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EU State Aid Policy: Concealed Transfer of Competences?

This chapter concerns the role of competition policy, and in particular EU State aid rules, in the European integration process. The Treaty of the Functioning of the European Union contains a ban on State aid. However, this ban is not without exceptions. Through a centralized system, there is scope for exceptions in many policy areas. This also applies to areas where the member states are reluctan

The immune microenvironment in mantle cell lymphoma : Targeted liquid and spatial proteomic analyses

The complex interplay of the tumour and immune cells affects tumour growth, progression, and response to treatment. Restorationof effective immune response forms the basis of onco-immunology, which further enabled the development of immunotherapy. Inthe era of precision medicine, pin-pointing patient biological heterogeneity especially in relation to patient-specific immunemicroenvironment is a ne

A review of data-driven approaches to predict train delays

Accurate train delay prediction is vital for effective railway traffic planning and management as well as for providing satisfactory passenger service quality. Despite significant advances in data-driven train delay predictions, it lacks of a systematic review of studies and unified modelling development framework. The paper reviews existing studies with an explicit focus on synthesizing a structu

Using Information Criteria to Select Averages in CCE

In the interactive effects panel data literature information criteria are commonly used to consistently determine which of the estimated principal components factors to include. The present paper shows that the same approach can be applied to factors estimated by taking the cross-sectional averages of the observables, as prescribed by the popular common correlated effects (CCE) approach. This shou

Antecedents to bounce forward : a case study tracing the resilience of inter-organisational projects in the face of disruptions

Inter-organisational projects depend on stakeholder interactions and joint decision-making to perform and continually adjust to variations. This paper examines the emergence of transformative resilience (i.e., dynamic project capabilities to pursue fundamentally new strategies and practices) when facing external disruptions. A process-orientated case study was conducted within a culturally diverse

Towards Conceptualizing and Modelling Critical Flows - A Three-Tier Modelling Framework with a Swedish Example

Continuous access to flows of goods and services, such as energy, transport, information, and food, is essential and the basis for functioning modern societies. Hence, they are critical and need to be secured. Mega-trends such as climate change, changing geopolitical environment, hybrid- and cyber threats, and rapid technological advances come with new challenges and emerging threats to securing f

Citizen science initiatives increase pollinator activity in private gardens and green spaces

Wild insect pollinators are essential to cultivated and natural ecosystems globally. Today, many pollinator species are declining. One reason is a general lack of flowering habitats at landscape scales. However, urban areas, including private gardens, may provide flowers, and constitute beneficial habitats for pollinators. Here, we evaluate the ecological outcomes of a citizen science campaign run

INFORM: INFrared-based ORganizational Measurements of tumor and its microenvironment to predict patient survival

The structure and organization of a tumor and its microenvironment are often associated with cancer outcomes due to spatially varying molecular composition and signaling. A persistent challenge is to use this physical and chemical spatial organization to understand cancer progression. Here, we present a high-definition infrared imaging–based organizational measurement framework (INFORM) that lever

Identification of novel autoantigens as potential biomarkers in juvenile idiopathic arthritis associated uveitis

BACKGROUND: Many children with juvenile idiopathic arthritis (JIA) have autoantibodies, targeting nuclear components (anti-nuclear antibodies, ANA). ANA in JIA is associated with uveitis, an eye inflammation which may cause permanent vision impairment if not detected and treated. However, ANA-testing is neither specific nor sensitive enough to be a clinically reliable predictor of uveitis risk, an