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Importance: Quality of life is not a standard primary outcome in ablation trials, even though symptoms drive the indication.Objective: To assess quality of life with catheter ablation vs antiarrhythmic medication at 12 months in patients with atrial fibrillation.Design, Setting, and Participants: Randomized clinical trial at 4 university hospitals in Sweden and 1 in Finland of 155 patients aged 30
AIMS: To assess the efficacy of the 2nd generation Cryoballoon for pulmonary vein isolation (PVI) in patients with persistent atrial fibrillation (PersAF), and to compare it to patients with paroxysmal atrial fibrillation (PAF).METHODS: The outcome (arrhythmia recurrence at 12 months) was prospectively assessed in patients with PersAF(n = 77) and compared to that in patients with PAF(n = 62), who
Aims: A single cryoballoon (CB) application per vein for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF) could save time and was therefore compared to the standard approach of two consecutive CB applications for acute and long-term efficacy and safety.Methods and results: Patients with symptomatic AF were randomized to a single CB application per vein guided by an Achieve®
BACKGROUND: Patients with a high ventricular rate during atrial fibrillation (AF) are at increased risk of receiving inappropriate implantable cardioverter defibrillator shocks. The objective was to demonstrate the feasibility of high frequency atrioventricular-nodal stimulation (AVNS) to reduce the ventricular rate during AF to prevent inappropriate implantable cardioverter defibrillator shocks.M
Atrial fibrillation (AF) is a common disease with a high prevalence in the adult population. Treatment of AF encompasses antiarrhythmic drugs and catheter ablation to reduce symptoms. The aim of this thesis was to study how to best alleviate symptoms of AF in a safe and efficient way comparing pharmacological treatment and the two dominating catheter ablation techniques, cryoballoon (CRYO) ablatio
Review of Katherine Verdery's autobiographical work in which she describes her fieldwork in Romania from 1973 to 1988 using the 2781 pages of her Romanian secret police file, in which he is code named "Vera". This is the story of how "Kathy" meets "Vera".
We assessed the contribution of blood pressure (BP), inflammation, and endothelial activation to the development of structural vascular and cardiac changes in hypertension. Furthermore, the effects of antihypertensive therapy were studied. We studied 114 patients with hypertension and left ventricular hypertrophy and 38 matched hypertensive subjects without cardiac hypertrophy and 38 normotensive
BACKGROUND: Permanent pacemaker implantation (PPM) early after cardiac transplantation has been shown not to predict a worse outcome. However, the requirement for pacing late after transplantation and its prognostic implications are not fully known. We describe the clinical indications, risk factors and long-term outcome in patients who required pacing early and late after transplantation.METHODS:
With transparency being either a state of clarity or the exposure emptiness, this paper focuses on the practices of transparency, termed ‘transparenting’. Focus on transparenting practices can provide a better tool for understanding the ‘rise of transparency’, and its moral, practical and political aspects. Three types of transparenting are defined: the voluntary transparenting conducted by organ
Males of both juveniles and adults had significantly longer wings than females, the difference between the sexes being c5.5%. Using wing length as the only criterion, between 97.4% and 88.6% of juveniles and between 98.0% and 93.4% of adults can be unambiguously sexed during autumn/winter. Individuals measured during their second or later autumn/winter had significantly longer wings than those mea
At least nine hypotheses have been advanced to account for why many passerine species hatch their clutches asynchronously: 1) The brood reduction hypothesis; 2) The peak load reduction hypothesis; 3) The sibling rivalry reduction hypothesis; 4) The hurry-up hypothesis; 5) The egg viability hypothesis; 6) The sexual conflict hypothesis; 7) The equal investment hypothesis; 8) The nest failure hypoth
This article recapitulates the effect of my early fieldwork in socialist Romania, in which people's coping with bureaucracy through informal mechanisms of improvization, corruption, rumor creation, etc. come to mark by subsequent research interest, like a tatoo, and like the electronic ankle bracelet on the home prisoner, tend to pull me back into the same kind of theme, for better or for worse. C
This paper argues that the concept of whistleblowing could best be understood as part of a larger regime of disclosure that includes personal revelations, truth-telling, leaking, informing, snitching and whistleblowing. Disclosure regimes are about knowledge that escapes. This paper discusses the conditions for this escaped knowledge and some of the consequences for organizations and communities.
Objective: To compare iron stores in infants born after elective caesarean section (CS) and a 30 s delay of umbilical cord clamping with those born vaginally after early (≤10 s) or delayed (≥180 s) cord clamping. Design: Prospective observational study with historical control. Setting: Swedish county hospital. Population: 64 infants born after elective CS were compared with a historical control of
Objective. To investigate the effect of delayed cord clamping (DCC) compared with early cord clamping (ECC) on maternal postpartum hemorrhage (PPH) and umbilical cord blood gas sampling. Design. Secondary analysis of a parallel-group, single-center, randomized controlled trial. Setting. Swedish county hospital. Population. 382 term deliveries after a low-risk pregnancy. Methods. Deliveries were ra
The pandemic of chronic non-communicable diseases (NCDs) poses substantial challenges to the health financing sustainability in high-income and low/middle income countries (LMICs). The aim of this review is to identify the bottle neck inefficiencies in NCDs attributable spending and propose sustainable health financing solutions. The World Health Organization (WHO) introduced the "best buy" concep
The heaviest currently known nuclei, which have up to 118 protons, have been produced in 48Ca induced reactions with actinide targets. Among them, the element tennessine (Ts), which has 117 protons, has been synthesized by fusing 48Ca with the radioactive target 249Bk, which has a half-life of 327 d. The experiment was performed at the gas-filled recoil separator TASCA. Two long and two short α de
