Objective To develop a disease activity index for patients with primary Sjogren's syndrome (SS): the European League Against Rheumatism (EULAR) Sjogren's syndrome disease activity index (ESSDAI). Methods Thirty-nine SS experts participated in an international collaboration, promoted by EULAR, to develop the ESSDAI. Experts identified 12 organ-specific 'domains' contributing to disease activity. Fo

The enantiomeric lactams (-)-8, (+)-8, (+)-9, and (-)-9 were formed by the reaction of the dimeric phthalide rac-tokinolide B (rac-3) with (R)-(+)-alpha-methylbenzylamine and (S)-(-)-alpha-methylbenzylamine. The absolute configurations of compounds 8 and 9 were assigned by experimental and theoretically calculated electronic circular dichroism methods for (+)-8 and (-)-9. Compounds 3, 5, (-)-8, (+

The three works analyzed here were published at the culmination of Swedish romanticism. The strange mixture of the high and the low, the sacred and the profane that is typical for them has been an interesting challenge for literary scholars. For instance, in older research one sometimes spoke of poor handwork, or bad taste of the writers or it was explained that these works were a stage between th

A measurement technique capable of recording three-dimensional laser induced images with a spatial resolution of 610x512x20 voxels over a volume of 29x24x15 mm(3) and at a frame rate of 1 kHz is presented. A novel approach for sweeping the illuminating laser sheet across the investigated volume is introduced as a key feature. The technique is applied to imaging nebulized water droplets with a nitr

The aim of this study was to gain insights into the tempo and mode of the evolutionary processes that sustain genetic diversity in coxsackievirus B5 (CVB5) and into the interplay with virus transmission. We estimated phylodynamic patterns with a large sample of virus strains collected in Europe by Bayesian statistical methods, reconstructed the ancestral states of genealogical nodes, and tested fo

The overall aim of the thesis was to investigate and explore job satisfaction, strain and stress of conscience (SC) among nurse assistants (NAs) working in residential care for older people. The thesis had a descriptive, cross-sectional and correlational design and consisted of one paper where qualitative methodology was used and three where quantitative methodology was used. The qualitative study

Emergency department (ED) crowding is an increasing problem in many countries. The purpose of this study was to develop a quantitative model that estimates the degree of crowding based on workload in Swedish EDs.

ObjectiveTo study the predictive value of biphasic ST-events for interventions for suspected fetal distress and adverse neonatal outcome, when using ST-analysis of the fetal electrocardiogram (FECG) for intrapartum fetal monitoring. DesignProspective cohort study. SettingThree academic hospitals in Sweden. PopulationWomen in labor with a high-risk singleton fetus in cephalic position beyond 36week

A characteristic feature of non-muscle-invasive bladder cancer (NMIBC) is the high risk of recurrent disease after primary treatment. Although only a minority of cases eventually progress to a life-threatening muscle-invasive tumour, it is necessary to conduct long-term follow-up with repeated cystoscopies. In addition to the negative mental and physical impact that this has on the patient, the ex

Background and purpose We have previously shown in a randomized study that in the first year after treatment, open reduction and internal fixation resulted in better grip strength and forearm rotation than closed reduction and bridging external fixation. In the present study, we investigated whether this difference persists over time. Patients and methods The 50 patients included in the original s

The integration of scheduling and control in the process industry is a topic that has been frequently discussed during the recent years, but many challenges remain in order to obtain integrated solutions that may be implemented at large-scale industrial sites. This paper introduces a general framework for production scheduling (PS) and detailed production scheduling (DPS) using a two-level hierarc

Abstract in UndeterminedIn this study, sparse modeling is introduced for the estimation of propagation patterns in intracardiac atrial fibrillation (AF) signals. The estimation is based on the partial directed coherence function, derived from fitting a multivariate autoregressive model to the observed signal using least-squares (LS) estimation. The propagation pattern analysis incorporates prior i

The objective with this work is to compare the adhesive behavior for latex polymers of different glass transition temperatures (T-g) at different length scales and with different contact times. This is accomplished by two techniques: AFM colloidal probe force measurements and JKR-measurements. The aim is to compare the results from these two techniques and relate them to the interaction of the lat

The technique of longitudinal ("xyz") polarization analysis has been used successfully for many years to study disordered magnetic materials in thermal and cold neutron diffraction experiments. The technique allows the simultaneous and unambiguous separation of the nuclear, magnetic, and nuclear spin-incoherent contributions to the scattering. The technical advances seen in recent years, such as t