Background: The goals of palliative care are to relieve suffering and promote quality of life. Palliative care for older persons has been less prioritised than palliative care for younger people with cancer, which may lead to unnecessary suffering and decreased quality of life at the final stage of life.Aim: To evaluate whether a palliative care intervention had any influence on the perceived qual

Governments in countries across the world increasingly adopt the “green growth” discourse to underline their ambition for the greening of their economies. The central tenet of this narrative is the economic opportunities rather than challenges arising from the pursuit of environmental sustainability. Our paper synthesises insights from 113 recent scientific articles, dealing with both environmenta

Heavy rainfall and flooding in late March and early April 2019 affected millions of people in Iran, caused deaths, displacement and catastrophic damage to the infrastructure. This is happening while the country has long suffered from frequent droughts and adaptive management practices are not in place to deal with such fluctuations.

What Andrei Novac intends to restore is the poetry that could have written more to Romania if it had not dismantled by the communism which lasted 45 years. The technique resides in allegories, allusions, parodies, cryptic experiments (in the best cases, because it is pointless to mention the disastrous poetic manifestations). As the basic notion of the volume is responsible and sensitive freedom,

BACKGROUND: A better definition of biomarkers and biological processes related to local recurrence and disease progression is highly warranted for ductal breast carcinoma in situ (DCIS). Stromal-epithelial interactions are likely of major importance for the biological, clinical, and pathological distinctions between high- and low-risk DCIS cases.METHODS: Stromal platelet derived growth factor rece

Perivascular cells (PC) were recently implied as regulators of metastasis and immune cell activity. Perivascular heterogeneity in clinical samples, and associations with other tumor features and outcome, remain largely unknown.Here we report a novel method for digital quantitative analyses of vessel characteristics and PC, which was applied to two collections of human metastatic colorectal cancer

PURPOSE: Hypoxia is one of the most important factors influencing clinical outcome after radiotherapy. Improved knowledge of factors affecting the levels and distribution of oxygen within a tumor is needed. The authors constructed a theoretical 3D model based on histological images to analyze the influence of vessel density and hemoglobin (Hb) concentration on the response to irradiation.METHODS:

An 80-year old male presented with an infected knee replacement following repeated joint aspirations. They were carried out due to recurrent hemarthrosis resulting from an initially missed quadriceps tendon injury. The infection was eradicated first after arthrodesis. This case highlights that prosthetic joints are sensitive to infection, which once established can be difficult to eradicate. Caref

In The 21st-Century Voice: Contemporary and Traditional Extra-Normal Voice, Michael Edward Edgerton considers contemporary vocal techniques within an acoustic and anatomical framework. Throughout, he proposes new directions for vocal exploration. Much more than a historical treatise on 20th-century masterworks or vocal science, The 21st-Century Voice explores experimental methods of sound producti

Objective. Obsessive-compulsive disorder (OCD) is a heterogeneous condition with well-established symptom dimensions across the lifespan. The objective of the present study was to use network analysis to investigate the internal structure and central features of these dimensions in unselected schoolchildren and in youth with OCD.Method. We estimated the network structure of OCD symptom dimensions

This monograph presents a working description of a special class of acoustical outputs, termed extra-complex sonorities that are the result of desynchronizing robust parameters involved in the production of sound within scaled and multidimensional networks by instruments and voices. The purpose of such a description is to provide a framework for understanding the mechanical and perceptual aspects

This article will present a single case study of the acoustic attributes of sound production techniques that are involved in the expansion of performance practice with the violin. In this study, four elements were chosen from the multidimensional network involved in playing a normal tone, and then each was intentionally decoupled from ordinario. These elements (bow speed, bow placement, bow angle,

I alla vardagliga situationer och relationer gör sig inblandade personers känslor påminda på olika sätt. Det kan få en stor inverkan på utfallet av mänskliga möten i skilda sammanhang. I den ”juridiska världen” har detta länge varit en icke-fråga. Juridiken är till sin natur rationell och objektiv och det gäller juristen också. Så har det sagts. Men detta är av allt att döma en grov förenkling. I

The influence of wind is only occasionally accounted for in fire safety engineering, still the effect of wind on, for example, the performance of a smoke management system can be large. A simple analytical method to account for the effect of wind on mass flow through horizontal openings for natural ventilation is compared to results from CFD simulations in this paper. It is seen that the correspon

Nine participants, representing eight different Swedish fire consultancy firms participated in a Round Robin study where two different fire scenarios were simulated with the Fire Dynamics Simulator. The participants were given clear instructions on the building layout and heat release rate for the two scenarios. Still, the results demonstrate a significant variation in time to sprinkler system act