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Preparation of stable radioiodinated polypeptide hormones and proteins using polyacrylamide gel electrophoresis

This chapter discusses the preparation of stable radioiodinated polypeptide hormones and proteins using polyacrylamide gel electrophoresis. Radioactively labeled polypeptide hormones and proteins are widely used as tracers in radioimmunoassays and receptor studies. The peptide or protein is most easily labeled using iodination with 125I or 131I. The radioactive iodine is substituted in the tyrosin

Motor Imagery to Facilitate Sensorimotor Re-Learning (MOTIFS) after traumatic knee injury: : study protocol for an adaptive randomized controlled trial

BackgroundTreatment following traumatic knee injury includes neuromuscular training, with or without surgical reconstruction. The aim of rehabilitation is to restore muscle function and address psychological factors to allow a return to activity. Attention is often on rehabilitation of knee function, but deficiencies often persist. Specific interventions addressing psychological factors are sparin

Analysis of policy frameworks for ‘children in care’ in Sweden

In a joint South African and Swedish research study, policy frameworks for children in care were analysed in regard to children’s rights and accessibility to participate in decisions on care. The research group has during phase one in the study developed a series of questions to analyse the most relevant legislations in regard to children in care. Thus, for the Swedish part of the analysis four le

Distinct Molecular Signatures of Clinical Clusters in People with Type 2 Diabetes : an IMIRHAPSODY Study

Type 2 diabetes is a multifactorial disease with multiple underlying aetiologies. To address this heterogeneity a previous study clustered people with diabetes into five diabetes subtypes. The aim of the current study is to investigate the aetiology of these clusters by comparing their molecular signatures. In three independent cohorts, in total 15,940 individuals were clustered based on five clin

School-based hearing screening in Sweden – An evaluation of current practices

Objectives: Routines for school hearing screening vary between municipalities in Sweden, and no study has been carried out to investigate how this is conducted throughout the country. The aim of the present study was to determine the extent of school hearing screening, and how it is performed in all the municipalities in Sweden. Methods: An online survey was used to collect information on school h

Physical impairments in longstanding hip and groin pain : Cross-sectional comparison of patients with hip-related pain or non-hip-related groin pain and healthy controls

Objectives: To compare physical impairments between patients with hip-related pain and those with non-hip-related groin pain, and to compare both patient groups with healthy controls. Design: Cross-sectional. Participants: Eighty-one hip and groin pain patients were consecutively included and categorized into having hip-related pain or non-hip-related groin pain. Twenty-eight healthy controls were

Compensating for a stressful pregnancy? Glucocorticoid treatment during gravidity reduces metabolic rate in female fence lizards post-parturition

Reproduction is a critical part of an animal's life history, but one which incurs significant costs to survival and future reproductive potential. These physiological consequences are likely to be influenced by context – for example, if an individual is subject to environmental stressors, physiological and behavioral changes associated with reproduction may be altered. Glucocorticoids, hormones pr

Blood culture time to positivity in non-β-hemolytic streptococcal bacteremia as a predictor of infective endocarditis-a retrospective cohort study

Non-β-hemolytic streptococci (NBHS) cause infective endocarditis (IE) and a short blood culture time to positivity (TTP) is associated with risk of IE in bacteremia with other pathogens. In this retrospective population-based cohort study, we investigate if TTP is associated to IE or mortality. Of 263 episodes with NBHS bacteremia, 28 represented IE and the median TTP did not differ significantly

Ombordmätningar av partiklar och koldioxid i X60B förarhytter

SyfteMålsättningen med denna studie var dels att säkerställa att tågpersonalen inte utsätts för höga halter av partiklar i sitt arbete på X60B fordon som trafikerar Arlanda. Syftet var även att ta fram ett förhållande mellan partikelnivåerna i tunnelmiljö och ombord på pendeltågsfordon av typ X60B i förarhytterna för att avgöra ventilationsfiltrets kapacitet. Kunskapen om filtreringseffektiviteten

Ranking of conventional and novel disc brake materials with respect to airborne particle emissions

PM10 from the wear of disc brakes could contribute up to 50 % of the total non-exhaust emissions from road transport in EU. The wear originates from the contact surfaces of the friction material and the disc. One possible way of decreasing the PM10 emissions is to change the materials of the contact pair in terms of composition and coatings. Therefore the particle emissions of three novel friction

Eco Design of Brake Pads with Recycled Friction Materials

Recycling of brake pads is a tough but promising work considering the current end of lifecycle. This study assesses the environmental performance of brake pads made up of recycled friction materials in terms of energy use, CO2 footprint and airborne particle number. Energy use and CO2 footprint are calculated with the data from CES Edupack and airborne emission particle number is measured on a pin

Utsådda blommor räddar inte insekterna

Om vi vill rädda hotade insekts­arter är det miljöer med traditionella ängs­växter som vi behöver mer av, inte frö­blandningar av oklart ursprung från handeln. Det skriver flera debattörer.

Revisiting Optical Reflectance from Au(111) Electrode Surfaces with Combined High-Energy Surface X-ray Diffraction

We have combined high-energy surface X-ray diffraction (HESXRD) with 2D surface optical reflectance (2D-SOR) to perform in situ electrochemical measurements of a Au(111) electrode in 0.1 M HClO4 electrolyte. We show that electrochemically induced changes to Au(111) surface during cyclic voltammetry can be simultaneously observed with 2D-SOR and HESXRD. We discuss how small one atom high 1x1 island

The contributions of public health policies and healthcare quality to gender gap and country differences in life expectancy in the UK

Background: In many high-income countries, life expectancy (LE) has increased, with women outliving men. This gender gap in LE (GGLE) has been explained with biological factors, healthy behaviours, health status, and sociodemographic characteristics, but little attention has been paid to the role of public health policies that include/affect these factors. This study aimed to assess the contributi