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Plastic extension of Breviario de espejismos by Elena Mendoza. Glued paper, two speakers, amplifier, video, tablet, LED light, photographic montage, four metal supports, fishing line, metal strings, two wooden boxes, two mixed metal-wooden supports.

Mixed halide perovskites for spectrally stable and high-efficiency blue light-emitting diodes

Bright and efficient blue emission is key to further development of metal halide perovskite light-emitting diodes. Although modifying bromide/chloride composition is straightforward to achieve blue emission, practical implementation of this strategy has been challenging due to poor colour stability and severe photoluminescence quenching. Both detrimental effects become increasingly prominent in pe

Intranasal administration of α-synuclein preformed fibrils triggers microglial iron deposition in the substantia nigra of Macaca fascicularis

Iron deposition is present in main lesion areas in the brains of patients with Parkinson’s disease (PD) and an abnormal iron content may be associated with dopaminergic neuronal cytotoxicity and degeneration in the substantia nigra of the midbrain. However, the cause of iron deposition and its role in the pathological process of PD are unclear. In the present study, we investigated the effects of

The patterns of family genetic risk scores for eleven major psychiatric and substance use disorders in a Swedish national sample

To clarify the structure of genetic risks for 11 major psychiatric disorders, we calculated, from morbidity risks for disorders in 1st–5th degree relatives controlling for cohabitation effects, in the Swedish population born between 1932 and 1995 (n = 5,830,014), the family genetic risk scores (FGRS) for major depression (MD), anxiety disorders (AD), obsessive-compulsive disorder (OCD), bipolar di

Predictors of outcome in children with disorders of mitochondrial metabolism in the pediatric intensive care unit

Background: The aim of this study was to identify factors predicting outcome in patients with mitochondrial disease admitted to pediatric intensive care units (PICU). Methods: Retrospective study of 2434 patients (age <21 years) admitted to a PICU from 1 January 2006 through 31 March 2016 and captured in the Virtual Pediatric Systems database with ICD9 diagnosis 277.87, disorders of mitochondrial

Expression patterns and prognostic potential of circular RNAs in mantle cell lymphoma : a study of younger patients from the MCL2 and MCL3 clinical trials

Mantle cell lymphoma (MCL) is characterized by marked differences in outcome, emphasizing the need for strong prognostic biomarkers. Here, we explore expression patterns and prognostic relevance of circular RNAs (circRNAs), a group of endogenous non-coding RNA molecules, in MCL. We profiled the circRNA expression landscape using RNA-sequencing and explored the prognostic potential of 40 abundant c

Value of flow cytometry for MRD-based relapse prediction in B-cell precursor ALL in a multicenter setting

PCR of TCR/Ig gene rearrangements is considered the method of choice for minimal residual disease (MRD) quantification in BCP-ALL, but flow cytometry analysis of leukemia-associated immunophenotypes (FCM-MRD) is faster and biologically more informative. FCM-MRD performed in 18 laboratories across seven countries was used for risk stratification of 1487 patients with BCP-ALL enrolled in the NOPHO A

The role of cross-linking in the scratch resistance of organic coatings: an investigation using atomic force microscopy

Understanding how the composition of organic coatings influences their ability to resist surface damage during use remains a challenge. A relevant potential influence is that of cross-linking density. This parameter is frequently used for tailoring the mechanical properties of organic coatings and it manifests itself in terms of scratch resistance. However, the mechanisms that influence scratch re

Atomically sharp, crystal phase defined GaAs quantum dots

Crystal phase defined heterostructures, or polytype heterostructures, are atomically sharp with no intermixing, which makes them ideal contenders for a wide number of applications. Although polytype quantum dots have shown promising results as single photon sources, a high degree of control on the dimensions and number of polytype quantum dots is necessary before any application can be developed.I

LOVE a Pairing

The problem of securely outsourcing the computation of a bilinear pairing has been widely investigated in the literature. Designing an efficient protocol with the desired functionality has, however, been an open challenge for a long time. Recently, Di Crescenzo et al. (CARDIS’20) proposed the first suite of protocols for securely and efficiently delegating pairings with online inputs under the pre

Humidity-Induced Phase Transitions of Surfactants Embedded in Latex Coatings Can Drastically Alter Their Water Barrier and Mechanical Properties

Latex coatings are environmentally friendly i.e., they are formed from aqueous polymer dispersions, are cheap to produce and provide exceptional mechanical properties. Therefore, they are ubiquitous and can be found in a wide range of different applications such as paints and varnishes, pressure-sensitive adhesives, textiles, construction materials, paper coatings and inks. However, they also have

Whose Freedom is it Anyway? The Fundamental Rights of Companies in EU Law

Companies enjoy increasingly extensive protection of their fundamental right to conduct business under EU law. This article will examine whether this protection is justified by reference to the foundational value of human freedom. In other words, does the way in which EU law protects the fundamental rights of companies to conduct business promote the freedom of individuals human beings within the

Comparison of the prevalence of glutamic acid decarboxylase (GAD65) and gliadin antibodies (AGA) in a randomly selected adult estonian population

We aimed to test the hypothesis that gluten might be associated with the development of islet cell autoimmunity. A random sample of 200 persons (87 males, mean age 42.4 years) from Estonia including one patient with type I diabetes mellitus was studied. IgG-type glutamic acid decarboxylase (GAD65) antibodies were determined using radioligand-binding assay and IgG/IgA-type gliadin antibodies (AGA)

Using Human Genetics to Understand Mechanisms in Ischemic Stroke Outcome : From Early Brain Injury to Long-Term Recovery

There is a critical need to elucidate molecular mechanisms underlying brain injury, repair, and recovery following ischemic stroke-a global health problem with major social and economic impact. Despite 5 decades of intensive research, there are no widely accepted neuroprotective drugs that mitigate ischemic brain injury, or neuroreparative drugs, or personalized approaches that guide therapies to