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Factors mediating and associated with immunological response in women living with HIV in Sweden : A nationwide register-based study

INTRODUCTION: Women remain underrepresented in studies on immunological response (IR) among virally suppressed people living with HIV. Despite receiving antiretroviral therapy (ART) some individuals do not attain an IR, increasing their risk of non-AIDS morbidity and mortality. This nationwide study investigated biomedical and social factors associated with IR among women with HIV in Sweden.METHOD

Development and validation of multibody road vehicle simulation models for handling studies

Vehicle models are often bound by non-disclosure agreements with manufacturers.This thesis presents a vehicle model based on vehicle data gathered for the NationalAdvanced Driving Simulator in Ohio and therefore it is not bound by such limitationsand can be used in future research projects.The development and validation of the vehicle model requires understanding of thesubsystems studied, componen

Sweden : Swedish society and football at odds with each other – So open, yet so closed

Katarzyna Herd, in this chapter, explores how inequalities and discriminatory practices in Swedish football manifest themselves in a country famous for its liberal and inclusive policies. She recognises that Sweden like most European countries has become a multi-cultural and multi-ethnic society which is clearly reflected in Swedish football. After considering the emergence and (contested) social

β-Cell Function and Glucose Tolerance in Persons With Multiple Islet Autoantibodies Randomized to a Gluten-free Diet

PURPOSE: A randomized clinical trial was conducted to evaluate the impact of a gluten-free diet (GFD) on β-cell function and glucose tolerance in persons with multiple islet autoantibodies.METHODS: Individuals (n = 59; median age 11 years) with multiple islet autoantibodies were recruited to a randomized clinical trial between April 2016 and April 2021. The participants were randomized to a GFD (n

Revising the null model in language evolution research

We comment on the consequences of the target article for language evolution research. We propose that the default assumption should be that of language-readiness in extinct hominins, and the integration of different types of available evidence from multiple disciplines should be used to assess the likely extent of the realization of this readiness. The role of archaeological evidence should be rec

Neutrophil gelatinase-associated lipocalin (NGAL) in lupus nephritis and beyond

Objectives To study neutrophil gelatinase-associated lipocalin (NGAL) levels in peripheral blood in SLE, and to propose a mechanism by which neutrophils secrete NGAL on stimulation with immune complexes (IC). Methods NGAL was measured by ELISA in two independent Swedish SLE cohorts acting as exploratory and validation cohort (n=124 and n=308, respectively), disease controls (n=38) and healthy cont

Isolated digesta as an effective and reliable ex vivo system to study the release profile of drug formulations : study on Candida utilis urate oxidase

Many artificial systems simulate the physiological state of the human gastrointestinal tract (GIT) and its separate compartments. These systems have the biorelevant media and imitate the physical forces and transit times of the GIT compartments, however, they lack the food-related and within-compartmental regulations and thus issues with translation of the data obtained to clinics arise. We aimed

Incompleteness and Not Just Right Experiences in Children and Adolescents with Obsessive-Compulsive Disorder

It is increasingly recognized that feelings of incompleteness and not just right experiences are important emotional and sensory processes underpinning obsessive-compulsive disorder (OCD). Such experiences refer to uncomfortable sensations that something is not right or not in its proper order, and they are typically accompanied by urges to perform behavioral or mental actions until it feels just

Organizational Care Ethics in Times of Geopolitical Crises : A Feminist Perspective

This chapter examines how multinational corporations communicatively navigate moral responsibility during geopolitical crises, focusing on the war in Ukraine. As corporations increasingly are expected to engage with social and political issues, their actions, or inactions, are interpreted as moral stances. We contend that a feminist ethics of care offers a compelling approach through which to unde

Editorial: Special-purpose money for sustainability : Special-purpose money for sustainability

The rationale for this Editorial and the Special Feature Issue (SFI) it introduces is the conviction that money and monetary system design are largely overlooked in debates concerning sustainability. Modern monies (i.e., conventional sovereign fiat currencies) and aspects of them (such as their issuance, functions, and features) tend to be taken for granted as self-evident foundations for the orga

Kalejdoskopisk jazzhistorik

Review of Jan Bruér (2024), Jazz i Sverige – de första hundra åren [Jazz in Sweden – the first hundred years].

Hovslagarns Amanda

En biografi om Amanda Brandt (1833–1915), dotter till en hovslagare och en fattig föräldralös från Västerås, Sverige, som levde ett extraordinärt liv. När hon var sjutton år försökte en av Sveriges mest berömda författare kasta misstankar på henne för en stöld som han själv hade begått. Hon turnerade i Tyskland som sopran och skådespelerska. Vid 27 års ålder fick hon sitt första barn med den världA biography of Amanda Brandt (1833–1915), a farrier’s daughter and a poor orphan from Västerås, Sweden, who led an extraordinary life. When she was seventeen, one of Sweden’s most famous authors tried to cast suspicion on her for a theft he himself had committed. She toured Germany as a soprano singer and actress. At 27, she had her first child with the world-famous African American Shakespearean

A Cross-Sectional Study Demonstrating a High Prevalence of Skin Rash to Diabetes Medical Devices : An Underestimated Problem

Background: Adverse skin reactions to continuous glucose monitors (CGMs) and devices for continuous subcutaneous insulin infusions (CSIIs) (“diabetes medical devices” (MDs)) are well known. However, epidemiological studies on prevalence and skin rash details are lacking. The objective of this study was to describe the prevalence and details of skin rash to diabetes MDs in adults with type 1 diabet

Multi-index method for visualizing robustness of structures

Robustness is the ability of systems to survive unforeseen or unusual circumstances, allowing them to withstand local damage and redistribute stresses to reduce disruptions from component failures. It may be measured by calculating the probability of system failure when specific components fail, compared to the overall system reliability. However, treating robustness and reliability as opposites c

Pain in adults with cerebral palsy : A systematic review

Aim: To describe the prevalence and incidence of pain, identify prognostic factors for pain, determine psychometric properties of tools to assess pain, and evaluate effectiveness of interventions for reducing pain among adults with cerebral palsy (CP). Method: Six databases were searched to identify studies published since 1990 in any language that met eligibility criteria defined for each objecti

Amyloid-β deposition predicts oscillatory slowing of magnetoencephalography signals and a reduction of functional connectivity over time in cognitively unimpaired adults

With the ongoing developments in the field of anti-amyloid therapy for Alzheimer’s disease, it is crucial to better understand the longitudinal associations between amyloid-β deposition and altered network activity in the living human brain. We included 110 cognitively unimpaired individuals (67.9 ± 5.7 years), who underwent [18F]flutemetamol (amyloid-β)-PET imaging and resting-state magnetoenceph