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A new implementation of FLEXPART with Enviro-HIRLAM meteorological input, and a case study during a heavy air pollution event

We integrated Enviro-HIRLAM (Environment-High Resolution Limited Area Model) meteorological output into FLEXPART (FLEXible PARTicle dispersion model). A FLEXPART simulation requires meteorological input from a numerical weather prediction (NWP) model. The publicly available version of FLEXPART can utilize either ECMWF (European Centre for Medium-range Weather Forecasts) Integrated Forecast System

Widespread Pesticide Distribution in the European Atmosphere Questions their Degradability in Air

Risk assessment of pesticide impacts on remote ecosystems makes use of model-estimated degradation in air. Recent studies suggest these degradation rates to be overestimated, questioning current pesticide regulation. Here, we investigated the concentrations of 76 pesticides in Europe at 29 rural, coastal, mountain, and polar sites during the agricultural application season. Overall, 58 pesticides

Plasma neutrophil gelatinase-associated lipocalin independently predicts dialysis need and mortality in critical COVID-19

Neutrophil gelatinase-associated lipocalin (NGAL) is a novel kidney injury and inflammation biomarker. We investigated whether NGAL could be used to predict continuous renal replacement therapy (CRRT) and mortality in critical coronavirus disease 2019 (COVID-19). This prospective multicenter cohort study included adult COVID-19 patients in six intensive care units (ICUs) in Sweden between May 11,

Linear-quadratic level control for flotation through reinforcement learning

In the mining industry, flotation is a commonly used process to separate valuable minerals from waste rock in a concentrator. The rougher flotation is the first stage of the process and in Boliden AB’s concentrator at Aitik, it consists of two lines of four flotation cells each. In this paper we consider one line and the buffer tank upstream of it. Modeling this process step, and maintaining an up

Aromatic Polymethacrylates from Lignin-Based Feedstock: Synthesis, Thermal Properties, Life-Cycle Assessment and Toxicity

There is currently a great need for rigid, high-performance and processable bio-based polymers and plastics as alternatives to the fossil-based materials used today. Here, we report on the straightforward synthesis and polymerization of lignin-derived methacrylate monomers based on the methyl esters of syringic, vanillic, and 4-hydroxybenzoic acid, respectively. The corresponding homopolymethacryl

Immunsvar och inflammation vid Crohns sjukdom. Snart mojligt driva diagnostiken langre och utveckla mer specifika lakemedel

The chronic inflammation in Crohn's disease may be caused by aggressive response to bacterial antigens normal to the gut. Genetic and environmental factors modify the inflammatory response evoked by damage to the mucosal gut barrier. Genetic factors may also determine the subsequent course of chronic inflammation. Further elucidation of the pathogenesis might improve our understanding of the heter

Antigen presenting cells in autoimmune diabetes: phenotype, function and modulation by Linomide

Popular Abstract in Swedish Människor och djur utsätts ständigt för sjukdomsalstrande virus, bakterier och parasiter som finns i vår omgivning. Som skydd mot dessa har vi utvecklat ett immunförsvar. Detta har till uppgift att känna igen och eliminera dessa främmande, sjukdomsalstrande organismer (patogener), medan frisk, kroppsegen vävnad inte känns igen av immunsystemet. Immunsystemet består av kThe aim of this thesis was to better understand the role of antigen presenting cells (APC) in the development of diabetes in the nonobese diabetic (NOD) mouse. We have shown that DC and Mphi that infiltrate the islets of Langerhans produce tumour necrosis factor-a (TNF-a), a cytokine known to contribute to the pathogenesis in the early stages of diabetes development. TNF-a is produced from the ear