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Acoustophoresis in tumor cell enrichment

This chapter outlines the opportunities and current developments of label-free separation of circulating tumor cell (CTC) from blood cells using acoustophoresis. It describes two platforms that have been developed to enable subsequent evaluation of acoustophoresis in clinical settings. All nucleated cells in suspension flow along a microchannel wherein the cells are exposed to an acoustic field. T

Climate, peace, and conflict—past and present: Bridging insights from historical sciences and contemporary research

Concern has risen that current global warming and more frequent extreme events such as droughts and floods will increase conflict around the world. This concern has spurred both social science research on contemporary climate, peace, and conflict as well as research in the historical sciences on past climate, weather, warfare, and violence. This perspectives article compares these two fields of sc

Integrated approach to investigate groundwater nitrate nitrogen pollution and remediation simulation in Shimabara Peninsula, Nagasaki, Japan

Groundwater is the general source of drinking water in the Shimabara Peninsula, Nagasaki, Japan, and consequently, occurring nitrate nitrogen (NO3-N) pollution in the groundwater is a significant problem. Although various countermeasures have been implemented, nitrate nitrogen concentrations remain serious. Therefore, it is necessary to evaluate effects of different potentially effective counterme

Randomised controlled trial to compare the efficacy of integrated cognitive-behavioural therapy (COPE-A) for substance use and traumatic stress among adolescents and young adults delivered via telehealth versus in person: trial protocol

Introduction Emerging research indicates that integrated treatment of co-occurring post-traumatic stress disorder (PTSD) and substance use disorder can be effective among adolescents and young people. However, various barriers exist to young people accessing evidence-based treatments. Telehealth offers an opportunity to address these barriers and provide a scalable and accessible alternative to in

Shifting Horizons: The Evolving Geography of Uzbek Labor Migration to the European Union

This paper explores recent trends in Uzbek labor migration, with a focus on the growing role of the European Union as a destination. While Russia remains the largest host country, ongoing diversification has led to a notable increase in migration to EU member states, particularly for employment. Drawing on official statistics and fieldwork, the study highlights rising numbers of Uzbek migrants in

Knowing to care and caring to know : Negotiating modes of care and knowledge in peatland restoration in Denmark

Peatlands have become a silver bullet in climate mitigation policy globally. Restoring and rewetting agricultural peatlands is key for meeting reduction targets within the agricultural sector. But unlike other sectors, change rests on the decisions of individual farmers. In Denmark, a political aim towards restoring 100.000 hectares of agricultural peatlands by 2030 is challenged by uncertainty, d

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The Iran-Israel war, launched on June 13, 2025, marked a historic intelligence failure for the Islamic Republic. Israel’s surprise offensive devastated Iran’s military leadership and exposed deep systemic flaws in its counterintelligence apparatus. The strategic collapse of the regime now raises urgent questions about its survivability and the necessity of regime change.

Older persons' experiences with wearable sensor-based fall risk screening in free-living conditions - a qualitative study

BACKGROUND: Falls are common among older persons and can have a major impact on their lives. Wearable sensors used in free-living conditions (moving naturally in one's daily living environment) can be used to predict falls and fall risks. To understand if using the wearable sensors is an acceptable way for older persons to be screened for fall risks, it is important to have knowledge of older pers

Synthesis and evaluation of CuO and Co-doped CuO nanofibers as electrocatalysts for nitrate reduction to ammonia

This master thesis investigates the synthesis, structural characterization and electrochemical performance of copper(II) oxide (CuO) and cobalt-doped CuO nanofibers as electrocatalysts for the electrochemical nitrate reduction reaction (NO3-RR). The overarching aim is to assess their potential for sustainable ammonia production under ambient conditions. A series of exploratory synthesis trials rev

Characterizing GME-Dimension through Critical Visibility in Noisy Supersinglet States

Entanglement in quantum mechanics manifests in two distinct forms, either between many qubit systems or two high-dimensional quantum systems with entangled degrees of freedom. These two classifications are well established. However, recent strides have been made to unify these two conditions as quantum technologies evolve further. The GME-dimension quantifies the entangled degrees of freedom in a

LDMX HCal prototype data analysis

The Light Dark Matter eXperiment (LDMX) is a planned missing momentum and energy experiment at SLAC, the purpose of which is to produce dark matter through production at an accelerator. A key theoretical process making this possible is called "dark bremsstrahlung," where an electron scattering off a nucleus produces a dark photon instead of a Standard Model photon. LDMX aims to detect da

Vad är grejen med språk? – En explorativ studie om fysiklärare på gymnasiets bild och inställning till språk i fysik

Detta arbete är en explorativ studie om svenska fysiklärare på gymnasiet och hur de ser på språkets roll inom fysikämnet samt hur de ställer sig som lärare i rollen att behöva vara en lärare som undervisar språkliga element. Studien genomfördes med hjälp av kvalitativa intervjuer där totalt fyra lärare med varierande erfarenhet som fysiklärare intervjuades. Resultaten analyserades med hjälp av ett

CFD-Based Methodology for Float Design Evaluation in Filling Systems

This thesis presents a simulation-driven methodology for evaluating float design in aseptic filling machines, with the objective of reducing surface instabilities and air entrainment that contribute to splashing during the filling of viscous food products. The study was conducted in collaboration with Tetra Pak and focuses on understanding how float geometry, particularly mass and radius, affects

Grass is not always greener: the management and governance of non-native plants in Antarctica

Non-native plants are a growing problem in Antarctica. By encroaching on native plants’ habitats, they risk leaving the last frontier of authentic wilderness irreversibly altered. As the climate continues to change and more people visit Antarctica, non-native plants’ spread and impacts are expected to become more severe. The Protocol on Environmental Protection to the Antarctic Treaty prohibits in

Meaning and Cognition : A Unified Approach to Meaning-Making

Sociological approaches to culture are divided into interpretive, representational, and embodied perspectives, each grounded in distinct ontologies and causal logics derived from realism and interpretivism. This article aims to bridge embodied and representational approaches and their concomitant philosophies of science. It proposes a concept of meaning-making that unifies representational approacSociological approaches to culture are divided into interpretive, representational, and embodied perspectives, each grounded in distinct ontologies and causal logics derived from realism and interpretivism. This article aims to bridge embodied and representational approaches and their concomitant philosophies of science. It proposes a concept of meaning-making that unifies representational approac

Revealing teaching quality through lesson semantics : A GPT-assisted analysis of transcripts

BACKGROUND: Existing conceptions of teaching quality assume that classroom interactions serve as the foundation for effective teaching. The resulting data necessitates analytical approaches capable of extracting the semantics of these interactions.AIM: This study investigates whether and to what extent lesson semantics provide insights into teaching quality (i.e., cognitive engagement, encourageme

Considerations in the clinical use of amyloid PET and CSF biomarkers for Alzheimer's disease

Amyloid-β (Aβ) positron emission tomography (PET) imaging and cerebrospinal fluid (CSF) biomarkers are now established tools in the diagnostic workup of patients with Alzheimer's disease (AD), and their use is anticipated to increase with the introduction of new disease-modifying therapies. Although these biomarkers are comparable alternatives in research settings to determine Aβ status, biomarker

A Federated Data Analysis Approach for the Evaluation of Surrogate Endpoints

In clinical trials, surrogate endpoints, that are more cost-effective, occur earlier, or are more frequently measured, are sometimes used to replace costly, late, or rare true endpoints. Regulatory authorities typically require thorough evaluation and validation to accept these surrogate endpoints as reliable substitutes. To this end, the meta-analytic framework is considered a very viable approac

Minimum inhibitory concentration distribution of Mecillinam in clinical Staphylococcus saprophyticus isolates from Europe

Objectives: Staphylococcus saprophyticus (S. saprophyticus) is the second most common bacteria causing uncomplicated urinary tract infections (UTIs). It is considered non-susceptible to mecillinam, with no defined breakpoint and only few available minimal inhibitory concentration (MIC) observations. However, this consideration does not correlate with clinical outcome. With this study, we aimed to