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Introduction. Perioperative chemotherapy is the standard treatment for patients with locally advanced resectable gastric cancer. The prognostic relevance of MSI status in patients undergoing neoadjuvant chemotherapy remains unclear. Aim. To study the prognostic significance of MSI in gastric cancer patients undergoing perioperative CT. Materials and methods. The study included 173 patients with lo
Non-governmental organisations (NGOs) increasingly enter into “partnerships” with states to implement human rights, a phenomenon that has been studied both as a necessary inclusion of civil society in human rights practice, and as a slippery slope towards a neoliberal state retreat. What remains to be studied is how this partnership practice shapes the concepts of human rights and their duty beare
We all know that conflict creates displacement. Life becomes untenable in different ways, and people are forced to move; the majority ending up as internally displaced people within the nation-state, while others wind up in refugee camps in neighboring countries, and a very few seek asylum in faraway places. The recent war in Ukraine and the conflict in Syria since 2011 seemingly fit into this cla
The production of the W± bosons measured in p–Pb collisions at a centre-of-mass energy per nucleon–nucleon collision sNN = 8.16 TeV and Pb–Pb collisions at sNN = 5.02 TeV with ALICE at the LHC is presented. The W± bosons are measured via their muonic decay channel, with the muon reconstructed in the pseudorapidity region −4 < ηlabμ < −2.5 with transverse momentum pTμ > 10 GeV/c. While in Pb–Pb col
The total and differential Higgs boson production cross-sections are measured through a combined statistical analysis of the H → ZZ * → 4ℓ and H → γγ decay channels. The results are based on a dataset of 139 fb−1 of proton–proton collisions at a centre-of-mass energy of 13 TeV, recorded by the ATLAS detector at the Large Hadron Collider. The measured total Higgs boson production cross-section is 5
Purpose: Posterior fossa tumour surgery in children entails a high risk for severe speech and language impairments, but few studies have investigated the effect of the tumour on language prior to surgery. The current crosslinguistic study addresses this gap. We investigated the prevalence of preoperative word-finding difficulties, examined associations with medical and demographic characteristics,
Objectives: In India, cervical cancer is the most common cancer among women and makes up for up to 29% of all registered cancer in females. Cancer-related pain is one of the major distressing symptoms for all cancer patients. Pain is characterised as somatic or neuropathic, and the total pain experience is often mixed. Conventional opioids are the backbone of analgesic treatment but are most often
The volume provides a first-ever comprehensive account of the concept and the role of the family in EU law. It explores the family in EU law from four different angles. The first part of the book considers the philosophical and theoretical foundations of the family in the law in general, including the definition of the family under EU law. The second part provides an overview of the rights conferr
Close cooperation with third countries, especially in the EU’s neighbourhood, has erased a number of perceived boundaries between the EU and non-Member States. Whereas within the EU, family members are largely considered to be the natural beneficiaries of the free movement of persons with ensuing residence and social rights, it is less clear whether the same undisputed status of a family also appl
There is no official or universal definition for the concept of ‘family’. The absence of EU legislative competence in the substantive family law field means that there is no ‘EU family law’. Thus it is the individual EU legal instruments in different policy areas and the jurisprudence of the Court of Justice of the EU that demarcate, on an ad-hoc basis, the contours of the concept of ‘family’ and
In nuclear medicine, radiopharmaceuticals can be administered for both diagnostic and therapeutic purposes. In recent years, there has been an increasing interest in theragnostics, a strategy that combines both diagnosis and therapy. This can be achieved by using similar radiopharmaceuticals for imaging and radionuclide therapy, which enables highly personalised disease management. One theragnosti
This chapter addresses the question of the outer limits of the European Union’s (EU) internal market and its significance in the Union's foreign policy, especially in relations with the EU’s neighbouring countries. The internal market forms the core of European integration and has gained increased importance in the external context. Through an analysis of the relevance of the internal market withi
Many-electron systems undergo a collective Larmor precession in the presence of a magnetic field. In a paramagnetic metal, the resulting spin wave provides insight into the correlation effects generated by the electron-electron interaction. Here, we use dynamical mean-field theory to investigate the collective Larmor precession in the strongly correlated regime, where dynamical correlation effects
Recent studies have revealed a close connection between cellular metabolism and the chronic inflammatory process of atherosclerosis. While the link between systemic metabolism and atherosclerosis is well established, the implications of altered metabolism in the artery wall are less understood. Pyruvate dehydrogenase kinase (PDK)-dependent inhibition of pyruvate dehydrogenase (PDH) has been identi
Context. Exoplanets with orbital periods of less than one day are known as ultra-short period (USP) planets. They are relatively rare products of planetary formation and evolution processes, but especially favourable for characterisation with current planet detection methods. At the time of writing, 125 USP planets have already been confirmed. Aims. Our aim is to validate the planetary nature of t
Soft skills are becoming equally crucial as hard skills in today's labour market. In contrast to hard skills which are teachable typically through formal education, soft skills are non-technical and interpersonal, allowing individuals to be able to find and succeed in their studies, jobs, and professional life. Despite the increasing emphasis on soft skills, many university students are either una
Objectives To investigate factors associated with severe COVID-19 in people with psoriasis (PsO), psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA). Methods Demographic data, clinical characteristics and COVID-19 outcome severity of adults with PsO, PsA and axSpA were obtained from two international physician-reported registries. A three-point ordinal COVID-19 severity scale was define
The European Society of Organ Transplantation (ESOT) strives to promote equity, diversity, and inclusion (EDI) across all its activities. We surveyed the transplant community’s experiences and perspectives regarding EDI within ESOT as an organization and its educational activities, and research in general. A total of 299 respondents completed the questionnaire. About half agreed that ESOT’s Execut
Background: Gallbladder cancer (GBC) is rare but aggressive. The extent of surgical intervention for different GBC stages is non-uniform, ranging from cholecystectomy alone to extended resections including major hepatectomy, resection of adjacent organs and routine extrahepatic bile duct resection (EBDR). Robust evidence here is lacking, however, and survival benefit poorly defined. This study ass
