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Undantag från kravet på etikprövning av humanistisk och samhällsvetenskaplig forskning. En internationell utblick

The Swedish ethical review system has recently come under heavy criticism - criticism that has largely centered on the system’s negative impact on research in the humanities and social sciences. Among other things, it has been claimed that the requirement for ethical review is unnecessarily comprehensive. One way of exploring the reasonableness of the Swedish system is to compare it with the rules

A data-driven approach for understanding invalid bug reports: An industrial case study

Context:Bug reports created during software development and maintenance do not always describe deviations from a system’s valid behavior. Such invalid bug reports may consume significant resources and adversely affect the prioritization and resolution of valid bug reports. There is a need to identify preventive actions to reduce the inflow of invalid bug reports. Existing research has shown that m

Slutet på den nordiska koncernbidragsmodellen? – En analys av mål E-3/21 PRA i EFTA-domstolen

Den 1 juni 2022 meddelade EFTA-domstolen sitt avgörande i målet PRA. EFTA-domstolen fann att möjligheten för norska bolag att genom koncernbidrag öka EBITDA och därmed storleken på tillåtna ränteavdrag var oförenligt med etableringsfriheten. Enligt domstolen kunde denna inskränkning av etableringsfriheten enbart rättfärdigas om syftet med lagstiftning vore att motverka rättsmissbruk. Med tanke på

Den esoteriske Fröding

Frödings kunskaper om Helena Blavastkys Isis Univeiled och teosofin blev betydelsefull för hans diktning och tänkande om varat och själens tillvaro efter döden, om skuld och straff och försoning. Här analyseras flera av hans dikter i ljuset av teosofins läror.

Cotinine concentrations in maternal serum and amniotic fluid during pregnancy and risk of testicular germ cell cancer in the offspring : A prospective nested case-control study

Maternal smoking in pregnancy may increase the risk of testicular germ cell cancer (TGCC) in offspring, but current evidence remains inconclusive. We performed a nested case-control study using cotinine measurements in maternal serum and amniotic fluid as a biomarker for tobacco exposure during pregnancy. A total of 654 males with maternal serum (n = 359, ncases/controls = 71/288) and/or amniotic

Basis transform in linear switched system models from input–output data

This article addresses the problem of basis correction in the context of linear switched-system (LSS) identification from input–output data. It is often the case that identification algorithms for the LSSs from input–output data operate locally. The local submodel estimates, identified individually by subspace algorithms from the input-output data, reside in different-state bases, which mandates p

A probabilistic assessment of surface water-groundwater exchange flux at a PCE contaminated site using groundwater modelling

Polluted groundwater discharge at a chlorinated solvent contaminated site in Hagfors, Sweden, is affecting a nearby stream flowing through a sparsely populated area. Because of difficulties related to source zone remediation, decision makers recently changed the short-term site management objective to mitigating discharge of polluted groundwater to the stream. To help formulating targeted remediat

Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer's disease pathogenesis

The hippocampus is a primary region affected in Alzheimer's disease (AD). Because AD postmortem brain tissue is not available prior to symptomatic stage, we lack understanding of early cellular pathogenic mechanisms. To address this issue, we examined the cellular origin and progression of AD pathogenesis by comparing patient-based model systems including iPSC-derived brain cells transplanted into

Assessment of depression and anxiety in young and old with a question-based computational language approach

Middle aged adults experience depression and anxiety differently than younger adults. Age may affect life circumstances, depending on accessibility of social connections, jobs, physical health, etc, as these factors influence the prevalence and symptomatology. Depression and anxiety are typically measured using rating scales; however, recent research suggests that such symptoms can be assessed by Middle aged adults experience depression and anxiety differently than younger adults. Age may affect life circumstances, depending on accessibility of social connections, jobs, physical health, etc, as these factors influence the prevalence and symptomatology. Depression and anxiety are typically measured using rating scales; however, recent research suggests that such symptoms can be assessed by

A System-Level Brain Model for Enactive Haptic Perception in a Humanoid Robot

Perception is not a passive process but the result of an interaction between an organism and the environment. This is especially clear in haptic perception that depends entirely on tactile exploration of an object. We investigate this idea in a system-level brain model of somatosensory and motor cortex and show how it can use signals from a humanoid robot to categorize different object. The model