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Computer-assisted calculation of myocardial infarct size shortens the evaluation time of contrast-enhanced cardiac MRI

Background: Delayed enhancement magnetic resonance imaging depicts scar in the left ventricle which can be quantitatively measured. Manual segmentation and scar determination is time consuming. The purpose of this study was to evaluate a software for infarct quantification, to compare with manual scar determination, and to measure the time saved. Methods: Delayed enhancement magnetic resonance ima

Health-economic consequences of diabetic foot lesions.

Abstract in UndeterminedDiabetic foot complications result in huge costs for both society and the individual patients. Few reports on the health-economic consequences of diabetic foot infections have been published. In studies considering a wide societal perspective, costs of antibiotics were relatively low, whereas total costs for topical treatment were high relative to the total costs of foot in

Citral a fragrance allergen and irritant

Citral is a well known contact allergen and a contact irritant. Routine patch testing in the past may have been restricted because of possible irritant (IR) patch test responses. 586 consecutive patients, with hand eczema, were patch tested with a selection of fragrances including citral 2% petrolatum and the European standard series. 28 of the patients showed a positive patch test reaction (+ to

Biotite and muscovite 40Ar/39Ar geochronological constraints on the post-Svecofennian tectonothermal evolution, Forsmark site, central Sweden

In order to characterize the post-Svecofennian tectonothermal evolution of the Fennoscandian Shield, 40Ar-39Ar biotite and some 40Ar-39Ar muscovite geochronological data are reported from a total of 30 surface outcrop and 1000 m long borehole samples at Forsmark, central Sweden. The thirteen surface samples were collected across three branches of a major WNW to NW trending system of deformation zo

Dispersed lipid liquid crystalline phases stabilized by a hydrophobically modified cellulose

Aqueous dispersions of monoolein (MO) with a commercial hydrophobically modified ethyl hydroxyethyl cellulose ether (HMEHEC) have been investigated with respect to the morphologies of the liquid crystalline nanoparticles. Only very low proportions of HMEHEC are accepted in the cubic and lamellar phases of the monoolein-water system. Due to the broad variation of composition and size of the commerc

Testing for panel cointegration with multiple structural breaks

This paper proposes a Lagrange multiplier (LM) test for the null hypothesis of cointegration that allows for the possibility of multiple structural breaks in both the level and trend of a cointegrated panel regression. The test is general enough to allow for endogenous regressors, serial correlation and an unknown number of breaks that may be located at different dates for different individuals. W

Metal toxicity affects fungal and bacterial activities in soil differently

Although the toxic effect of heavy metals on soil microorganism activity is well known, little is known about the effects on different organism groups. The influence of heavy metal addition on total, bacterial, and fungal activities was therefore studied for up to 60 days in a laboratory experiment using forest soil contaminated with different concentrations of Zn or Cu. The effects of the metals

Risk of plasma cell and lymphoproliferative disorders among 14 621 first-degree relatives of 4458 patients with monoclonal gammopathy of undetermined significance in Sweden

Familial clustering of the precursor condition, monoclonal gammopathy of undetermined significance (MGUS) has been observed in case reports and in smaller studies. Using population-based data from Sweden, we identified 4458 MGUS patients, 17 505 population-based controls, and first-degree relatives of patients (n = 14 621) and controls (n = 58 387) with the aim to assess risk of MGUS and lymphopro

Genetic aberrations in hypodiploid breast cancer: frequent loss of chromosome 4 and amplification of cyclin D1 oncogene

The evolution of somatic genetic aberrations in breast cancer has remained poorly understood. The most common chromosomal abnormality is hyperdiploidy, which is thought to arise via a transient hypodiploid state. However, hypodiploidy persists in 1 to 2% of breast tumors, which are characterized by a poor prognosis. We studied the genetic aberrations in 15 flow cytometrically hypodiploid breast ca

Four-wave mixing with non-resonant pump and resonant probe for OH detection in flames

A new type of two-color four-wave mixing spectroscopy is theoretically and experimentally demonstrated. By employing a non-resonant pumping and resonant probing scheme, OH radicals are detected in a laminar, atmospheric pressure methane/air flame as a proof-of-principle experiment. Two 532 nm laser beams from a multi-mode Nd:YAG laser are utilized to create an electrostrictive grating in the flame

Spatio-temporal statistical modelling of significant wave height

In this paper. we construct a homogeneous spatio-temporal model to describe the variability of significant wave height over small regions of the sea and over short periods of time. Then. the model is extended to a non-homogeneous one that is valid over larger areas of the sea and for time periods of up to 10 h. To validate the proposed model. we reconstruct the significant wave height surface unde

Visualisation of ectomycorrhizal rhizomorph structure using laser scanning confocal microscopy

A method for the observation of the three-dimensional structure of intact ectomycorrhizal rhizomorphs is described. The method is based on a combination of clearing the material with KOH followed by staining with congo red and subsequent imaging under a laser scanning confocal microscope (LSCM). The images obtained are of a much higher three-dimensional resolution than those obtained previously by

A long-term follow-up study of adolescents with conduct disorder: Can outcome be predicted from self-concept and intelligence?

Background: This study examines Swedish young adults (age 21) with a history of conduct disorder (CD) in adolescence. Research has established CD as a condition for a range of adverse outcomes. Intelligence, aggression, parent-child conflict, parent-child relation and peer-rejection are known factors influencing the outcome. Aim: The aim of this longitudinal study is to find how self-confidence an

S-100beta stimulates neurite outgrowth in the rat sciatic nerve grafted with acellular muscle transplants

S-100beta promotes neurite extension in vitro and motoneuron survival in the chicken embryo. We demonstrate here that local administration of S-100beta stimulates the sciatic nerve regeneration into acellular muscle grafts. Normally there is a 8-10 day delay in the regeneration of axons into such grafts. Local administration of S-100beta (0.5-1.0 microg/h) significantly stimulated regeneration int

Therapeutic choices for patients with hemophilia and high-titer inhibitors

Effective treatment of bleeding episodes in hemophilia with high titer inhibitors (HTI) remains a challenge, despite the fact that the therapeutic armamentarium has expanded considerably over the past few years. Treatment safety has improved with the availability of porcine factor VIII (FVIII) and bypassing products such as recombinant factor VIIa (rFVIIa), and plasma-derived activated Prothrombin