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A multi-scaling approach showing a transient metabolic mismatch in a freshwater fish (Zingel asper) during an acute heat stress

Heat stress events will be more frequent and intense in the future. These events will challenge the capacity of organisms to exhibit sufficient metabolic flexibility to adapt to such variations. To better understand the acclimation processes implemented in response to acute warming, with an integrative approach we examined in vivo metabolic rate and cardiac mitochondrial respiration in the Rhône s

Integrative taxonomy, phylogeny and distribution patterns of the diverse Neotropical cloud forest butterfly genus Perisama Doubleday (Nymphalidae, Biblidinae, Callicorini)

Phylogenetic relationships of the predominantly Andean species-rich nymphalid genus Perisama are explored based on five genetic markers and a total of 3719 bps, and morphological characters of the adults with an emphasis on male genitalia and wing colour patterns. Its monophyly is recovered by including the genera Orophila, which turns out polyphyletic, and Mesotaenia. Two main, highly supported c

Persistent increase of Nogo-A-positive cells and dynamic reduction in oligodendroglia lineage cells in white matter regions following experimental and clinical traumatic brain injury

White matter (WM) disruption and atrophy is a consequence of traumatic brain injury (TBI) and contributes to persisting cognitive impairment. An increased expression of the myelin-associated axonal outgrowth inhibitor Nogo-A and oligodendrocyte pathology might be negatively associated with postinjury WM changes. Here, we analyzed brain tissue from severe TBI patients, obtained by surgical decompre

Bilayer orthogonal ferromagnetism in CrTe2-based van der Waals system

Systems with pronounced spin anisotropy are pivotal in advancing magnetization switching and spin-wave generation mechanisms that are fundamental to spintronic technologies. Quasi-van der Waals ferromagnets like Cr1+δTe2 represent seminal materials in this field, renowned for their delicate balance between frustrated layered geometries and magnetism. Despite extensive investigation, the nature of

Characterization of Portable Ultra-Low Field MRI Scanners for Multi-Center Structural Neuroimaging

The lower infrastructure requirements of portable ultra-low field MRI (ULF-MRI) systems have enabled their use in diverse settings such as intensive care units and remote medical facilities. The UNITY Project is an international neuroimaging network harnessing this technology, deploying portable ULF-MRI systems globally to expand access to MRI for studies into brain development. Given the wide ran

Charge carrier dynamics controlling performance of lead-based halide perovskite solar cells

We review our studies to assess charge carrier dynamics inside a perovskite film and interfacial charge transfer dynamics for a perovskite layer sandwiched by an electron transporting layer (ETL) such as TiO2 compact or mesoporous layer and a hole transporting layer (HTL) such as spiro-OMeTAD. Both electron and hole injection occur faster than electron-hole recombination inside a perovskite film,

Gene expression-based identification of prognostic markers in lung adenocarcinoma

Introduction Many studies have aimed at identifying additional prognostic tools to guide treatment choices and patient surveillance in lung cancer by assessing the expression of individual proteins through immunohistochemistry (IHC) or, more recently, through gene expression-based signatures. As a proof-of-concept, we used a multi-cohort, gene expression-based discovery and validation strategy to

Illuminating the Invisible: Green Fluorescent Protein as a Beacon for Antibiotic-Induced Phage Activity in Escherichia coli.

Background/Objectives: Antibiotic resistance presents an urgent public health threat. By developing a streamlined and effective method for studying bacteriophage induction, this research marks a step further in understanding how antibiotic-resistant genes might spread across different environments. This knowledge is essential for creating strategies to reduce the spread of antimicrobial resistanc

Impact of different carbon labels on consumer inference

Carbon labelling of food products serves as a demand-side tool with the potential to drive the essential shift in consumption patterns toward reducing climate impact. For carbon labels to influence food choices, they must enable consumers to recognize and adopt purchasing behaviour that lower their climate footprint. While inference plays a critical role in facilitating behavioural change, evidenc

Using SILMAS to improve machine learning-assisted quantification of pathology

In this study, we investigate the benefits of using structured illumination light-sheet microscopy with axial sweeping (SILMAS) in the context of neural network-assisted quantification of pathology in volumetric data. A bottleneck for training a neural network is the availability of manually labeled training data that adequately covers the variance in unseen samples, allowing the network to correc

Tourism satellite account for Sweden 1992-93

This paper calculates the consumption expenditure of internal visitors in Sweden, and Swedes' expenditures on outboard tourism, according to the WTO definition of tourism expenditure. The demand-based calculations of national tourism are distributed among same-day visitors and overnight visitors, for leisure and business purposes. The supply side calculations cover the main tourism industries. Dai

A new approach to modelling and forecasting monthly guest nights in hotels

Starting from a day-to-day model on hotel specific guest nights we obtain an integer-valued moving average model by cross-sectional and temporal aggregation. The two parameters of the aggregate model reflect mean check-in and the check-out probability. Letting the parameters be functions of dummy and economic variables we demonstrate the potential of the approach in terms of interesting interpreta

Enhancing Photothermal Therapy Against Breast Cancer Cells by Modulating the End Point of Gold Shell-Isolated Nanoparticles Using Nanostraw-Assisted Injection

Gold shell-isolated nanoparticles (AuSHINs) are promising photothermal therapy (PTT) agents for cancer treatment due to their excellent photoconversion efficiency, biocompatibility, colloidal stability, and tunable properties, including size, shape, and surface functionalization. However, their therapeutic efficacy in in vitro assays is often limited by poor cellular uptake and lysosomal entrapmen