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von Willebrand Factor D and EGF Domains is an evolutionarily conserved and required feature of blastemas capable of multi-tissue appendage regeneration
Regenerative ability varies tremendously across species. A common feature of regeneration of appendages such as limbs, fins, antlers, and tails is the formation of a blastema--a transient structure that houses a pool of progenitor cells that regenerate the missing tissue. We have identified the expression of von Willebrand Factor D and EGF Domains (vwde) as a common feature of blastemas capable of
Influence of Matrix When Tracing Cytostatic Drugs in Urban Wastewater: A Validated SPE-LC-MS/MS-Based Method
Cytostatic pharmaceuticals are not completely removed in wastewater treatment plants (WWTPs) and may affect aquatic ecosystems. Their quantification is challenging due to variations in wastewater characteristics, which influence analytical performance. An analytical procedure has been developed, based on solid-phase extraction and liquid chromatography coupled with tandem mass spectrometry, for th
IBE meets AIR : A framework for structured archaeological reasoning and digital reconstruction
The increasing use of digital tools in archaeology has vastly expanded our capacity to document and visualise the past, yet the reasoning that connects evidence to interpretation often remains implicit or undocumented. This paper addresses that gapby integrating Inference to the Best Explanation (IBE)—a philosophical model of hypothesis evaluation—into the Archaeological Interactive Report (AIR),
Gribshunden in Perspective : A Castle on the Sea
The royal Danish-Norwegian flagship Gribshunden, launched in 1485, was amongthe earliest northern European warships purpose-built to carry artillery. However, King Hans employed his vessel as far more than a weapons platform. The ship was his ‘floating castle’, fulfilling all the various purposes of a land redoubt. At its loss in 1495 enroute to a political summit in Kalmar, where Hans expected to
The Exceptional North : Past and Present Perspectives on Nordicness
On origin of coherence dynamics in biological complexes
Dynamic quantum effects in biological systems is a hotly debated question, which since recently has been experiencing renewed wave of broad attention [1]. This discussion was initiated by the application of the multidimensional spectroscopy techniques for investigating dynamics in biological complexes. Is nature really optimized to use non-trivial quantum effects, like dynamically evolving coheren
Om ni är tysta! : Fristående af-satser med uppmanande funktion i en idrottspedagogisk kontext
I denna artikel presenteras en närstudie av uppmaningar av typen Om ni är tysta, det vill säga om-inledda af-satser med uppmanande funktion. Syftet med studien är att undersöka funktionen hos uppmaningar som uttrycks med om-inledda af-satser i en idrottspedagogisk kontext. Materialet som ligger till grund för studien består av inspelningar från 26 idrottsaktivitetstillfällen. I detta material kan
Activation and Expansion of Age-Associated B Cells
När Försvarare Blir Fördärvare Vårt immunförsvar skyddar oss från infektioner och sjukdomar, och det förändras i och med att vi åldras. En speciell typ av cell går obemärkt förbi tills vi når en hög ålder, råkar ut för infektioner, eller drabbas av autoimmuna sjukdomar. De här cellerna kallas age-associated B cells (ABC) på engelska. Vissa forskare påstår att de har en betydande roll och kan föruAge-associated B cells (ABCs) are a novel subtype of B cells that accumulate with ageing, during infection, and in the progression of autoimmune diseases. Still, their exact phenotype and effector functions remain unknown. In this thesis, we aimed to provide an immunological characterisation of human ABC subsets by phenotyping them before and after in vitro stimulation and evaluating the alteratio
Functions of CD59 isoforms IRIS-1 and IRIS-2 in pancreatic β-cells
Type 2 diabetes is characterized by pancreatic β-cell dysfunction and insulin resistance. There are various studies about the contributing molecular mechanisms, and our recent findings show that the complement inhibitor Cd59 might play a non-canonical role in insulin secretion. Specifically, knock-out of Cd59 greatly inhibits glucose-stimulated insulin secretion. This, however, can be rescued by t
Characterization and Production of Medium-Chain-Length Polyhydroxyalkanoates (PHA) in Pseudomonas putida
Polyhydroxyalkanoates (PHAs) are microbial bio polyesters that offer a promising biodegradable alternative to petroleum-derived plastics. This thesis focuses on the production and characterization of medium-chain-length PHAs (mcl-PHAs) by Pseudomonas putida using octanoic acid as a carbon source. The main aim was to optimize key bioprocess parameters such as temperature, pH, dissolved oxygen (DO),
Charge carrier dynamics of quantum dot-sensitized ZnO nanowires probed by time resolved terahertz spectroscopy
Charge generation, injection and recombination in quantum dot-sensitized ZnO nanowires was probed using time resolved terahertz spectroscopy. The mobility spectrum at different representative pump-probe delays showed similar behavior during the injection time indicating free charges on the nanowire structures.
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Intermolecular hydrogen bonding between carotenoid and bacteriochlorophyll in LH2
We have studied van der Waals contacts of the carotenoid rhodopin glucoside (RG) with the bacteriochlorophyll pigments absorbing at 800 nm (B800) in the crystal structure of Rhodopseudomonas acidophila, and the hydrogen positions were determined from quantum chemical calculations at the Hartree–Fock (6-31G) level. We have found strong evidence for hydrogen bonding between the B800 BChl and the
Exciton Relaxation and Polaron Formation in LH2 at Low Temperature
Excited state dynamics of antenna complexes in an LH2-only mutant of the purple bacterium Rb. sphaeroides have been investigated by means of two-color femtosecond spectroscopy combined with computer simulations. Measurements of transient absorption spectra revealed a new spectral band in the stimulated emission region around 880 nm at 6 K. To simulate this new dynamic feature that appears withi
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Mapping Parallel Pathways of Energy Flow in LHCII with Broadband 2D Electronic Spectroscopy
Two-dimensional femtosecond broadband electronic spectroscopy was used to simultaneously probe parallel pathways of energy transfer in the major light harvesting complex of Photosystem II from plants. Sub-100 femtosecond relaxation between delocalized excitonic states on highly coupled clusters of chlorophylls and several hundred femtosecond to picosecond components of relaxation between clusters
Two dimensional optical spectroscopy of multi-chromophore protein complexes
Two-dimensional optical spectroscopy is used to probe electronic couplings and ultrafast dynamics in photosynthetic light-harvesting complexes. Data and analysis reveal contributions to line-broadening, signatures of weakly- and strongly-coupled chromophores, and pathways of energy transfer.
”De gängkriminella spelar efter regler som vi har gett dem”
Gender, liturgy and conversion in the Scandinavian Catholic diaspora in the 19th and 20th century
Liturgical life in today's Catholic Church in the Western world is dominated by women, alt-hough the priesthood remains reserved for men. Conservative critics speak of a feminization of worship life, which is said to be a consequence of the liturgical reform implemented after the Second Vatican Council in the 1960s. This movement gained traction in academic youth circles, and although women also j
