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Background Statistical analyses of clinical data are a cornerstone in understanding pathomechanisms of disorders. In rare disorders, cross-sectional datasets of sufficient size are usually not available. Taking AA amyloidosis as an example of a life-threatening rare disorder resulting from of uncontrolled chronic inflammation, we propose techniques from time series analysis to predict organ respon

Polycotylid and elasmosaurid plesiosaurs inhabited the Kristianstad Basin during Late Cretaceous (uppermost lower Campanian Belemnellocamax mammillatuszone) around 80 million years ago. The setting represents one of the most famous Mesozoic fossil sites in Scandinavia. The Kristianstad Basin fossils are generally fragmentary and isolated due to high-energy environments in a protected shallow innerPolycotylid and elasmosaurid plesiosaurs inhabited the Kristianstad Basin during Late Cretaceous (uppermost lower Campanian Belemnellocamax mammillatuszone) around 80 million years ago. The setting represents one of the most famous Mesozoic fossil sites in Scandinavia. The Kristianstad Basin fossils are generally fragmentary and isolated due to high-energy environments in a protected shallow inner

Critical StagesUnstable Grounds: Reconfigurations of Performance and PoliticsSpecial Issue, June 2021Gigi Argyropoulou and Stefanie SachsenmaierThis issue explores operations of performance during unstable conditions marked by socio-political, environmental, economic and further challenges. It is particularly interested in histories, reconfigurations and mutations of performance practice as it see

Introduction: Contact allergy to nickel (Ni) is a delayed-type hypersensitivity reaction mediated by Ni-reactive T cells producing the hallmark cytokines of several T-helper cell (Th) populations including IFN-γ(Th1), IL-4, IL-5 and IL-13 (Th2), and IL-17A (Th17). IL-22-expressing CD4+ cells, which could be either Th17 co-expressing IL-22 or Th22, expressing IL-22 in the absence of IL-17A, have al

BACKGROUND: Sotalol and dronedarone are both used for maintenance of sinus rhythm for patients with atrial fibrillation. However, while sotalol requires initial monitoring for QT prolongation and proarrhythmia, dronedarone does not. These treatments can be used in comparable patients, but their safety and effectiveness have not been compared head to head. Therefore, we retrospectively evaluated th

Stød is a syllable rhyme prosody that is realized as creaky voice, and its distributionis partly predictable. To examine listeners’ implicit knowledge of the complicatednature of stød distribution, we conducted a lexical decision task, investigating anirregularly behaving group of nouns in which stød distribution is unpredictable.We hypothesized that listeners would be the most surprised by deviat

Word formation processes frequently lead to systematic interactions between morphology and prosody (e.g., stress or speech melody). In this manner, the prosody on a word stem often changes when endings are added – either through inflection, derivation, or compounding. Native speakers exploit this relation between prosody and morphology during speech perception. On the one hand, they can use the pr

While there is growing awareness that knowledge of regional minority languages must be protected, assessing the vitality of such varieties is challenging due to the lack of assessment materials. Our contribution documents the creation and validation of LexVEN, a bimodal yes/no vocabulary task, with the purpose of assessing the proficiency of users of Venetan with receptive and/or productive skills

In many civil engineering problems, soil is stabilized by a combination of binders and water. The success of stabilization is evaluated using seismic tests with measured P-wave velocities. Optimization of process, laboratory testing and data modelling are essential to reduce the costs of the industrial projects. This paper reports the optimized workflow of soil stabilization through evaluated effe

We discovered nocturnal colour vision in the Asian giant honeybee Apis dorsata - a facultatively nocturnal species - at mesopic light intensities, down to half-moon light levels (approx. 10 -2 cd m -2). The visual threshold of nocturnality aligns with their reported nocturnal activity down to the same light levels. Nocturnal colour vision in A. dorsata is interesting because, despite being primari

Aims: Subclinical carotid atherosclerosis adds predictive value to traditional risk factors for cardiovascular diseases (CVDs). Systematic Coronary Risk Assessment 2 (SCORE2), an algorithm composed of traditional risk factors, is a state-of-the-art to estimate the 10-year risk of first-onset CVDs. We aim to investigate whether and how subclinical carotid atherosclerosis affects the performance of

Minimizing insecticide use, preventing vector diseases and facilitating biodiversity assessments are suitable applications of recent advances in photonic insect surveillance and entomological lidar. The tools also comprise a new window into fundamental aspect of the fascinating life and ecology of insects and their predators in situ. At the same time, it is evident that lidars are subject to finit

With the growing global population and the demand for new applications, the production of fossil-based plastics is continuously increasing. This has led to serious environmental concerns about the depletion of fossil resources, land and marine pollution, and generation of greenhouse gas emissions. These undesirable consequences of fossil-based plastics have sparked a significant interest in develo