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Sun-like stars unlike the Sun : Clues for chemical anomaliesof cool stars

We present a summary of the splinter session “Sun-like stars unlike the Sun” that was held on June 9, 2016, as part of the Cool Stars 19 conference (Uppsala, Sweden), in which the main limitations (in the theory and observations) in the derivation of very precise stellar parameters and chemical abundances of Sun-like stars were discussed. The most important and most debated processes that can prod

Blasts from the Past: War and Fracture in the International System

This article is a brief inquiry into the changing meaning of war in Western political thought, with special reference to its role in fracturing the contemporary international system. I argue that contemporary debates about the changing nature of war have failed to note what I take to be the most important change in our understanding of war in recent decades—the return of the long-suppressed view t

Scalable Design of Heterogeneous Networks

A systematic approach to the analysis and design of a class of large dynamical systems is presented. The approach allows decentralized control laws to be designed independently using only local subsystem models. Design can be conducted using standard techniques, including loopshaping based on Nyquist and Popov plots, H methods, and μ-synthesis procedures. The approach is applied to a range of netw

Adaptation Strategy to Mitigate the Impact of Climate Change on Water Resources in Arid and Semi-Arid Regions : a Case Study

Climate change and drought phenomena impacts have become a growing concern for water resources engineers and policy makers, mainly in arid and semi-arid areas. This study aims to contribute to the development of a decision support tool to prepare water resources managers and planners for climate change adaptation. The Hydrologiska Byråns Vattenbalansavdelning (The Water Balance Department of the H

Sweden, Inc and the campaign to sell JAS-Gripen to the Swiss electorate

In January 2014, it emerged that manufacturer Saab had provided financial backing to the “yes” campaign for a referendum on whether Switzerland should purchase 22 JAS-Gripen aircraft. Although the funds were immediately returned, a second story broke in February revealing the detailed involvement of the Swedish Embassy in the broader coordination of a public diplomacy campaign to support the “yes”

Examining possible neutron-halo nuclei heavier than Mg 37

The even-Z odd-N neutron-halo nuclei, which are the lightest neutron-halo nuclei heavier than Mg37, are explored by studying the shell structure unique in weakly bound neutrons for spherical or deformed shapes. It is pointed out that due to the narrowed N=50 spherical energy gap and a few resulting close-lying neutron one-particle levels, 1g9/2, 3s1/2, and 2d5/2, for spherical shape, nuclei with s

Emerging affinity-based proteomic technologies for large-scale plasma profiling in cardiovascular disease

Plasma biomarkers that reflect molecular states of the cardiovascular system are central for clinical decision making. Routinely used plasma biomarkers include troponins, natriuretic peptides, and lipoprotein particles, yet interrogate only a modest subset of pathways relevant to cardiovascular disease. Systematic profiling of a larger portion of circulating plasma proteins (the plasma proteome) w

Dynamic Modeling of a Parabolic Trough Solar Thermal Power Plant with Thermal Storage Using Modelica

Concentrating solar power (CSP) technology with thermal energy storage is a renewable and emerging technology. In this work, dynamic models for analyzing and evaluating energy storage concepts and its interaction with the solar field and the power block have been developed. A physical model of a 50 MW CSP plant has been implemented in the modeling language Modelica. The models are developed in a m

Factors driving the use of dermoscopy in Europe : a pan-European survey

BACKGROUND: When used correctly, dermoscopy is an essential tool for helping clinicians in the diagnosis of skin diseases and the early detection of skin cancers. Despite its proven benefits, there is a lack of data about how European dermatologists use dermoscopy in everyday practice.OBJECTIVES: To identify the motivations, obstacles and modifiable factors influencing the use of dermoscopy in dai

The impact of dermoscopy on melanoma detection in the practice of dermatologists in Europe : results of a pan-European survey

BACKGROUND: Dermoscopy is a widely used technique that can increase the sensitivity and specificity of melanoma detection. Information is lacking on the impact of dermoscopy use on the detection of melanoma in the real-life practice of European dermatologists.OBJECTIVE: To identify factors that influence the benefit of using dermoscopy for increasing melanoma detection and lowering the number of u

Impacts of land use on climate and ecosystem productivity over the Amazon and the South American continent

The Amazon basin is characterized by a strong interplay between the atmosphere and vegetation. Anthropogenic land use and land cover change (LULCC) affects vegetation and the exchange of energy and water with the atmosphere. Here we have assessed potential LULCC impacts on climate and natural vegetation dynamics over South America with a regional Earth system model that also accounts for vegetatio

Subthalamic nucleus lesioning inhibits expression and phosphorylation of c-Jun in nigral neurons in the rat's 6-OHDA model of Parkinson's disease

Parkinson's Disease (PD) is characterized by a loss of nigral dopamine (DA) neurons, followed by a striatal DA deficit. Inhibition of the subthalamic nucleus (STN) reverses L-DOPA sensitive motor symptoms and improves efficacy of pharmacotherapy in PD-patients. The underlying mechanism of these effects, however, remains largely unknown. Previously, we could show in the rat's 6-hydroxyDA (6-OHDA) m

36 h fasting of young men influences adipose tissue DNA methylation of LEP and ADIPOQ in a birth weight-dependent manner

Background: Subjects born with low birth weight (LBW) display a more energy-conserving response to fasting compared with normal birth weight (NBW) subjects. However, the molecular mechanisms explaining these metabolic differences remain unknown. Environmental influences may dynamically affect epigenetic marks, also in postnatal life. Here, we aimed to study the effects of short-term fasting on lep

High-frequency stimulation of the subthalamic nucleus enhances striatal dopamine release and metabolism in rats

High-frequency stimulation of the subthalamic nucleus is believed to exert its main effects via the basal ganglia output structures. Previously, we have shown a concomitant increase in striatal dopamine (DA) metabolites in normal and 6-hydroxydopamine-lesioned rats. The present study was designed to determine whether this increase in striatal DA metabolites reflects enhanced intraneuronal DA turno

Soil microbial responses to mild winters and seasonal change

Varje år släpps ungefär 10 gånger mer koldioxid ut av mikroorganismer som lever i jorden vi går på, jämfört med utsläppen som kommer från fossila bränslen. Som tur är tar växter upp ungefär lika mycket koldioxid från atmosfären som mikroorganismerna släpper ut, så de balanserar varandra. En viktig fråga är vad som händer med balans mellan växter och mikroorganismer om klimatet blir varmare. Om växThe aim with this thesis work was to study microorganisms response to milder winters, different seasons, and altered temperature. Winter warming treatments were established in a semi-natural temperate grassland, simulating mild winters for two years. We found that arbuscular mycorrhizal (AM) fungi received more carbon (C) from the plants after experiencing milder winters. The amount of plant-deriv

Respiratory chain complex III deficiency due to mutated BCS1L : A novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model

Background: Mitochondrial diseases due to defective respiratory chain complex III (CIII) are relatively uncommon. The assembly of the eleven-subunit CIII is completed by the insertion of the Rieske iron-sulfur protein, a process for which BCS1L protein is indispensable. Mutations in the BCS1L gene constitute the most common diagnosed cause of CIII deficiency, and the phenotypic spectrum arising fr

Deep brain stimulation of subthalamic neurons increases striatal dopamine metabolism and induces contralateral circling in freely moving 6-hydroxydopamine-lesioned rats

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) alleviates Parkinson's disease (PD) symptoms. Although widely used, the mechanisms of action are still unknown. In an attempt to elucidate those mechanisms, we have previously demonstrated that STN-DBS increases striatal extracellular dopamine (DA) metabolites in anaesthetized rats. PD being a movement disorder, it remains to be determi