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Background. Myocardial infarction (MI) remains the leading cause of death worldwide, despite several advances in acute coronary care during the last decades. This thesis assessed different risk stratification tools and evaluated interventional and pharmacological treatment strategies in high-risk patients with MI. Methods. This work comprises four studies. The first and the fourth study extracted
Biofuels from vegetable oils or animal fats are considered to be more sustainable than petroleum-derived diesel fuel. In this study, we have assessed the effect of hydrogenated vegetable oil (HVO) exhaust on levels of DNA damage in peripheral blood mononuclear cells (PBMCs) as primary outcome, and oxidative stress and inflammation as mediators of genotoxicity. In a randomized cross-over study, hea
We show that a recent spectral flow approach proposed by Berkolaiko–Cox–Marzuola for analyzing the nodal deficiency of the nodal partition associated to an eigenfunction can be extended to more general partitions. To be more precise, we work with spectral equipartitions that satisfy a pair compatible condition. Nodal partitions and spectral minimal partitions are examples of such partitions. Along
Background and purpose: Up-to-date population-based information about long-term survival, causes of death and recurrence after stroke is needed. Methods: Four hundred consecutive individuals in a population-based cohort of first-ever stroke between 2015 and 2016 in Lund, Sweden, were followed up to 3 years regarding (i) survival (Swedish Population Register); (ii) causes of death (Swedish Causes o
Background: The SIOP-Renal Tumor Study Group (RTSG) does not advocate invasive procedures to determine histology before the start of therapy. This may induce misdiagnosis-based treatment initiation, but only for a relatively small percentage of approximately 10% of non-Wilms tumors (non-WTs). MRI could be useful for reducing misdiagnosis, but there is no global consensus on differentiating charact
Academia, as many other sectors, has faced wide-ranging disruptions due to COVID-19, with teaching and research activity conducted entirely online in many countries. Before the pandemic grounded travel, academics were often hypermobile, some traveling more than 150,000 kilometers per year for conferences, board meetings, collaborations, fieldwork,seminars, and lectures. It is no surprise then that
This paper discusses methods to test the performance of the adaptation layer in a self-adaptive system. The problem is notoriously hard, due to the high degree of uncertainty and variability inherent in an adaptive software application. In particular, providing any type of formal guarantee for this problem is extremely difficult. In this paper we propose the use of a rigorous probabilistic approac
Objective: To assess which structural abnormalities on knee MRI are associated with development of osteophytes in middle-aged subjects without radiographic knee osteoarthritis. Design: We included subjects from the Osteoarthritis Initiative, aged 40–55 years, Kellgren & Lawrence grade 0 in both knees, and knee MRIs from both knees available at baseline, 24, 48 and 72 months. Structural exposur
The high cycle fatigue behaviour of autoclave-cured carbon fibre-reinforced polymer (CFRP) composite gears is investigated. The CFRP gears were milled from a composite plate and tested in mesh with a steel drive gear under five torque loads ranging between 0.4 and 0.8 Nm in unlubricated conditions. A detailed gear damage analysis is conducted by employing scanning electron microscopy and high-reso
This special issue follows on from a special call for contributions tothe ECER 2016 conference in Dublin on the need to rethink andreconceptualise internationalisation in higher education (HE). Thepapers in this special issue contribute to a critically reflectiveinterdisciplinary discussion on the phenomena ofinternationalisation in terms of the evolution of the structures,systems, and functions o
The purpose of this thesis is to add an astronomical component to the history and evolution of Earth by reconstructing the micrometeorite flux to Earth at different time intervals during the Phanerozoic Eon, using sediment-dispersed extraterrestrial spinel group minerals as a proxy. Chromite and chrome spinel are common refractory members of the spinel group, occurring in both extraterrestrial and
Introduction: Antimicrobial resistance (AMR) is a global public health threat. Worse still, there is a paucity of data from low-and middle-income countries to inform rational antibiotic use. Objective: Assess the feasibility of setting up microbiology capacity for AMR testing and estimate the cost of setting up microbiology testing capacity at rural district hospitals in Rwanda. Methods: Laborator
Background: Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anoma
Sweden is actively seeking to scale up repair activities as part of its strategy to reduce waste, transition to a circular economy, and achieve zero net emissions by 2045. In the last couple of years, several new policies to promote consumer repairs have been adopted or proposed in Sweden. However, very little is known about the socio-cultural factors that shape people's decision to repair their p
