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Fungal cells from Curvularia lunata were entrapped in a crosslinked polyacrylamide gel. The gel-cells obtained as granules were applied in the microbial transformation of Reichstein compound S leading to cortisol through an 11-β-hydroxylation step. Some kinetic studies of this conversion using gel-cells were carried out. In addition, it was shown that gel-cell gr

Influencers befinner sig i epicentrum av digitalisering och motstridiga arbetsideal. En industrikapitalistisk idealisering av (manligt) lönearbete dröjer sig kvar, men utmanas av en nyliberal (postfeministisk) tilltro till individens (inte minst kvinnans) drivkraft att som entreprenör styra livet mot framgång och lycka. Här undersöks hur tolv kvinnliga mikro-influencers förhåller sig till könade nThe feminine-coded work as an influencer has emerged as young women have transformed their personal life stories and self- representations on social media into digital businesses. Despite similarities with other forms of media production, the concept of work is vague, both in the public’s perception of what influencers do and for influencers themselves. It is challenging to differentiate between w

Den här artikeln ger ett exempel på hur medelålders kvinnor återupptäcker och uttrycker känslor i digitala medier, främst sexuell åtrå men också den glädje de känner bland likasinnade kvinnor i samma ålder. Det etnografiska exemplet är en grupp europeiska och nordamerikanska kvinnor i åldrarna 40-60 år som känner sexuell åtrå till den 20-årige TikTok-kändisen William White. White blev viral när haThis article provides an example of how middle-aged women rediscover and express emotions in digital media, mainly sexual desire but also the joy they feel among like-minded women of the same age. The ethnographic case is a community of European and North American women aged around 40 to 60 years who sexually desire 20-year-old TikTok celebrity William White. White went viral when he began lip-syn

Agarose is a well-established material in many applications of biochemistry and biotechnology. Agarose gels are used for electrophoresis of very large molecules such as DNA and agarose-based particles are used as chromatographic media for separation of all sorts of biomolecules, particularly proteins. Prominent commercial examples of agarose-based separation particles are exemplied by the brand na

Hydraulic force aids diastolic filling of the left ventricle (LV) by facilitating basal movement of the atrioventricular plane. The short-axis atrioventricular area difference (AVAD) determines direction and magnitude of this force. Patients with atrial septal defect (ASD) have reduced LV filling due to the left-to-right shunt across the atrial septum and thus potentially altered hydraulic force.

In this piece, which frames the special issue “Technocultural worldings,” we build on previous editions of commentary and criticism in this journal. We propose a theoretically anchored way to systematically approach the dynamic, multidimensional, and heterogeneous technocultural communities that have created their own worldings and are engaged in complex dialectical dynamics within the contemporar

AimsAtrial septal defects (ASDs) lead to volume-loaded right ventricles (RVs). ASD closure does not always alleviate symptoms or improve exercise capacity, which is possibly explained by impaired left ventricular (LV) haemodynamics. This study evaluated the effect of ASD closure in children using non-invasive LV pressure–volume (PV) loops derived from cardiac magnetic resonance (CMR) imaging and b

Youth gun violence has surged in Sweden recently. Quantitative studies have described the prevalence and geographical locations of gun violence, but little research has examined how perpetrators and victims themselves experience and make sense of guns. This article draws on ethnographic interviews with young men who have firsthand experience of gun violence in a criminal context. Drawing on narrat

I många av Svenska kyrkans församlingar firas mässa en eller flera gånger i veckan. Nattvarden är i högsta grad både aktuell och angelägen - och den engagerar. Med anledning av en ny kyrkohandbok 2017 och ett biskopsbrev om nattvarden 2020 har såväl gamla som nya frågor väckts, och diskussionen om nattvarden har intensifierats. Inte minst har förhållandet mellan teologin i de normativa dokumenten

Kapitlet diskuterar sex lutherska teologers syn på digitalt förmedlad nattvard.

Mycobacterium tuberculosis is dependent on cysteine biosynthesis, and reduced sulfur compounds such as mycothiol synthesized from cysteine serve in first-line defense mechanisms against oxidative stress imposed by macrophages. Two biosynthetic routes to L-cysteine, each with its own specific cysteine synthase (CysK1 and CysM), have been described in M. tuberculosis, but the function of a third put

The transpeptidase LtdMt2 catalyzes the formation of the (3-3) cross-links characteristic of the peptidoglycan layer in the Mycobacterium tuberculosis cell wall. Bioinformatics analysis suggests that the extramembrane part of the enzyme consists of three domains: two smaller domains (denoted as A and B domains) and a transpeptidase domain (the C domain) at the C-terminus. The crystal structures of

Effective treatment of tuberculosis is frequently hindered by the emerging antimicrobial resistance of Mycobacterium tuberculosis. The present study evaluates monocyclic β-lactam compounds targeting the mycobacterial cell wall remodeling. Novel N-thio-β-lactams were designed, synthesized, and characterized on the L,D-transpeptidase-2, a validated target in M. tuberculosis. The candidates were eval