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The protein product of the deleted in colorectal cancer (DCC) gene possesses netrin-binding activity and may be involved in axonal guidance during retinal development. The temporal and spatial expression of DCC was analyzed in developing rat retina by means of immunoblotting and immunohistochemistry as well as by reverse transcription-polymerase chain reaction. Transient DCC protein expression is
Acetylcholine is well established as the neurotransmitter of starburst amacrine cells in the vertebrate retina but their function is poorly understood. We compared the distribution of muscarinic m2 receptors in the rat retina with the localization of the starburst cell processes. mAChR2 immunoreactivity appeared in a central band in the inner plexiform layer, which did not co-localize with the pro
The goal of this paper is to investigate whether multiple correspondence analysis (MCA), a multivariate statistical technique, is a useful dimensionality-reduction tool in zooarchaeological and taphonomic studies. For this purpose, the focus is to detect and discuss traces of waste management. Animal bones from waste-related contexts at the Bronze Age site Asine, Greece, are investigated. The data
The actor’s practice and bodily training during the twentieth century are specifically related not only to different bodily techniques, but also to language, modern society, and the concept of freedom. Nationalism, anti-intellectualism, bodily and vitalistic purism, and a sceptical distance from the modern project at the beginning of the twentieth century serve as a starting point for a discussionThe actor’s practice and bodily training during the twentieth century are specifically related not only to different bodily techniques, but also to language, modern society, and the concept of freedom. Nationalism, anti-intellectualism, bodily and vitalistic purism, and a sceptical distance from the modern project at the beginning of the twentieth century serve as a starting point for a discussion
In this paper, we describe Langforia, a multilingual processing pipeline to annotate texts with multiple layers: formatting, parts of speech, named entities, dependencies, semantic roles, and entity links. Langforia works as a web service, where the server hosts the language processing components and the client, the input and result visualization. To annotate a text or a Wikipedia page, the user c
In this paper, we investigate the annotation projection of semantic units in a practical setting. Previous approaches have focused on using parallel corpora for semantic transfer. We evaluate an alternative approach using loosely parallel corpora that does not require the corpora to be exact translations of each other. We developed a method that transfers semantic annotations from one language to
In this paper, I describe systems and prototypes we created in the natural language processing group at Lund to extract structured knowledge from text. Starting from syntactic and semantic parsingcomponents,wedevelopedapplicationsthatcanhandlelargecorpora,typicallycomplete Wikipedia versions consisting of millions of documents and process text to identify entities and the relations between them. I
We present a survey of the radiation background at the Spallation Neutron Source (SNS) at Oak Ridge National Laboratory, TN, USA during routine daily operation. A broad range of detectors was used to characterize primarily the neutron and photon fields throughout the facility. These include a WENDI-2 extended range dosimeter, a thermoscientific NRD, an Arktis 4He detector, and a standard NaI photo
Xylooligosaccharides (XOS) have gained increased interest as prebiotics during the last years. XOS and arabinoxylooligosaccharides (AXOS) can be produced from major fractions of biomass including agricultural by-products and other low cost raw materials. Endo-xylanases are key enzymes for the production of (A)XOS from xylan. As the xylan structure is broadly diverse due to different substitutions,
The thermostable β-glucosidase from Thermotoga neapolitana, TnBgl3B, is a monomeric three-domain representative from glycoside hydrolase family 3. By using chemical reactivation with exogenous nucleophiles in previous studies with TnBg13B, the catalytic nucleophile (D242) and corresponding acid/base residue (E458) were determined. Identifying these residues led to the attempt of converting TnBgl3B
Decision making and requirements scoping occupy central roles in helping to develop products that are demanded by the customers and ensuring company strategies are accurately realized in product scope. Many companies experience continuous and frequent scope changes and fluctuations but struggle to measure the phenomena and correlate the measurement to the quality of the requirements process. We pr
Oligodendrocyte (OL) death may contribute to white matter pathology, a common cause of network dysfunction and persistent cognitive problems in patients with traumatic brain injury (TBI). Oligodendrocyte progenitor cells (OPCs) persist throughout the adult CNS and may replace dead OLs. OL death and OPCs were analyzed by immunohistochemistry of human brain tissue samples, surgically removed due to
Eating disorders (EDs) are common and serious psychiatric disorders causing significant physical and psychological suffering, for both those afflicted and their significant others. Although there has been considerable research on EDs throughout the years, there is still much left to be desired for successful treatment.Perfectionism has been suggested to play a crucial role in the development and m
Rubinstein–Taybi syndrome (RSTS) is a developmental disorder characterized by a typical face and distal limbs abnormalities, intellectual disability, and a vast number of other features. Two genes are known to cause RSTS, CREBBP in 60% and EP300 in 8–10% of clinically diagnosed cases. Both paralogs act in chromatin remodeling and encode for transcriptional co-activators interacting with >400 prote
Background:Much of the current literature on diet-colorectal cancer (CRC) associations focused on studies of single foods/nutrients, whereas less is known about nutrient patterns. We investigated the association between major nutrient patterns and CRC risk in participants of the European Prospective Investigation into Cancer and Nutrition (EPIC) study.Methods:Among 477 312 participants, intakes of
Since the 1990s, the low number of students choosing to study science and technology in higher education has been on the societal agenda and many initiatives have been launched to promote awareness regarding career options. The initiatives particularly focus on increasing enrolment in the engineering programmes. This article describes and compares eight European initiatives that have been establis
