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The purpose of this study is to explore the inclusive involvement of non-R&D and non-managerial employees’ in processes of innovation. It answers a contemporary call for research to investigate a wider scope of organisations in the quest for understanding the interaction between employees and managers in employee-driven innovation (EDI). Based on a qualitative research study of two global corp
Multifunctional, light-weight, responsive materials show promise in a range of applications including soft robotics, therapeutic delivery, advanced diagnostics and charge storage. This paper presents a novel, scalable, efficient and sustainable approach for the preparation of cellulose nanofibril-based aerogels via a facile ice-templating, solvent exchange and air-drying procedure, which could rep
Poly(3-hexylthiophene) (P3HT) is found to be a highly effective conductivity-reducing additive for low-density polyethylene (LDPE), which introduces a new application area to the field of conjugated polymers. Additives that reduce the direct-current (DC) electrical conductivity of an insulation material at high electric fields have gained a lot of research interest because they may facilitate the
This article investigates how Nordic and American Lutherans reached an understanding over the formation of a future World Council of Churches. During the inter-war period different attitudes towards a nascent ecumenical movement developed on each side of the Atlantic. With an increasing recognition of the need to develop inter-Christian co-operative bodies, leading Nordic Lutherans tended not to f
Objectives: Absence of a functional interferon-λ 4 (IFN-λ4) gene (IFNL4) predicts spontaneous resolution of acute hepatitis C virus (HCV) infections in regions with a predominance of genotype 1, whereas variants of the inosine triphosphate pyrophosphatase (ITPase) gene (ITPA) entailing reduced activity associate with increased sustained virologic response rates following some therapeutic regimens.
Purpose: Bilateral adrenalectomy (BA) still plays an important role in the management of Cushing's disease (CD). Nelson’s syndrome (NS) is a severe complication of BA, but conflicting data on its prevalence and predicting factors have been reported. The aim of this study was to determine the prevalence of NS, and identify factors associated with its development. Data sources: Systematic literature
Aim: Statins lower cholesterol and reduce the risk of cardiovascular disease. However, the exact mechanisms of statins remain unknown. We investigated whether statin therapy associates with epigenetics in Type 2 diabetes (T2D) patients. Materials & methods: DNA methylation was analyzed in blood from newly diagnosed T2D patients in All New Diabetics in Scania (ANDIS) and a replication cohort Al
Enterohemorrhagic Escherichia coli secrete Shiga toxin and lead to hemolytic uremic syn-drome. Patients have high levels of circulating prothrombotic extracellular vesicles (EVs) that expose phosphatidylserine and tissue factor and transfer Shiga toxin from the circulation into the kidney. Annexin A5 (AnxA5) binds to phosphatidylserine, affecting membrane dynamics. This study investi-gated the eff
The fast-growing market of electric bikes (e-bikes) has introduced a paradigm shift in mobility with a promise to enhance the sustainability agenda. An in-depth understanding of transport quality of service (QOS) from the e-bike rider’s perspective is a promising approach to sustain the role of the e-bike in mobility. Level of service (LOS) is a method by which to quantify QOS for different transp
BACKGROUND: Mucinous cystadenocarcinomas (MCAC) of the pancreas are rare tumors. When localized to the pancreas alone, surgical resection is mostly associated with a favorable prognosis. The potential value of palliative treatment with chemotherapy for irresectable disease is scarcely described though. The aim of this study was to describe a single-center series of patients with MCAC of the pancre
Although CD8+ T cell tolerance to tissue-specific antigen (TSA) is essential for host homeostasis, the mechanisms underlying peripheral cross-tolerance and whether they may differ between tissue sites remain to be fully elucidated. Here, we demonstrate that peripheral cross-tolerance to intestinal epithelial cell (IEC)–derived antigen involves the generation and suppressive function of FoxP3+CD8+
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In this explorative paper, we examine the emerging body of scholarship that has recently started incorporating more-than-human perspectives in the nexus of law, society, and animals. While ‘more-than-human’ refers to a plurality of theoretical positions, for our purpose we take these positions to reflect the attempt to move away from human exceptionalism in favour of a multispecies account of the
ABSTRACTINTRODUCTION Globally, 20% of women who become pregnant are obese at the time of conception. The prevalence of women becoming pregnant after gastric bypass (GBP) surgery has been increasing. Little is known regarding women’s experiences of pregnancy after GBP surgery and midwives can expect to care for an increasing number of women with prior GBP surgery. Midwives play an important role in
In Zimbabwe common mental disorders are prevalent among adolescents and the treatment gap is large. The recently introduced Youth Friendship Bench intervention (YouFB) addresses this gap by task-shifting youth lay health workers to offer a culturally contextualised, manual-based, six-session problem-solving therapy to adolescents, 16-19 years of age. The aim of this study was to explore participanIn Zimbabwe common mental disorders are prevalent among adolescents and the treatment gap is large. The recently introduced Youth Friendship Bench intervention (YouFB) addresses this gap by task-shifting youth lay health workers to offer a culturally contextualised, manual-based, six-session problem-solving therapy to adolescents, 16-19 years of age. The aim of this study was to explore participan
In an attempt to summarize and draw preliminary conclusions from the many fine responses to my article ‘Stop evaluating science’, this short piece brings some additional reflections on the topic with the primary intent not to close the debate but to keep it open. Discussing, in turn, three main topics of the responses and an additional topic that arguably is of particular interest, the article’s i
