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Lipase-immobilized chitosan-crosslinked magnetic nanoparticle as a biocatalyst for ring opening esterification of itaconic anhydride

Nano-magnetic biocatalyst particles, lipase-immobilized chitosan-crosslinked magnetic nanoparticles (LCMNs) were prepared by a new approach integrated from magnetic nanoparticle preparation, in situ thin layer coating and crosslinking of chitosan, and enzyme immobilization method. Thin layer coating of magnetic (Fe3O4) by crosslinked chitosan nanoparticles were prepared by reacting FeCl3.6H2O and

The origins of Roman bricks : a similarity network approach

This paper addresses the question of the origin of Roman fired bricks from the perspective of diffusion of innovations. It is seen as a part of a larger process, related to cultural evolution and the transferal of behavioural habits through social interaction. Fired bricks are particularly well suited to shed light on this topic, since the diffusion of bricks was both irregular and extended over a

Skim milk powder with high content of Maillard reaction products affect weight gain, organ development and intestinal inflammation in early life in rats

Background: The intestinal tract is important for development of immune tolerance and disturbances are suggested to trigger autoimmune disorders. The aim of this study was to explore the effect of Maillard products in skim milk powder obtained after long storage, compared to fresh skim milk powder. Methods: Young rats were weaned onto a diet based on skim milk powder with high concentration of Mai

A Bayesian method to localize lost gamma sources

A feasibility study of a Bayesian based algorithm for orphan source localization by means of mobile gamma spectrometry is presented. The method was tested on three types of gamma sources (137Cs, 133Ba and 131I) using a HPGe detector mounted on a vehicle. Estimates on source activity and source locations were within 51% and 29% of actual values, respectively. Further studies are required to validat

Soluble CD163 was linked to galectin-3, diabetic retinopathy and antidepressants in type 1 diabetes

OBJECTIVE: Depression has been associated with diabetic retinopathy and increased plasma levels of galectin-3, a lectin expressed in activated macrophages. Increased levels of sCD163, the soluble form of a macrophage expressed scavenger receptor involved in several inflammatory processes, have been demonstrated in the vitreous of the eye in type 1 diabetes (T1D) patients with severe diabetic retin

Business models for sustainable consumption in the circular economy : An expert study

Combining sustainable consumption with the circular economy concept could help tackle challenges, such as resource scarcity and climate change by reducing resource throughput and increasing cycling of products and materials within the economic system, thereby reducing emissions and virgin material use. To achieve sustainable consumption in a circular economy production and consumption practices ne

Insulin induces Thr484 phosphorylation and stabilization of SIK2 in adipocytes

AIMS/HYPOTHESIS: Salt-inducible kinase 2 (SIK2) is downregulated in adipose tissue from obese or insulin-resistant individuals and inhibition of SIK isoforms results in reduced glucose uptake and insulin signalling in adipocytes. However, the regulation of SIK2 itself in response to insulin in adipocytes has not been studied in detail. The aim of our work was to investigate effects of insulin on v

The hand gesture and symbols of Sabazios

The material evidence left from the cult of Sabazios is meagre, apart from sculpted bronze hands dating to the Roman Empire. The hand is held in a certain pose, the so-called benedictio Latina gesture, and the hand was often covered with depictions of various objects and symbols. The bronze hands were probably attached to staffs and carried around in processions. This practice most likely spread v

Are values related to culture, identity, community cohesion and sense of place the values most vulnerable to climate change?

Values related to culture, identity, community cohesion and sense of place have sometimes been downplayed in the climate change discourse. However, they have been suggested to be not only important to citizens but the values most vulnerable to climate change. Here we test four empirical consequences of the suggestion: (i) at least 50% of the locations citizens' consider to be the most important lo

The Effect of Radioiodine Treatment on TRAb, Anti-TPO, and Anti-TG in Graves' Disease

Background: In Graves' disease (GD), immunocompetent cells infiltrate thyroid tissue with release of TSH-receptor antibodies (TRAb), and radioiodine treatment is known to elicit an immune response with an increase in TRAb. Objectives: The aim was to study if all patients treated with radioiodine respond with a release of TRAb, anti-thyroperoxidase (anti-TPO), and anti-thyroglobulin (anti-TG). Meth

Selecting Ministers in Times of Crisis : A Historical Analysis of the Role of Intra-Party Politics and Union Background in Swedish Cabinet Appointments 1917–2014

In this article, we connect intra-party politics to macro events by asking what types of ministers are selected in times of fiscal crisis. Drawing on the previous literature we present two alternative hypotheses about the role of the union background in cabinet selection: (1) ministers with union background are less likely to be appointed during crises, since they are likely to oppose necessary sp

Fractional flow reserve-guided percutaneous coronary intervention vs. medical therapy for patients with stable coronary lesions : meta-analysis of individual patient data

Aims: To assess the effect of fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) with contemporary drug-eluting stents on the composite of cardiac death or myocardial infarction (MI) vs. medical therapy in patients with stable coronary lesions. Methods and results: We performed a systematic review and meta-analysis of individual patient data (IPD) of the three available

Heat wave–related mortality in Sweden : A case-crossover study investigating effect modification by neighbourhood deprivation

Aims: The present study aimed to investigate if set thresholds in the Swedish heat-wave warning system are valid for all parts of Sweden and if the heat-wave warning system captures a potential increase in all-cause mortality and coronary heart disease (CHD) mortality. An additional aim was to investigate whether neighbourhood deprivation modifies the relationship between heat waves and mortality.

PATJ Low Frequency Variants Are Associated With Worse Ischemic Stroke Functional Outcome

RATIONALE: Ischemic stroke is among the leading causes of adult disability. Part of the variability in functional outcome after stroke has been attributed to genetic factors but no locus has been consistently associated with stroke outcome. OBJECTIVE: Our aim was to identify genetic loci influencing the recovery process using accurate phenotyping to produce the largest GWAS (genome-wide associatio