Chondroitin sulfate (CS)/dermatan sulfate (DS) proteoglycans are abundant on the cell surface and in the extracellular matrix and have important functions in matrix structure, cell-matrix interaction and signaling. The DS epimerases 1 and 2, encoded by Dse and Dsel, respectively, convert CS to a CS/DS hybrid chain, which is structurally and conformationally richer than CS, favouring interaction wi

The aim of this work was to compare the production of carotenes and ergosterol by red yeasts grown on pine lignocellulose substrates. The yeast strains Rhodotorula aurantiaca and Sporobolomyces shibatanus were grown on the liquid fraction of steam pretreated pine (210 °C, catalyst SO2). Biomass production on a pine hydrolysate was lower than on glucose. The highest content of carotenoids and ergos

Cellular homeostasis requires precise communication between various types of organelles. In particular, the communication between nucleus and semiautonomous organelles, mitochondria and chloroplasts, has received widespread attention. Communication from nucleus to other organelles is known as anterograde signaling, whereas communication from mitochondria or chloroplasts to the nucleus is known as

Conjugated polymers have been widely studied as flexible, versatile semiconductors in organic electronics. However, the material stability is one of the problems limiting their applications. Thus, understanding the degradation process of conjugated polymers is crucial. In this work, we monitored the chain scission of the model polymer MEH-PPV in chloroform solutions under different conditions by a

Combined U-Pb, O and Lu-Hf isotope analyses of detrital zircon grains from five major rivers in Ghana are used to investigate the growth and evolution of the Birimian terrane of the West African Craton. The majority of the analysed zircon yields supra-chondritic εHf values, suggesting derivation from primarily juvenile host magmas. Zircon grains from the Birim River in southwestern Ghana deviate f

Due to the high surface area to volume ratios leading to intensified heat and mass transfer rates, microreactors have been subject of interest for some time. Liquid-liquid two-phase flow is a very common phenomenon in microchannels. During the scale-up using a numbering-up approach, rectangular and square microchannels are preferred to circular microchannels in terms of easier integration of the f

Drawing from extensive fieldwork among graffiti writers in Sweden this article investigates gendered identity work and its consequences. It points to how potentially inclusive aspects of disembodied subcultural Performances-that identities are negotiated through the material representation of the writer rather than on basis of the physical body-nevertheless work exclu-dingly, especially so in term

Measurement of endwall heat transfer around a circular cylinder with a vortex generator pair has been investigated. Steady state liquid crystal thermography is adopted. Cylinders having two different height to diameter ratios have been employed. In one case, the cylinder has one end free in the flow and in the other case it has both ends attached on the walls. Local Nusselt numbers both upstream a

Previous research has proved Double-layer Microchannel Heat Sinks (MHSs) to be efficient ways to improve the cooling performance of electronic devices. However, the cooling potential of the upper working liquid cannot be fully utilized to cool down the substrate with the heated elements. In this sense, a concept of staggered double-layer MHS is proposed and designed. The parallel and counter flow

In most industrial product development projects, computer-based design analysis, or simply design analysis, is frequently utilized. Several design analysis process models exist in the literature for the planning, execution and follow-up of such design analysis tasks. Most of these process models deal explicitly with design analysis tasks within two specific contexts: the context of design evaluati

Thermal uniformity in the flow field plate of proton exchange membrane fuel cells (PEMFCs) is crucial for their power generating efficiency and reliability and therefore, has attracted much attention. The present numerical study is an attempt to optimize the flow channels via replacement of convectional zigzag continuous channels by tree-like bifurcated channels radially outwards. The numerical mo

Aim: To report basic epidemiological data concerning surgically treated childhood cataract in Sweden and Denmark. Methods: Data were derived from the Paediatric Cataract Register (PECARE), a binational, web-based surgical register representing Sweden and Denmark. All children operated before 8 years of age between 1 January 2007 and 31 December 2013 were included. Age-specific prevalence per 100 0

The rock-cut chamber tombs form a very small percentage of the rockcut tombs in Labraunda. The majority of these tombs, situated next to the sanctuary, were studied by Paul Åström in 1950 together with the sarcophagi; two improved from natural caves further from the sanctuary in both directions were found in a topographic survey conducted by Lars Karlsson in 2005, and finally one tomb at some dist

Background. Lowe syndrome (LS) and Dent-2 disease (DD2) are disorders associated with mutations in the OCRL gene and characterized by progressive chronic kidney disease (CKD). Here, we aimed to investigate the long-term renal outcome and identify potential determinants of CKD and its progression in children with these tubulopathies. Methods. Retrospective analyses were conducted of clinical and ge

Acute myeloid leukemia (AML) remains the most common form of acute leukemia among adults and accounts for a large number of leukemia-related deaths. Mutations in FMS-like tyrosine kinase 3 (FLT3) is one of the most prevalent findings in this heterogeneous disease. The major types of mutations in FLT3 can be categorized as internal tandem duplications (ITD) and point mutations. Recent studies sugge

Delayed-return foraging strategies connected with a sedentary lifestyle are known from Late Mesolithic Scandinavian settlements. However, recent evidence from the archaeological site of Norje Sunnansund, in south-eastern Sweden, indicates the presence of sedentism from the Early Mesolithic. By analyzing the faunal assemblage from Norje Sunnansund, patterns of delayed-return strategies were examine

Den österrikiske författaren och essäisten Robert Musil förser sociologin med väsentliga reflektioner och problemställningar. Musil för fram diskussioner som överskrider konventionella förståelser av moderniteten – sociologins generella analysobjekt. Artikeln fokuserar på två grundläggande kluster av frågor och begrepp i Musils arbete: människans gestaltlöshet och förhållandet mellan förnuft och kThe writings of the Austrian novelist and essayist Robert Musil provide sociology with vital problems and reflections. Indeed, Musil introduces discussions that extend conventional understanding of modernity – sociology’s general object of analysis. The article focuses on two major sets of questions in Musil’s work: the shapelessness of man and the relation between reason and sentiments. Both prob

Purpose To describe a large cohort of femtosecond laser–assisted cataract surgeries in terms of baseline characteristics and the related outcomes. Setting Eighteen cataract surgery clinics in 9 European countries and Australia. Design Prospective multicenter case series. Methods Data on consecutive eyes having femtosecond laser–assisted cataract surgery in the participating clinics were entered in

PurposeMonoallelic germ-line mutations in the BRCA1/FANCS, BRCA2/FANCD1 and PALB2/FANCN genes confer high risk of breast cancer. Biallelic mutations in these genes cause Fanconi anemia (FA), characterized by malformations, bone marrow failure, chromosome fragility, and cancer predisposition (BRCA2/FANCD1 and PALB2/FANCN), or an FA-like disease presenting a phenotype similar to FA but without bone

The purpose of this thesis is to evaluate and deduce the varied lifeways of Early Holocene foragers in southern Scandinavia. By taking an interdisciplinary approach, zooarchaeological data have been applied to the study of different aspects of Early and Middle Mesolithic subsistence, in order to frame a discussion concerning our current understanding of culture and life in early north European soc