Comparison of serum levels of inflammatory marker Calprotectin, indicating intestinal inflammation, in patients with Sjögren´s syndrome versus patients with IBD, and detection of autoreactive T cells
Sjögren’s syndrome (SS) is a chronic autoimmune disease with exocrine glands dysfunction and multi organ involvement. Sicca symptoms such as xerophthalmia and xerostomia are the most common features in this disease. Increased intestinal permeability has been demonstrated in various autoimmune disorders, and Calprotectin, a protein released by neutrophils and monocytes due to cell stress or damage,