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Antibiotikaresistens är ett fenomen där bakterier utvecklar motståndskraft mot antibiotika. Detta kan leda till svåra infektioner och sjukdom i brist på behandlingsalternativ. Det är därför viktigt att utveckla nya typer av antibiotika som angriper bakterier på sätt som skiljer sig från tidigare varianter av antibiotika. En sådan ny typ av metod utvecklades i denna studie genom att stödja immunförAntibiotic resistance is a threat that could result in severe consequences for the public health. The synthesis of new antibiotics is therefore increasingly more important. Sialic acid is a sugar which aids bacterial growth, but the opposite effect could occur if bacteria were prevented from utilizing this sugar. This could be achieved through inhibition of pmSiaT, a protein which transports siali

With the 25-year anniversary of the Öresund bridge, questions can be posed: how has the region benefited from the increased integration? What opportunities and problems can the individuals of this region tell of? This thesis contributes to the discussion regarding identity creation in border cultures. The results presented in this study show how new identities are shaped out of necessity through t

Forskningsfråga: Hur relaterar kassakonverteringscykelns komponenter till lönsamhet i europeiska storföretag under perioden 2017–2023 och vilka förklaringar kan ges till de observerade sambanden? Metod: Studien baseras på en deduktiv ansats och en kvantitativ metod för att besvara frågeställningen. Två separata regressionsanalyser genomförs och analyseras med hjälp av tidigare empirisk forskning

On not sharing ones home with ones partner: The gendered experience of women in LAT relationships in Sweden and Austria. This thesis explores the gendered experiences of women in Living Apart Together (LAT) relationships. It focuses on how LAT as a relational form is negotiated within the contested space of intimacy and coupledom, that is shaped by cultural norms and societal expectations around c

This thesis explores how employees influence and experience Corporate Sustainability (CS) strategy implementation at Sony. Through interviews with twelve staff members across departments, it highlights misalignment between CS goals and daily roles, and the need for clearer guidance. Bottom-up initiatives offer promise but need institutional backing. The study recommends improved communication, tra

Denna studie undersöker möjligheten att använda geotermisk energi till fjärrvärmesystemet i Jönköping. Med ökande krav på lägre utsläpp från fjärrvärmeanläggningar kan geotermi som värmekälla till fjärrvärmenätet vara ett intressant alternativ till avfallsförbränning eller biobränslen. De lokala förutsättningarna för geotermisk energi har kartlagts med fokus på det sandstenslager som finns i centrThis study investigates the potential of using geothermal energy for the district heating system in Jönköping, Sweden. With an increasing demand for lower emissions from district heating plants, geothermal energy as a heat source for district heating networks may be an interesting alternative to waste incineration or biofuels. The local conditions for geothermal energy have been investigated focus

87 % av våra använda kläder bränns eller dumpas – kan digitala produktpass för textilier vända trenden? För att minska förbränningen och dumpningen av använda textilier måste återanvändningen och återvinningen öka. Digitala produktpass för textilier har möjlighet att stötta i dessa aktiviteter, men det finns oklarheter som måste redas ut för att produktpassen ska kunna användas på bästa sätt. ViThe textile industry generates large amounts of waste, most of which is incinerated or landfilled. To enhance circular practices, the Ecodesign for Sustainable Products Regulation will introduce digital product passports (DPPs) in the EU. The passports will collect data on textiles throughout their value chain and are expected to become mandatory by 2027. The existing research on the DPP usability

This thesis explores how born-sustainable small and medium-sized enterprises (SMEs) in the fashion industry can balance and improve the implementation of sustainability and profitability. It develops a cross-cultural analysis, comparing Brazil and Scandinavia (namely Sweden and Denmark). A constructionist framework is adopted in order to analyse culture, sustainability, and profitability with a su

Cancer orsakar en sjättedel av alla dödsfall världen över. Varje år diagnostiseras omkring 20 miljoner människor, varav 400 000 är barn. De läkemedel som finns idag är inte alltid effektiva och dessutom finns det inte läkemedel för alla typer av cancer. Det är därför väsentligt att det konstant utvecklas nya cancerläkemedel. I våra celler finns proteinet galektin som är inblandat i många av cellToday, galectin-1 poses as an interesting drug target for novel cancer treatments, due to its involvement in cancer progression. MD simulations with a 3-(thiazole-triazolyl)-galactoside, a good galectin-1 inhibitor, and the target protein reveals an unoccupied binding pocket close to the inhibitor. This project therefore aims to perform a bio-orthogonal C-H functionalisation on position 5 of its t

Inverter-based resources are playing an increasingly important role in power systems. However, the ability of inverter-based resources to deliver short-circuit currents is very limited, and often lies in the range of 1.2 to 2 p.u. for current power modules. This range is considerably lower when compared to that of synchronous generators, yielding short-circuit currents between 6 to 8 p.u. The diff

The coupled climate and nature crisis requires rapid mitigation that does not compromise biodiversity. Forests have the potential to improve environmental objectives in synergies depending on management. To better understand the motivations behind forest management practices among non-industrial private forest (NIPF) owners in Sweden, this study conducted a cross-sectional comparative analysis wit

In order to solve planetary health, the human-nature relationship has to be understood in more detail. Therefore, the current study aimed to validate and assess construct, convergent, divergent, and predictive validity of the Nature Disconnectedness Scale. Using data from 312 participants in Sweden, confirmatory factor analyses found support for a structure consisting of three dimensions and eight

This thesis explores how a sustainable future for the Sinharaja forest reserve might be achieved. Sinharaja is the largest remaining tract of ancient rainforest in Sri Lanka, home to a diverse array of flora and fauna, the majority of which are endemic. While conservation efforts initiated by the Sri Lankan government provide a promising framework for protecting this unique landscape, challenges

Vatten är nödvändigt för att den mänskliga kroppen ska fungera. För att vattnet ska kunna transporteras in och ut ur cellerna behöver det komma igenom cellmembranet, vilket det bland annat gör via en särskild klass av proteiner som fungerar som vattenkanaler – akvaporinerna. Akvaporiner finns överallt i vår kropp och är viktiga för många biologiska funktioner såsom metabolism och återfuktning av hAquaporins (AQPs) are a family of transmembrane proteins, mainly mediating water transport over the cell membrane in various parts of the body. The aquaporins AQP3 and AQP7 are both part of the subfamily aquaglyceroporins, which apart from water conduct small non-polar solutes such as glycerol. AQP3 overexpression or malfunction has been connected to skin and lung cancer and potential AQP3 inhibit

An optical system for digital light processing car headlamps was designed and optimized in this project. The specifications include five lens elements and a field of view of 15 degrees horizontally and 7.5 degrees vertically. The system consists of an illumination module and a projection lens assembly. A high-brightness LED source and a rectangular light integrator ensure uniform illumination on t

Purpose: This study aims to contribute to the understanding of how job-seekers relate their negative recruitment process experiences to brands. Design/Methodology/Approach: This study adopts a qualitative approach using semi-structured interviews, conducted with thirteen current university students actively seeking employment in degree-requiring fields. The data is abductively analysed through th

This thesis explores a hybrid procedural animation framework that combines physics-based constraints with artistically tunable parameters to generate diverse, real-time character locomotion. Addressing the limitations of traditional keyframing and opaque data-driven methods, the system employs a hierarchical parameter set-ranging from high-level style descriptors (e.g., "energy level") t

The primary task of child forensic interviewers is to secure evidence without causing the child discomfort. Evidence obtained through incorrect interview techniques risks being denied in court. Research has shown that negative emotions such as sadness and anger can affect the interrogation negatively. The aim of this study was to gain new knowledge about the complexity that child interviewers face

This study explores consumer perceptions of heritage brands following a revolutionary rebrand, with a focus on adapting the Consumer Perceived Value (CPV) theory. Building on Wuestefeld et al.’s (2012) framework, the research incorporates the disruptive nature of revolutionary rebranding to extend the theoretical understanding of CPV in a heritage branding context. Guided by a relativist ontology