Creatinine is a widely used clinical biomarker in adult and pediatric patients to estimate kidney function and glomerular filtration rate. There are however few recent studies that have addressed method performance in the creatinine range relevant for children. This study aimed to describe measurement performance in the pediatric concentration range by comparing commonly used enzymatic methods on

Diffusion magnetic resonance imaging (dMRI) is a powerful non-invasive technique for probing tissuemicrostructure. While highly sensitive, conventional dMRI methods suffer from low specificity, due in part toexperimental designs that conflate multiple contrast mechanisms. This thesis aims to address these limitations bydeveloping advanced time-dependent dMRI techniques to disentangle competing sou

The adoption of Digital Human Resource Management (DHRM) is increasing exponentially in the present market landscape; organizations are curious to digitalize human resource practices and enhance organizational performance. The purpose of the presented research is to assess various factors impacting DHRM adoption. The presented study is grounded in social exchange theory and dynamic capability theo

AimTo fully take advantage of blood test results, comparative data are required. Today, the reference interval is a commonly used concept. This review aims to summarise the current state of reference intervals, focusing on infants.MethodsLiterature on reference percentiles (birth to 12 months of age) published from January 1950 until November 2024 was reviewed. Search terms comprised paediatric, i

While the importance of breastfeeding on the developing infant gut microbiota has been established, few studies have compared the effect of breastfeeding duration on infant gut microbiota development. In this pilot study, we included 23 infants, divided into 4 groups to compare the effect of breastfeeding duration for first 4 (BreastFed_4) or 8 weeks (BreastFed_8) compared to exclusive breast

The coefficient of friction (COF) and wear are critical parameters in assessing disc brake performance. However, their study is challenging due to their interdependence on contact pressure, sliding velocity, temperature, and material composition. The complex contact interactions between brake pads and discs involve the continuous formation and destruction of mesoscopic contact plateaus, which

The possibility of imaging single proteins constitutes an exciting challenge for x-ray lasers. Despite encouraging results on large particles, imaging small particles has proven to be difficult for two reasons: not quite high enough pulse intensity from currently available x-ray lasers and, as we demonstrate here, contamination of the aerosolized molecules by nonvolatile contaminants in the soluti

We use extremely bright and ultrashort pulses from an x-ray free-electron laser (XFEL) to measure correlations in x rays scattered from individual bioparticles. This allows us to go beyond the traditional crystallography and single-particle imaging approaches for structure investigations. We employ angular correlations to recover the three-dimensional (3D) structure of nanoscale viruses from x-ray

Single-particle diffraction from X-ray Free Electron Lasers offers the potential for molecular structure determination without the need for crystallization. In an effort to further develop the technique, we present a dataset of coherent soft X-ray diffraction images of Coliphage PR772 virus, collected at the Atomic Molecular Optics (AMO) beamline with pnCCD detectors in the LAMP instrument at the

Single particle diffractive imaging data from Rice Dwarf Virus (RDV) were recorded using the Coherent X-ray Imaging (CXI) instrument at the Linac Coherent Light Source (LCLS). RDV was chosen as it is a well-characterized model system, useful for proof-of-principle experiments, system optimization and algorithm development. RDV, an icosahedral virus of about 70 nm in diameter, was aerosolized and i

Background: Respiratory symptoms are common in the general adult population. Increased burden of respiratory symptoms may increase the risk of mortality. We assessed the association between respiratory symptom clusters and mortality. Methods: Participants were derived from two population-based Swedish adult cohorts (N = 63,060). Cluster analysis was performed with Locality Sensitive Hashing (LSH)-

This paper proposes an alternative semi-analytical Fourier modal method adapted for general periodic anisotropic gratings made of dielectrics with moderate to low index profiles corresponding to materials ranging from conventional dielectric 3D printing materials to ceramic materials. The proposed method is closely related to classical Rigorous Coupled-Wave Analysis built on scattering matrices, h

Serial crystallography (SX) at both X-ray free-electron lasers (XFELs) and synchrotrons offers the possibility to collect data at non-cryogenic temperature almost radiation damage free and enables time-resolved crystallography of irreversible reactions. The necessary steady delivery of new micron-sized crystals of biological macromolecules sets it apart from traditional single crystal macromolecul

ObjectiveRecent studies suggest that immigrants trade youth when partnering with members of the White majority population. This study contributes to this emerging literature by examining whether this trade should be understood as differential treatment based on immigrant status or as a broader dynamic of racial preferences in the marriage market.MethodsThis study compares age gaps in unions of int

This study investigates the ignitability of hydrogen in an optical heavy-duty SI engine. While the ignition energy of hydrogen is exceptionally low, the high load and lean mixtures used in heavy-duty hydrogen engines lead to a high gas density, resulting in a much higher breakdown voltage than in light-duty SI engines. Spark plug wear is a concern, so there is a need to minimise the spark energy w

We propose a dynamical model depicting nitrogen (N2) fixation (diazotrophy) in a unicellular cyanobacterium, Crocosphaera watsonii, grown under light limitation and obligate diazotrophy. In this model, intracellular carbon and nitrogen are both divided into a structual pool and a storage pool. An internal pool that explicitly describes the nitrogenase enzyme is also added. The model is successfull

I en svår tid kan ett enkelt digitalt upplägg innebära både glädje och lättnad för många människor. Det skriver forskarna Tove Harnett, Sofi Fristedt och Håkan Jönson tillsammans med Eva Wiman, anhörigrådgivare och verksamhetsansvarig vid Malmö anhörigförening.