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BackgroundThere has been an increased focus on clinical practice that may reduce severe perineal trauma due to awareness of the associated morbidity. Knowledge regarding the best practice to reduce these injuries is limited. Collegial midwifery assistance during the second stage of labour that involves an additional midwife being present has recently been implemented into many Swedish birth units

Sustainability science (SS) is diverse field of problem-driven and solution-oriented research that is still developing. The further maturation of the field relies on its practitioners formulating alternative paradigms to use-inspired knowledge production to facilitate comparison and reasoned judgment on what constitutes scientific best practices. In this short article, we flag several blind spots

Objective: To explore associations between four methods assessing long-term neurocognitive outcome after out-of-hospital cardiac arrest and early hypoxic-ischemic neuronal brain injury assessed by the biomarker serum neurofilament light (NFL), and to compare the agreement for the outcome methods. Methods: An explorative post-hoc study was conducted on survivor data from the international Target Te

Objectives: MRI-only radiotherapy (RT) provides a workflow to decrease the geometric uncertainty introduced by the image registration process between MRI and CT data and to streamline the RT planning. Despite the recent availability of validated synthetic CT (sCT) methods for the head region, there are no clinical implementations reported for brain tumors. Based on a preceding validation study of

BACKGROUND: There is a lack of research regarding factors promoting recovery during the workday and effective interventions. OBJECTIVE: To evaluate how different intervention activities may impact employees' experiences of recovery at the workplace. METHODS: Customized intervention activities based on qualitative results and a participatory approach were integrated among the employees at six prima

Life-long production of blood from hematopoietic stem cells (HSC) is a process of strict modulation. Intrinsic and extrinsic signals govern fate options like self-renewal – a cardinal feature of HSC. Bone morphogenetic proteins (BMP) have an established role in embryonic hematopoiesis, but less is known about its functions in adulthood. Previously, SMAD-mediated BMP signaling has been proven dispe

Structural changes and neuropathology in the hypothalamus have been suggested to contribute to the non-motor manifestations of Huntington’s disease (HD), a neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin (HTT) gene. In the present study, we investigated whether transcriptional changes would be part of hypothalamic pathology induced by the disease-causing huntingtin (H

While family members tend to have similar labor market outcomes, measuring the contribution of behavioral spillovers is difficult. To identify spillovers between brothers, we exploit Denmark's largest random assignment of young men—to eight months of military service, where service status of brothers is correlated, but draft lottery numbers are not. We find average spillovers of elder brother serv

Garden escapes of Acer campestre spread as a cryptic invading gene pools and challenge the conservation of a unique ancient population in southern Scandinavia. The native gene pool consists of just 34 individuals and is listed as critically endangered. This population is more than 150 years old and represents a unique diorama into an almost extinct genetic diversity of the early 19th century. That

This mini-review presents the structural investigations of the self-assembled peptide nanotubes using X-ray scattering techniques. As compared to electron microscopy, scattering methods enable studies of nanotubes in solution under the appropriate physicochemical conditions and probe their formation mechanism. In addition, a combination of X-ray scattering methods allow the elucidation of structur

Homelessness and other forms of destitution among asylum-seeking migrants are currently on the rise across Europe, as migrants’ access to social rights, including housing, has been restricted through repressive migration policies, fuelled by the welfare nationalism and chauvinism that surge among European states. This article explores the largely overlooked homelessness experienced by migrants seeHomelessness and other forms of destitution among asylum-seeking migrants are currently on the rise across Europe, as migrants’ access to social rights, including housing, has been restricted through repressive migration policies, fuelled by the welfare nationalism and chauvinism that surge among European states. This article explores the largely overlooked homelessness experienced by migrants see

Severe Covid-19 has a high mortality rate. Vital organ dysfunction results from pathophysiological self-amplifying loops of innate immunological hyperactivation, cytokine release, complement deposition, endothelial damage, and macro- and microvascular thromboembolism. Resulting alveolar exudation and pulmonary capillary thromboembolism lead to ventilation-perfusion mismatch, considered to be a pri