Undersökning av en ny metod att söka efter inhibitorer Vad görs när immunsystemet, systemet byggt för att skydda oss, attackerar oss istället? I dagsläget finns inte så mycket man kan göra. Jag har därför undersökt en ny metod för att hitta ämnen som ska kunna hindra det trasiga immunsystemet från att skada! Framsteg inom medicinen är bland de viktigaste som kan göras för mänsklighetens fortlevnaThe main purpose of this master thesis was to test a novel approach of finding leads for new pharmaceuticals, by using Solid Phase Peptide Synthesis (SPPS) in combination with Weak Affinity Chromatography (WAC). Put in a more concrete way, the objective was to find a lead for a better human neutrophil elastase inhibitor. The plan was to take advantage of the fact that the tripeptide Valine-Proline

Detta examensarbete behandlar frågan kring vilken påverkan som idrottsarenor har på fastighetsvärden. Studien grundas i de stora arenaprojekt som har genomförts i Sverige under de senaste åren. Bara i Stockholmsområdet har två stora idrottsarenor byggts och en stor idrottsarena rivits. Projekt som dessa är väldigt kapitalkrävande varpå det är viktigt för de inblandade i projekten att ta reda på vaThis master thesis addresses the issue of the impact of sports arenas on real estate values. The study is based on the major stadium projects that have been implemented in Sweden in recent years. Only in the Stockholm area have two major sports stadiums been built and one major sports stadium have been demolished. Projects like these are very kapital-intensive, so it is important for those involve

Conservation Voltage Reduction, or short just CVR, is a technique in which the reference voltage at a substation is lowered a few percent in order to conserve energy and decrease peak demand in an electrical distribution grid. Thus, CVR can be used when the energy or power capacity can't be satisfied by the feeding grid. Energy capacity has been a recurring topic in Sweden for a long time with

Communication in aquatic habitats commonly occurs via chemicals released from organisms. Chemical cues are used to detect prey and predators, and hence, play an important role in predator-prey interactions. Chemical cues from predators may induce morphological and behavioural responses in prey. For example, crucian carp (Carassius carassius) has demonstrated a morphologically induced defence with

In 2018, the Swedish government decided to invest 350 million SEK in welfare technology as a response to the increasing population of the elderly. The aim of this study was to investigate implementation managers’ descriptions of their work and use of welfare technology. The interviews were conducted at three long-term facilities for the elderly in the municipality of Burlöv, Helsingborg, and Hässl

Dataskyddsförordningen, GDPR, ämnar att skydda personuppgifter genom att sätta den registrerades intressen är i fokus, samtidigt som lagen specifikt beaktar mikro-företag samt små och medelstora företags, SMEs, särskilda behov. Uppsatsen närmar sig denna problematik från ett perspektiv baserat på grundläggande rättigheter; problemformuleringen är hur mindre företags rättigheter och intressen kan bThe General Data Protection Regulation, GDPR, aims to provide protection of personal data which is centred on the data-subject, while at the same time categorically giving special consideration to the specific needs of micro, small and medium‑sized enterprises, SMEs. The paper approaches this conundrum from a fundamental rights angle, and tries to answer how the rights and interests of smaller bus

The investigation of children's and young people’s need for protection and safety is carried out by social services and is regulated by Socialtjänstlagen chapter 1, § 2. In a case where a child is granted outpatient care, the necessity of follow-ups to ensure that progress is being made is specified in the law. The law does not however define the frequency of these follow-ups. The aim was ther

2016 tillsatte regeringen en utredning för att undersöka regleringen av den villkorliga frigivningen. Utredningen fick i uppdrag att undersöka om det finns skäl att föregå ett beslut om uppskjuten villkorlig frigivning med en riskbedömning av huruvida det finns risk för klienter i kriminalvårdsanstalt att återfalla i brott vid frigivningen. Utredningen kom fram till att det strider mot kravet på rIn 2016, the government commissioned an investigation to consider possible changes in the regulation of the conditional release. The investigation was commissioned to investigate whether there is a reason to precede a decision on a deferred conditional release with a risk assessment of whether there is a risk for clients in prison to re-offend when released. The investigation found that allowing p

Abstrakt Introduktion: Psykisk ohälsa är ett växande problem i dagens samhälle. Personer som är drabbade hamnar inte sällan i social isolering, svårigheter att bibehålla arbete och/eller relationer med andra människor. Sedvanlig behandling består till största delen av medicinsk behandling, ECT och samtal. Drama kan vara en kompletterande metod att behandla individer som upplever svårigheter i att

Today, in a digital era where people can do their everyday tasks from home, the city as a social platform faces new challenges. Individuals no longer need to run errands around the city, which, until now, has been the standard way of city life. The comfort of today’s modern world impacts not only the private but also the public life of cities. The urban dynamics of city life are likely to be reduc

A fundamental component of episodic memories, allowing for their vividness and detail in recollection, is the visual context accompanying it. At times, it has been found that such memories may bind with one another. In such memory integration, the visual context accompanying the integrated events, may been found to be a key component. Yet, though the importance of context on episodic memories has

Det ökade användandet av träbaserade volymelement i flerfamiljshus kräver effektiva och detaljerade beräkningsmetoder. Numeriska modeller av volymelementen ger stora fördelar med avseende på analys av stabilitet mot vindlaster genom möjligheten att beakta hela den tredimensionella konstruktionens styvhet.The use of timber volume elements (TVEs) in residential multi-storey buildings is increasing in popularity. Manufacturing methods and building processes have been streamlined to improve product quality. However, further streamlining still remains concerning the efficiency of current calculation methods, as many developers still use simple hand calculations. The objective with this dissertation was

The present thesis is an investigation about the analysis and study of what is the best way to obtain greater savings of heat principally from the reuse of Drain Hot Water (DWH). The study is carried out through the hypothetical application of one of these heat reuse systems and the installation of renewable solar system to reduce the electricity consume in a single-family house of 300 m2 located

This paper investigates the relationship between financial performance and sustainable performance. More specifically, it investigates whether sustainable firms outperform less sustainable firms. The sustainable performance is based on companies received ESG score. The ESG rating system is based on three equally weighted pillars, environmental, social and governance. The study is based on stocks i

Normalisering av en byggnads energianvändning med avseende på verksamhetstypen (brukarnas energibruk) och klimat genomförs för att byggnadens energiprestanda ska vara jämförbar med andra byggnader samt för att verifiera att ställda energikrav uppfylls. Metoder för normalisering utarbetades som följd av införandet av Europaparlamentets och rådets direktiv 2010/31/EU av den 19 maj 2010 om byggnaders

We present an experimental investigation of the dynamics of near-to-sphere colloidal ellipsoids in which we deploy a recently developed technique differential dynamic microscopy (DDM). Inherently opaque systems as well as progressively dense dispersions exhibit multiple scattering and as conventional techniques such as dynamic light scattering (DLS) suffer from this effect, studies probing their d

Att vårt klimat är i förändring och att valen vi gör måste förändras blir allt mer påtagligt. Våra transportsystem är i omställning mot mer förnybara drivmedel och ett val som många idag gör är att skaffa sig en elbil. Elbilarna behöver framförallt kunna laddas från elnätet vid förarens bostad, där bilen oftast står parkerad under natten. Olika typer av laddstationer uppförs därför i bostadsmiljöeThe development of the transportation system is transitioning to use renewable fuels and in Sweden, many people are now choosing to buy electric cars. Primarily, the electric cars need to charge from the electric grid, usually at the driver’s residence, where the car is parked during the night. Different types of charging stations are thereby built in residential areas. Problems usually do not occ

Understanding material behaviour has in the past enabled human development and will continue to characterize the various stages of our future development. The use of neutrons will greatly affect several research areas, such as sustainable energy production and cancer research, due to their interaction with nuclei. Neutrons will thus interact differently depending on the specific isotope, reveal in