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The predictive role of ultrasound-detected tenosynovitis and joint synovitis for flare in patients with rheumatoid arthritis in stable remission. Results of an Italian multicentre study of the Italian Society for Rheumatology Group for Ultrasound : The STARTER study

Objective: To define the role of ultrasound (US) for the assessment of patients with rheumatoid arthritis (RA) in clinical remission, including joint and tendon evaluation. Methods: A multicentre longitudinal study has been promoted by the US Study Group of the Italian Society for Rheumatology. 25 Italian centres participated, enrolling consecutive patients with RA in clinical remission. All patie

Genesis of hummocks found in tunnel valleys : an example from Hörda, southern Sweden

In the south-central sector of the former Fennoscandian Ice Sheet, imprints of the sub-glacial hydrological system are present as “glaciofluvial corridors,” formed by glacial meltwater at the ice–bed interface during the Bølling–Allerød warm period. Many of these are interpreted as tunnel valleys and are commonly characterized by hummocks on their valley floors. Contemporary ice sheets produce inc

How In-Service Experience Informs Design Modifications: A Case Study in Aero Engines

This research is triggered by a fundamental shift that is occurring in the manufacture and marketing of aero engines for commercial and defence purposes, away from the selling of products to the provision of services. Under the emerging ‘power by the hour’ paradigm, aero engines are effectively leased to the airlines, with the manufacturing company remaining responsible for their maintenance and r

Rapidity density distributions in 16O, 28Si, 32S, 197Au, and 208Pb induced heavy-ion interactions at 4A–200A GeV

The mass, energy, and centrality dependence of rapidity density distributions of relativistic, charged particles, produced in heavy-ion interactions in the energy range 4A–200A GeV, are investigated. The results indicate that the rapidity density distributions show systematic variations, which are used to predict distributions for Au+Au and Pb+Pb interactions in a model-independent way.

Hypereosinophilic syndrome in a child mosaic for a congenital triplication of the short arm of chromosome 8

An 11-year-old boy with mental retardation, malformations, and the mosaic karyotype 47,XY,+i(8p)/46,XY presented with fever, headache and petechiae. Peripheral blood WBC was 190 x 10(9)/l; and contained > 90% mature eosinophils. Cytogenetic analysis of the eosinophils revealed no aberrations except the constitutional karyotype. The patient was diagnosed as having a hypereosinophilic syndrome. Shor

Expanding the Social Dimension: Towards a Knowledge Base for Product-Service Innovation

The extension of businesses to incorporate the provision of function as a service in supplement to standalone products is an ongoing movement in manufacturing industry. In short, this means that the development intent should be guided by the need of ‘performance in use’ that the customer wants, e.g. thrust rather than an engine. By this, the established knowledge base challenges the development te