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Inflammation is a physiological response that may go uncontrolled and thereby develop in a chronic way. This seems to happen in many common diseases of autoimmune, degenerative, or allergic character. Rheumatoid arthritis (RA) is by definition a chronic disease with an autoimmune inflammatory attack on diarthrodial cartilaginous joints. The development of new treatment neutralizing cytokines invol
The major histocompatibility complex (MHC) has been studied in a multitude of mammals by now, but much less is known about its organisation and variation in other vertebrate species. The mammalian MHC is organised as a single gene cluster, but recent studies on birds suggest that this paradigm of MHC organisation has to be supplemented. The domestic chicken thus possesses two separate gene cluster
Popular Abstract in Swedish Avhandlingen studerar den svenska jordbruksomvandlingen under 1800-talet. Syftet är dels att analysera böndernas roll i jordbruksomvandlingen, dels att identifiera de egenskaper som de ledande bönderna, de agrara entreprenörerna, hade. Detta görs genom att studera ansökningar om skifte och kreditmarknadens utnyttjande i tre skånska socknar, Brösarp, Saxtorp och V. KarabThis study deals with the agricultural transformation in 19th century Sweden. The aims are: firstly, to analyse the peasants' role as entrepreneurs in the transformation of agriculture, and secondly, to identify the distinctive characteristics of the agrarian entrepreneurs by studying particular aspects of entrepreneurial dealings during the agricultural transformation in Scania between 1800 and 1
This study examined the role of neutrophil leukocytes for the antibacterial defense at mucosal infection sites. Urinary tract infection (UTI) was established by injection into the bladder lumen of Escherichia coli 1177, a fully virulent clinical isolate. Infection of C3H/HeN (lpsn, lpsn) mice recruited neutrophils into the urinary tract, and bacteria were cleared from kidneys and bladders. The neu
A Paleolithic diet has been suggested to be more in concordance with human evolutionary legacy than a cereal based diet. This might explain the lower incidence among hunter-gatherers of diseases of affluence such as type 2 diabetes, obesity and cardiovascular disease. The aim of this study was to experimentally study the long-term effect of a Paleolithic diet on risk factors for these diseases in
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Modern IC-engines produce more power per displaced volume and operate at higher combustion pressures and temperatures. In addition, engine structure materials such as aluminium and magnesium alloys, which are more sensitive to thermal loads, are more commonly used. These two parameters might lead to problems such as thermal fatigue, knock, high fuel consumption and emissions, performance loss, bor
In this thesis civil religion in the Czech Republic is studied throught the way it is expressed in the speeches of president Václav Havel. Earlier studies on civil religion have shown how civil religiion can be a latent phenomenon that is activated in times of societal change and crisis. In Havel's speeches, this is expressed by the emphasis put on democratic values, such as basic human rights, an
Until recently, the function of the fifth domain of the thermostable modular xylanase Xyn10A from Rhodothermus marinus was unresolved. A putative homologue to this domain was however identified in a mannanase (Man26A) from the same microorganism which raised questions regarding a common function. An extensive search of all accessible data-bases as well as the partially sequenced genomes of R. mari
Production of synthesis gas by catalytic reforming of product gas from biomass gasification can lead to catalyst deactivation by the exposure to ash compounds present in the flue gas. The impact of fly ash from biomass gasification on reforming catalysts was studied at the laboratory scale. The investigated catalyst was Pt/Rh based, and it was exposed to generated K2SO4 aerosol particles and to ae
Abstract in Arabic Abstract is not available
We report on the viscoelastic properties of dough and gluten (prepared by ultracentrifugation) after the flour lipids had been removed by solvents differing in polarity (chloroform, ethanol and diethylether). The extracted lipids were fractionated by thin layer chromatography. The flours differed in lipid composition after the extraction. Ethanol removed more polar lipids than the other solvents.
Asthma patients who continue to experience symptoms despite taking regular inhaled corticosteroids represent a management challenge. Leukotrienes play a key role in asthma pathophysiology, and since pro-inflammatory leukotrienes are poorly suppressed by corticosteroids it seems rational to add a leukotriene receptor antagonist (LTRA) when a low to moderate dose of inhaled corticosteroids does not
Aim The aim of this work was to estimate on a regional scale the effects of nitrogen (N) deposition and harvest intensity on N-budgets in forest soils as a basis for strategies of emission reduction and sustainable forest management methods. Location The calculations were applied to Sweden, a country with a managed forest area of 23 x 10(6) ha. Methods Mass balance calculations, including N-deposi
