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Monoclonal antibodies represent an attractive approach for treatment of cancer. Phage display is a very powerful technique to display large antibody libraries, which can be used to isolate therapeutic antibodies. Panning of phage display libraries against cells generates complex antibody pools, and direct screening of such pools typically identifies high-frequent antibodies against highly expresse
Our bodies are defended by inborn protective strategies aimed against microorganisms, the so-called innate immune system. In this system, small peptide molecules characterized by positive charge serve as antibiotics. During allergic reactions, as exemplified hay fever and asthma, molecules named eotaxins are released. These attract a group of white blood cells named eosinophils to sites of inflamm
Leukemia involves uncontrolled proliferation of different types of blood cells. Accordingly, it is classified as Acute myeloid leukemia (AML), Acute lymphoblastic leukemia (ALL; which includes B cell and T cell – ALL), Chronic myeloid leukemia (CML) and Chronic lymphoblastic leukemia (CLL). Children are more prone to ALL while the other three forms of leukemia are more common in adults. Over the l
Implicit measures have started to gain attention in the attachment literature, as they offer a way to offer insight into information processing patterns, which may not be open to investigation otherwise. The aim of the current study was to investigate the role of supraliminal priming on ambiguous stimuli in individuals who reported high levels of attachment anxiety and avoidance, with a speci
Mitochondria are the main organelles in eukaryotic cells involved in energy production together with their role in other mechanisms including intermediate metabolism, calcium signaling and apoptosis. Due to their importance in the correct function of the cell, genetic mitochondrial disorders can present a wide variability of symptoms, such as epilepsy, skeletal and cardiac myopathy and intellectua
Money illusion was for a long time believed by most economists to be non-existent, despite previous large support for it, because it did not fit the neo-classical model of the rational individual. Using a survey to test students’ understanding of inflation as proxy for money illusion, this thesis aims to establish the existence of money illusion and develop an understanding of why some students ex
Abstract The retina is the inner most layer of the eye. It is responsible for conversion of light into an electrical signal that pass through the fibers of the optic nerve to the visual centers in the brain. Most of the neo-vascular retinal diseases lead to legal vision loss. Silver and gold nanoparticles have got a great interest in ocular research due to their anti-bacterial effects and their ab
På höghastighetslinjerna som planeras byggas i Sverige är det satt som mål att köra i 320 km/h. Att köra så pass mycket snabbare än det görs i dagsläget kräver ett kontaktledningssystem vars kontakttråd klarar av att vara stabilt och rakt uppspänt så att strömavtagaren kan gå jämt och inte orsaka att kontakttråden börjar svaja. Det resulterar i krav på att kontakttråden spänns upp med ett högre mo
This study relates to the transcription of foreign personal names into kanji in Japanese. The study is based upon a paper where Tokimoto & d’Arcais (2000) confirmed three working principles when natives transcribe place names written in hiragana: that jukugo reading will be preferred over juubako reading, that as few kanji segmentations as possible will be used, and that the names will be segm
The main goal of this project was to investigate how the thermal stability of two different types of polyhydroxyalkanoates; poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-4-hydroxybutyrate) were affected when washing them with acid solution. Initially, four different acids were used: citric acid, hydrochloric acid, formic acid and acetic acid. Citric acid gave the best results for both biop
Syftet med studien är att undersöka debatten om sex timmars arbetsdag mellan 2010-2017. Genom att använda diskursanalys undersöker jag hur debatten ser ut idag genom att analysera debattartiklar i svenska dagstidningar för att försöka förstå varför ingen vidare utveckling har skett vad det gäller arbetstidsförkortning i Sverige sedan 1973. Bourdieus teori om det politiska fältet erbjuder ett analy
This paper investigates empirical determinants of current account positions worldwide with a focus on the countries that started out as the European Monetary Union (including Greece that joined in 2001). Specifically, it addresses the question whether current accounts inside the Eurozone have reacted more sensitively to changes in macroeconomic fundamentals due to the facilitation of inter-country
Under 2016 sade ett stort antal barnmorskor upp sig kollektivt inom Region Skåne. Uppsägningarna var en protesthandling och del i en arbetsplatskonflikt som kretsade kring ökad återhämtning för att garantera barnmorskornas hälsa och patientsäkerheten. Uppsatsens syfte är att förstå hur och varför protesterna resulterade i kollektiva uppsägningar. Materialet består av kvalitativa intervjuer med bar
The small protein α-synuclein is strongly associated with Parkinson’s disease. This protein is found in inclusion bodies, named lewy bodies inside neurons of people suffering from the disease. α-synuclein is very abundant in the human brain, and its normal function is still elusive and unclear. The factors that trigger the accumulation and fibrillation of this protein into pathogenic inclusion bod
This thesis analyses the discourse of cultural heritage by taking the European Heritage Label (EHL) as a case study. The European Heritage Label is an organization established in 2011 by the European Union (EU) and created an application process for historical and cultural sites to be labelled as “European Heritage”. This thesis aims to critically analyse heritage as a concept that is used and pro
Today re-identification of persons in disjoint camera views demand large human effort and resources. There is a need of autonomous re-identification systems. This thesis has been focused on the development of autonomous re-identification systems based on recurrent neural networks able to analyze sequences of images of persons, enabling the possibility to filter out outliers within sequences and m
This paper investigates the spillover effects of siblings growing up with a brother or sister diagnosed with a chronic disease. I focus on the effect of having a sibling diagnosed with low birth weight on outcomes measuring educational attainment and achievement. The empirical analysis draws on data from the ’NLSY79 Child and Youth Survey’ and I find evidence of a significant negative effect on th
The goal of this thesis project was to develop an energy surveillance system for the Swedish production industry. The main problem this project sought to solve is that several Swedish industries are currently only able to measure the energy consumption of their entire facilities, as one big black box. They cannot determine the energy consumption of the individual machines within each and every pro
Sex chromosomes are chromosomes that carry vital sex-determining genes. Different sex determination systems and sex chromosomes have evolved from autosomes independently in different taxa; nevertheless, they share strikingly similar characteristics. Sex chromosomes undergo somewhat unique evolutionary processes due to paucity in recombination and transmission through only one of the sexes. As a re
Use of wholegrain foods has shown importance in terms of prevention of obesity and related comorbidities. Positive metabolic effects of wholegrain barley have been investigated with this regard. In the same line of research, this study aims to investigate the effects of barley kernel bread on glucose regulation, appetite and colonic fermentation in middle aged subjects. A randomized control trial
