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Higher glutamate and glutamine (together: Glx) and lower N-acetyl-aspartate (NAA) levels were reported in schizophrenia. Endurance training normalizes NAA in the hippocampus, but its effects on other metabolites in the brain and the relationship of metabolites to clinical symptoms remain unknown. For 12 weeks, 20 schizophrenia inpatients (14 men, 6 women) and 23 healthy controls (16 men, 7 women)
Objectives: To investigate dogs with acute onset of intracranial signs suspected of stroke by primary veterinary clinicians, and establish possible differential diagnoses and long-term outcome. In addition, serum C-reactive protein and plasma cytokines were investigated as potential biomarkers of disease. Materials and Methods: All cases were evaluated by neurologic examination, routine haematolog
SUGCT (C7orf10) is a mitochondrial enzyme that synthesizes glutaryl-CoA from glutarate in tryptophan and lysine catabolism, but it has not been studied in vivo. Although mutations in Sugct lead to Glutaric Aciduria Type 3 disease in humans, patients remain largely asymptomatic despite high levels of glutarate in the urine. To study the disease mechanism, we generated SugctKO mice and uncovered imb
Chemokines are important in the development and progression of tumors. We investigated the expression of CXCL14 and CXCL16 in colon cancer. Expression of mRNA was assessed in primary tumors and lymph nodes and CXCL16 mRNA levels were correlated to patient’s survival. Protein expression was investigated by two-color immunofluorescence and immunomorphometry. CXCL14 and CXCL16 mRNA levels and protein
Importance: Breast cancer screening guidelines acknowledge the need for earlier screening for women at increased risk but provide limited guidance for women with a family history of breast cancer. A risk-adapted starting age of screening for relatives of patients with breast cancer may help supplement current screening guidelines. Objective: To identify the risk-adapted starting age of breast canc
This chapter presents my analytical journey from conviviality, a concept used for analysing diversity in Istanbul to overcome the pitfalls of multiculturalism and coexistence theories, to the development of the concept of convivial solidarity for the analysis of transnational civil society organisations that support refugees and migrants in Denmark. Convivial solidarity is my construct and I use i
We present a generalisation of the flavour-ordering method applied to the chiral nonlinear sigma model with any number of flavours. We use an extended Lagrangian with terms containing any number of derivatives, organised in a power-counting hierarchy. The method allows diagrammatic computations at tree-level with any number of legs at any order in the power-counting. Using an automated implementat
Hybridization is a natural process at species range boundaries, but increasing numbers of species are hybridizing due to direct or indirect human activities. In such cases of anthropogenic hybridization, subsequent introgression can threaten the survival of native species. To date, many such systems have been studied with too few genetic markers to assess the level of threat resulting from advance
In this work, the possibility of using planar droplet sizing (PDS) based on laser-induced fluorescence (LIF) and Mie scattering was investigated within the framework of measuring the droplet Sauter mean diameter (SMD) of direct-injection spark-ignition (DISI) spray systems. For this purpose, LIF and Mie signals of monodisperse fuel droplets produced by a droplet generator were studied at engine re
Root-induced channels are the primary controlling factors for rapid movement of water and solute in forest soils. To explore the effects of root distribution on preferential flow during rainfall events, deciduous (Quercus variabilis BI.) and coniferous forest (Platycladus orientalis (L.) Franco) sites were selected to conduct dual-tracer experiments (Brilliant Blue FCF and Bromide [Br-]). Each plo
Concerns have been raised about the potential adverse effects of liberalizing trade in services under the GATS framework on equity, costs, distribution, availability of services and sovereignty of governments in defining their national objectives. These concerns have been voiced in poor countries in case of such social service sectors as health and education. Critics have stressed the need for an
Based on a comparative study of the social economic development and the water resources characteristics in 13 arid inland basins of north-western China, it is pointed out that oasis will move from lower reach to upper reach in the circumstances of lower water availability per capita and poorer social economic structures. A significant ecological warning line and warning interval of oasis evolvemen
Background: Abdominal obesity is a risk factor for cardiovascular disease. The aim was to explore the influence of midnight salivary cortisol (MSC), antidepressants and sex on abdominal obesity in type 1 diabetes (T1D). We controlled for physical inactivity, smoking, depression and alexithymia. Methods: Cross sectional study of 190 T1D patients (86 women/104 men, 18-59 years, diabetes duration 1-5
Experimental aerosol generation methods aim to represent natural processes; however, the complexity is not always captured and unforeseen variability may be introduced into the data. The current practices for natural and experimental aerosol generation techniques are reviewed here. Recommendations for best practice are presented, and include characterization of starting material and spray fluid, r
Mer förnybar energi och elektrifiering av transportsektorn är viktiga sätt att minska vår klimatpåverkan. Det ökade intresset för elbilar har också väckt en diskussion om de geopolitiska konsekvenserna av övergången från bensin till batterier. Vilka blir de nya vinnarna och förlorarna i elektrifieringens spår? Vilken typ av naturresurser används i dessa tekniker? Finns det tillräckligt av dessa re
The aim of this work is the development of a thermodynamically consistent fully coupled finite-strain thermo-viscoplastic material model for metals. The model is based on a split of the free energy into a thermo-elastic, a thermo-plastic and a purely thermal part and covers nonlinear cold-work hardening and thermal softening. Nonlinear temperature dependent effects are accounted for the elastic mo
