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Tooth Beads in Two Hunter-Fisher-Gatherer Societies of Northern Europe

Beads made from animal teeth were an important form ofdecoration among hunter-gatherer societies in Northern Europe.The analyses presented in this paper are based on questionsregarding the design of the beads, the choice of animal teeth,their placement on the costume, and the exchange of beads. Forthese analyses, two sites with partly different conditions have beenselected, one located in northernBeads made from animal teeth were an important form of decoration among hunter-gatherer societies in Northern Europe. The analyses presented in this paper are based on questions regarding the design of the beads, the choice of animal teeth, their placement on the costume, and the exchange of beads. For these analyses, two sites with partly different conditions have been selected, one located in no

Is the Effect of Mediterranean Diet on Hip Fracture Mediated through Type 2 Diabetes and Body Mass Index?

BackgroundWe examined whether the inverse association between adherence to a Mediterranean diet and hip fracture risk is mediated by incident type 2 diabetes mellitus (T2DM) and body mass index (BMI).MethodsWe included 50 755 men and women from the Cohort of Swedish Men and the Swedish Mammography Cohort who answered lifestyle and medical questionnaires in 1997 and 2008 (used for calculation of th

Type 2 Diabetes in Relation to Hip Bone Density, Area, and Bone Turnover in Swedish Men and Women: A Cross-Sectional Study

Men and women with type 2 diabetes mellitus (T2DM) have higher risk of hip fracture, but the mechanisms are not fully understood. We aimed to investigate how T2DM, glucose, and insulin were associated with femoral bone mineral density (BMD), bone mineral area (BMA), and bone turnover markers. We used two cross-sectional cohorts: the Uppsala Longitudinal Study of Adult Men (ULSAM, n = 452, mean age

The Free Hormone Hypothesis: Is Free Serum25-Hydroxyvitamin D a Better Marker for Bone Mineral Density in Older Women?

It is presently unclear whether free serum 25 hydroxyvitamin D (S 25(OH)D) better reflects bone health than total S 25(OH)D. We have previously shown that summer total S 25(OH)D values are more useful to predict bone mineral density (BMD) than winter values. Our objective was therefore to compare the relative importance of free and total S 25(OH)D for BMD by season. BMD was measured by dual energy

The seasonal importance of serum 25-hydroxyvitamin D for bone mineral density in older women.

BackgroundThe impact of season when determining a serum 25-hydroxyvitamin D (S-25OHD) cut-off level for optimal bone health is unknown.ObjectiveTo investigate the relative importance of S-25OHD for bone mineral density (BMD) by season.MethodsA subcohort of 5002 Swedish women (mean age 68 years), randomly selected from a large population-based longitudinal cohort study with repeat dietary and lifes

Approaches to mediation analysis in causal inference

This article provides an overview of the role mediation analyses play in causal inferencemethodology and in the estimation of the effect an exposure may have on an outcome throughdirect and indirect pathways. We discuss traditional approaches to mediation and where thesemay lead to bias, before discussing more advanced methods that can be used to overcome thesebiases in situations with single and

Dual design for additive manufacturing in engineering design: a systematic literature review

PurposeDual design for additive manufacturing (DfAM) takes into account both the opportunities and constraints of AM simultaneously, which research shows is more effective than considering them separately. Unlike existing reviews, this paper aims to map DfAM research within the engineering design process, focusing solely on studies adopting dual DfAM. Additionally, it aims to suggest future resear

No Biased Attention to Threat, Incompleteness, and Disgust in Youth with OCD and Anxiety Disorders

Obsessive-compulsive disorder (OCD) and anxiety disorders are early-onset mental disorders characterized by selective attention and strong emotional reactions. Attentional bias has been proposed to play a role in the development, onset, and maintenance of the disorders, but few studies have included youth with mental disorders, and no study has included more than one clinical group, making it uncl

Development and Psychometric Properties of the Pain and Sensitivity Reactivity Scale in a Diverse Sample of Autistic People

Background: Recent studies indicate the need to examine how the gut microbiota–brain axis is implicated in pain, sensory reactivity and gastro-intestinal symptoms in autism spectrum disorder (ASD), but no scale exists that assesses all these constructs simultaneously. Methods: We created a pool of 100 items based on the real-world experience of autistic people, and a multidisciplinary team and sta