether pancreatic steatosis is associated with the presence of pancreatic cysts among individuals with diabetes. Material and Methods: 158 individuals [mean age 66 ± 10 years, 81 (51%) female] with diabetes [135 (85%) had type 2 diabetes] participated in the study involving Magnetic Resonance Imaging (MRI), blood tests and anthropometric measurements. Pancreatic steatos

Seconds after aerosolisation : the impact of relative humidity on airborne influenza virus

Influenza A virus (IAV) is a major respiratory pathogen, causing around 650,000 deaths annually. Asignificant transmission pathway for IAV is via expelled respiratory aerosol. For successfultransmission via the aerosol route, IAV must remain infectious following transport from an infectedhost to a susceptible individual. Many environmental factors may affect IAV infectivity, includingambient relat

Environmental enrichment modulates chronic poststroke inflammation and links white matter TREM2-positive microglia in recovery in mice

Background: Environmental enrichment (EE) has been widely reported to improve functional recovery after stroke, yet its effects on chronic inflammation and white matter pathology remain less well defined. The aim of this study was to investigate whether poststroke EE modulates chronic neuroinflammation and white matter pathology and how these changes relate to functional recovery. Methods: Here, w

Better reporting is better science : Community-defined minimal reporting requirements for light microscopy

Incomplete reporting of microscopy methods undermines transparency, reproducibility, and data reuse. Despite recent initiatives, comprehensive, broadly endorsed, and accessible reporting guidelines are still lacking. Here, we present a bare minimal microscopy reporting requirements checklist that integrates human- and machine-readable input to provide clear, actionable guidance for researchers, re

The cloud has wires : Toward circular governance of smart grids

Smart grids are widely promoted as efficient, low-carbon solutions for energy transitions, yet their governance often treats digital infrastructure as immaterial and uniformly beneficial. This obscures the material, temporal, and justice dimensions that shape real-world outcomes. We introduce Circular Grid Governance (CGG), a framework that integrates circular-economy principles, lifecycle thinkin

Protocol for efficient CRISPRi-mediated silencing of retrotransposons in human pluripotent stem cells

Here, we present a workflow for transcriptional silencing of transposable elements (TEs) in human induced pluripotent stem cells (hiPSCs). We describe steps for designing guide RNAs (gRNAs) to target TE families or unique TE loci. We also detail procedures for validating the efficiency and specificity of large-scale CRISPRi-based silencing using a multiome approach combining bulk RNA sequencing, C

Towards a Standard Protocol for Fecal Microbiota Transplantation in Irritable Bowel Syndrome

Randomized controlled trials (RCTs) of fecal microbiota transplantation (FMT) in patients with irritable bowel syndrome (IBS) have produced outcomes varying from no effect at all to high efficacy and durable effects over time. This review analyzed differences in the protocols used in FMT RCTs for IBS in the recently published literature with the aim of identifying the factors responsible for the s

Making digital welfare work: conceptualizing digital compensatory work by frontline professionals

Digital technologies in welfare organizations frequently generate gaps, ambiguities, and misalignments that require professional intervention. Yet prior research has tended to portray frontline workers mainly as resistant or adaptive actors, leaving under-examined their active contributions to sustaining broader digital infrastructures. This article introduces the concept of digital compensatory wDigital technologies in welfare organizations frequently generate gaps, ambiguities, andmisalignments that require professional intervention. Yet prior research has tended to portrayfrontline workers mainly as resistant or adaptive actors, leaving under-examined their activecontributions to sustaining broader digital infrastructures. This article introduces the concept ofdigital compensatory work

Management of Idiopathic Acute Pancreatitis in Europe : An International Pancreas2000 Survey

BACKGROUND: Identifying the underlying cause of acute pancreatitis is fundamental for prevention of recurrence. However, no standardised algorithm for determining its aetiology exists.AIMS: This survey study aimed to investigate the international variations in diagnosis, workup protocols and follow-up of acute pancreatitis.METHODS: A 37-item international questionnaire was developed by a multidisc

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Accessibility to art and cultural activities is a topic with increasing attention. Most municipalities in the Scandinavian countries have kulturskoler (extra curricular schools of music and performing arts) that offer training and experiences in – and through – art and culture subjects for children and young people. But the users of these institutions are not representative for the society around

Do breakout haplotypes drive parasitemia spikes in avian malaria?

During an infection, the genetic composition of the pathogen population in the host might range from clonal to genetically diverse, depending on the genetic variation of the inoculum, mutation events, genetic drift, and host selection during the course of the infection. Variation in the genetic diversity of avian malaria parasites, both within and between individual hosts, is not well documented.

Component-Specific Functions of Cu, Zn, and Zr in Inverse ZnZrOx/Cu Catalysts for CO2Hydrogenation to Methanol

Cu-based ternary catalysts often outperform their binary counterparts in the hydrogenation of CO2 to methanol. Unraveling the underlying synergistic effects among multiple components remains challenging and requires comprehensive operando characterization. In this study, we present a detailed investigation into the synergistic Cu−Zn−Zr interactions in inverse ZnZrOx/Cu catalysts, which show strong

First confirmed finds of baleen whale from Iron Age Scania, Sweden, and their archaeological implications

This paper presents hitherto unknown finds of baleen whale from Iron Age Scania. Through the peptide-based technique Zooarchaeology by Mass Spectrometry (ZooMS), we provide the first identifications of remains of humpback whale (Megaptera novaeaenglia) and fin whale (Balaenoptera physalus) in Scania and we present the first identification of North Atlantic right whale (Eubalaena glacialis) or bowh

The representation of climate impacts in the FRIDAv2.1 Integrated Assessment Model

Feedbacks from the climate to other components of the coupled human-Earth system are expected to strongly influence the co-evolution of human society and its environment. Representing these feedback loops between climate and society, via the Earth system's response to human activities and the subsequent effect back onto social systems, is essential in order to fully explore the dynamics of the cou

Primary squamous cell carcinoma of the external auditory canal–a nationwide study

Background: National studies on primary malignant tumours arising from the external auditory canal (EAC) are rare. Objectives: To investigate the incidence and outcomes of squamous cell carcinoma of the external auditory canal (SCC-EAC) in Sweden. Materials and methods: The retrospective study included patients diagnosed with SCC-EAC in Sweden from 2007 to 2017. Results: Forty-six patients with SC